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Alpha-2 blockers

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Alpha blockers (13)
Antihypertensive agents (13)
Drugs acting on the cardiovascular system (13)
Drugs acting on the genito-urinary system (13)
Drugs for benign prostatic hyperplasia (13)
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Cyclic compounds (10)
Drugs acting on the nervous system (9)
Psychoactive drugs (9)
Six-membered rings (7)
Pharmaceuticals (6)
Psychopharmacology (6)
Antihistamines (5)
H1 receptor antagonists (5)
Alpha-1 blockers (4)
Antidepressants (4)
Aromatic compounds (4)
Dopamine antagonists (4)
Piperazines (4)
Antipsychotics (3)
D2 antagonists (3)
Five-membered rings (3)
Fluoroarenes (3)
Imidazolines (3)
Nervous system drug (3)
Noradrenergic and specific serotonergic antidepressants (3)
Organic compound (3)
Piperidines (3)
Tetracyclic antidepressants (3)
Antiparkinsonian agents (2)
Atypical antipsychotics (2)
D3 antagonists (2)
Dopamine agonists (2)
Psychoanaleptics (2)
Pyrimidines (2)
Antihypertensive agent (1)
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Chloroarenes (1)
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D2-receptor agonists (1)
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Mood stabilizers (1)
Serotonin-norepinephrine-dopamine releasing agents (1)
Stimulants (1)
Typical antipsychotics (1)

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Sigma Aldrich (5)
TCI Chemicals (5)
AK Scientific (4)
Matrix Scientific (3)
Toronto Research Chemicals (2)
Accela (1)
Apollo Scientific (1)
Frontier Scientific (1)
Oakwood Chemical (1)
SynQuest Laboratories (1)

Aripiprazole (129722-12-9)  
Aripiprazole, sold under the brand name Abilify among others, is an atypical antipsychotic. From April 2013 to March 2014, sales of Abilify amounted to almost $6.9 billion.. It is recommended by some doctors and used in the treatment of schizophrenia and bipolar disorder.
mirtazapine (61337-67-5, 85650-52-8)  
Remeron  ·  Rexer  ·  ORG 3770
Mirtazapine, sold under the brand name Remeron among others, is an atypical antidepressant which is used primarily in the treatment of depression. In addition to its antidepressant properties, mirtazapine has anxiolytic, sedative, antiemetic, and appetite stimulant effects and is sometimes used in the treatment of anxiety disorders, insomnia, nausea and vomiting, and to produce weight gain when desirable. It is taken by mouth.
Esmirtazapine (61337-87-9)  
mirtazapine  ·  Remeron  ·  Rexer
Esmirtazapine (ORG-50,081) is a drug which was under development by Organon for the treatment of insomnia and vasomotor symptoms (e.g., hot flashes) associated with menopause. Esmirtazapine is the (S)-(+)-enantiomer of mirtazapine and possesses similar overall pharmacology, including inverse agonist actions at H1 and 5-HT2 receptors and antagonist actions at α2-adrenergic receptors. As of March 2010, Merck terminated internal clinical development program for esmirtazapine, for hot flashes and insomnia, for strategic reasons.
Ketanserin (83846-83-7, 74050-98-9)  
R 41468  ·  R-41468  ·  R-41,468
Ketanserin (INN, USAN, BAN) (brand name Sufrexal; former developmental code name R41468) is a drug used clinically as an antihypertensive agent and in scientific research to study the serotonin system; specifically, the 5-HT2 receptor family. It was discovered at Janssen Pharmaceutica in 1980.
Pipamperone (1893-33-0)  
R 3345  ·  Dipiperon  ·  1'-(3-(4-fluorobenzoyl)propyl)-(1,4'-bipiperidine) -4'-carboxamide
Pipamperone (INN, USAN, BAN), also known as carpiperone and floropipamide or fluoropipamide, and as floropipamide hydrochloride (JAN), is a typical antipsychotic of the butyrophenone family used in the treatment of schizophrenia. It is or has been marketed under brand names including Dipiperon, Dipiperal, Piperonil, Piperonyl, and Propitan. Pipamperone was discovered at Janssen Pharmaceutica in 1961, and entered clinical trials in the United States in 1963.
MELPERONE (3575-80-2)  
Melperone (Bunil (PT), Buronil (AT, BE, CZ, DK, FL†, NL†, NO†, SE), Eunerpan (DE)) is an atypical antipsychotic of the butyrophenone chemical class, making it structurally related to the typical antipsychotic haloperidol. It first entered clinical use in 1960s.
piribedil (3605-01-4)  
ET 495  ·  Trivastal  ·  Piribedil Mesylate
Piribedil (trade names Pronoran, Trivastal Retard, Trastal, Trivastan, Clarium and others) is an antiparkinsonian agent and piperazine derivative which acts as a D2 and D3 receptor agonist. It also has α2-adrenergic antagonist properties.
2-(1-Piperazinyl)pyrimidine (125523-53-7, 20980-22-7)  
MJ-13653  ·  1-(2-pyrimidinyl)piperazine  ·  MJ 13653
1-(2-Pyrimidinyl)piperazine (1-PP, 1-PmP) is a chemical compound and piperazine derivative. It is known to act as an antagonist of the α2-adrenergic receptor (Ki = 7.3–40 nM) and, to a much lesser extent, as a partial agonist of the 5-HT1A receptor (Ki = 414 nM; Emax = 54%). It has negligible affinity for the dopamine D2, D3, and D4 receptors (Ki > 10,000 nM) and does not appear to have significant affinity for the α1-adrenergic receptors.
1-Benzylpiperazine (2759-28-6)  
1-benzylpiperazine hydrochloride  ·  1-benzylpiperazine tartrate  ·  1-benzylpiperazine dihydrochloride
Benzylpiperazine (BZP) is a recreational drug with euphoriant and stimulant properties. The effects produced by BZP are comparable to those produced by amphetamine. Adverse effects have been reported following its use including acute psychosis, renal toxicity and seizures.
Efaroxan (89197-32-0)  
Efaroxan is an α2-adrenergic receptor antagonist and antagonist of the imidazoline receptor.
Brl-44408 (118343-19-4)  
BRL-44408 is a drug used in scientific research which acts as a selective antagonist for the α2A adrenoreceptor. It has been suggested as having potential therapeutic application in the treatment of extrapyramidal side effects produced by some antipsychotic medications.

Related Results:
losartan (114798-26-4)  
Cozaar  ·  Losartan Potassium  ·  DuP 753
Losartan, sold under the trade name Cozaar among others, is a medication mainly used to treat high blood pressure. Other uses include for diabetic kidney disease, heart failure, and left ventricular enlargement. It is taken by mouth.
Candesartan cilexetil (145040-37-5)  
Amias  ·  Atacand  ·  Kenzen
Candesartan (rINN) is an angiotensin II receptor antagonist used mainly for the treatment of hypertension. The prodrug candesartan cilexetil is marketed by AstraZeneca and Takeda Pharmaceuticals, commonly under the trade names Diceran,Blopress, Atacand, Amias, and Ratacand. It is available in generic form.
Enalapril maleate (75847-73-3, 76095-16-4, 76420-75-2)  
Enalapril  ·  MK 421  ·  Renitec
Enalapril, sold under the brand name Vasotec among others, is a medication used to treat high blood pressure, diabetic kidney disease, and heart failure. For heart failure it is generally used with a diuretic such as furosemide. It is given by mouth or injection into a vein.
lisinopril (77726-95-5, 76547-98-3, 83915-83-7)  
Zestril  ·  Prinivil  ·  MK-521
Lisinopril is a drug of the angiotensin-converting enzyme (ACE) inhibitor class used primarily in treatment of high blood pressure, heart failure, and after heart attacks. It is also used for preventing kidney and eye complications in people with diabetes. Its indications, contraindications, and side effects are as those for all ACE inhibitors.
fosinopril (98048-97-6)  
Monopril  ·  Fosinopril Sodium  ·  Tenso Stop
Fosinopril is an angiotensin converting enzyme (ACE) inhibitor used for the treatment of hypertension and some types of chronic heart failure. Fosinopril is the only phosphinate-containing ACE inhibitor marketed, by Bristol-Myers Squibb under the trade name Monopril.
6950-04-5 (51833-69-3, 6950-04-5, 5486-06-6)  
angiotensin II, sarcosyl(1)-isoleucine(5)-  ·  angiotensin II, Sar(1)-Ile(5)-, (7-D-Pro)-isomer  ·  angiotensin II, Sar(1)-Ile(5)-
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