Related to BUTACHLOR, Antiandrogens, Five-membered rings
Cyclic compounds (1)
Hormonal agents (1)
Sex hormones (1)
Buserelin Acetate · Suprefact · HOE 766
Buserelin, sold under the brand name Suprefact among others, is a medication which is used primarily in the treatment of prostate cancer and endometriosis. It is also used for other indications such as the treatment of premenopausal breast cancer, uterine fibroids, and early puberty, in assisted reproduction for female infertility, and as a part of transgender hormone therapy. In addition, buserelin is used in veterinary medicine.
Arimidex · anastrazole · Zeneca brand of anastrozole
Anastrozole, sold under the brand name Arimidex among others, is a medication used in addition to other treatments for breast cancer. Specifically it is used for hormone receptor-positive breast cancer. It has also been used to prevent breast cancer in those at high risk.
Fadrozole (INN), sold under the brand name Afema (by Novartis), is a selective, nonsteroidal aromatase inhibitor which is or has been used in Japan for the treatment of breast cancer.
alpha,alpha-dihydroxydiethylstilbestrol · alpha,alpha-dihydroxydiethylstilbestrol, (R*,S*)-isomer · diethylstilbestrol vicinal diol
ESTRADIOL UNDECYLATE (3571-53-7)
Estradiol undecylate, or estradiol undecanoate, sold under the brand name Progynon Depot 100 among others, is a medication which has been used in the treatment of prostate cancer in men. It has also been used as a part of hormone therapy for transgender women. Although estradiol undecylate has been used in the past, it has mostly or fully been discontinued and hence is now mostly or fully no longer available.
hexestrol (84-16-2, 5635-50-7)
Hexestrol, (R-(R*,R*))-Isomer · Hexestrol, (R*,S*)-Isomer · Dihydrodiethylstilbestrol
Hexestrol (INN) (brand names Synestrol, Synoestrol, Estrifar, Estronal, numerous others), also known as hexanestrol, hexoestrol, and dihydrodiethylstilbestrol, is a synthetic nonsteroidal estrogen of the stilbestrol group related to diethylstilbestrol which was used to treat estrogen deficiency. Oil solution of hexestrol is still manufactured in Russia under trade name Синэстрол. Hexestrol has also been available and used in ester form, including as hexestrol diacetate, hexestrol dicaprylate, hexestrol diphosphate, and hexestrol dipropionate. Hexestrol has approximately 302% and 234% of the affinity of estradiol at the ERα and ERβ, respectively.
estradiol benzoate (50-50-0)
Eston-B · 17beta-estradiol-3-benzoate · estradiol 3-benzoate
Estradiol benzoate, sold under the brand name Progynon-B among others, is a medication which is used in hormone therapy such as for menopausal symptoms and in veterinary medicine. It is given by injection into muscle. Side effects of estradiol benzoate include breast tenderness, breast enlargement, nausea, headache, and fluid retention.
5alpha-Pregnane-3,20-dione · 3,20-Allopregnanedione, (5beta,13alpha,17alpha)-Isomer · 5 alpha-Pregnane-3,20-dione
Dihydrotestosterone · Androstanolone · Stanolone
Ogen · Genoral · piperazine estrone sulfate
Estropipate, also known as piperazine estrone sulfate and sold under the brand names Harmogen, Improvera, Ogen, Ortho-Est, and Sulestrex, among others, is an estrogen which is used mainly in menopausal hormone therapy in the treatment of menopausal symptoms. It is a salt of estrone sulfate and piperazine, and is hydrolyzed into estrone in the body.
ethinyl estradiol (57-63-6)
Estinyl · Ethinyloestradiol · Ethynyl Estradiol
Ethinylestriol (EE3), or 17α-ethynylestriol, also known as 17α-ethynylestra-1,3,5(10)-triene-3,16α,17β-triol, is a synthetic, steroidal estrogen that was never marketed. Nilestriol, the 3-cyclopentyl ether of ethinylestriol, is a prodrug of ethinylestriol, and is a more potent estrogen in comparison, but, similarly to ethinylestriol, was never marketed. Ethinylestriol has been found to reduce the risk of 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary cancer when given as a prophylactic in animal models, while other estrogens like ethinylestradiol and diethylstilbestrol were ineffective.
NORGESTIMATE (35189-28-7, 20799-27-3)
norgestrel oxime acetate
Norgestimate, sold under the brand names Ortho-Cyclen, Ortho Tri-Cyclen, Previfem, Sprintec, and Prefest among others, is a progestin that is used in combination with ethinylestradiol as an oral contraceptive and in combination with estradiol in menopausal hormone therapy. It is a prodrug, mainly of norelgestromin, but also of levonorgestrel in small amounts.
Estrovis · Ethinyl Estradiol 3 Cyclopentyl Ether · Ethinyl Estradiol 3-Cyclopentyl Ether
Quinestrol (INN, USAN, BAN) (brand names Agalacto-Quilea, Basaquines, Eston, Estrovis, Estrovister, Plestrovis, Qui-Lea), also known as ethinylestradiol 3-cyclopentyl ether (EE2CPE), is a synthetic, steroidal estrogen which is used in menopausal hormone therapy and occasionally to treat breast cancer and prostate cancer. It is a prodrug of ethinylestradiol (with cyclopentanol also being formed) with no intrinsic estrogenic activity of its own, and has a very long terminal half-life of more than 120 hours due to enhanced lipophilicity. Because of its much longer terminal half-life, quinestrol is two to three times as potent as ethinylestradiol.
Promegestone (INN) (brand name Surgestone), also known as 17α,21-dimethyl-δ9-19-norprogesterone or 17α,21-dimethyl-19-norpregna-4,9-diene-3,20-dione, is a progestin of the 19-norprogesterone group which was introduced in 1983 and is or has been marketed in France, Portugal, and Argentina. Indications include gynaecological conditions caused by luteal insufficiency, including premenopausal disorders, dysmenorrhea, and premenstrual syndrome. Promegestone has weak glucocorticoid activity, but does not bind to the androgen receptor or possess antimineralocorticoid activity.
Estriol · Epiestriol · (16alpha,17beta)-Estra-1,3,5(10)-Triene-3,16,17-Triol
Epiestriol (INN) (brand names Actriol, Arcagynil, Klimadoral), or epioestriol (BAN), also known as 16β-epiestriol or simply 16-epiestriol as well as 16β-hydroxy-17β-estradiol, is a minor and weak endogenous estrogen, and the 16β-epimer of estriol (which is 16α-hydroxy-17β-estradiol). Epiestriol is (or has previously been) used clinically in the treatment of acne. In addition to its estrogenic actions, epiestriol has been found to possess significant anti-inflammatory properties without glycogenic activity or immunosuppressive effects, an interesting finding that is in contrast to conventional anti-inflammatory steroids like hydrocortisone (a glucocorticoid).
2691-45-4 (69-14-7, 2691-45-4)
diethylaminoethoxyhexestrol · Coralgil · hexestrol bis(diethylaminoethyl ether), (R*,S*)-isomer