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Antiemetics

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nitrous oxide (10024-97-2)  
Laughing Gas  ·  Nitrogen Protoxide
Nitrous oxide, commonly known as laughing gas or nitrous, is a chemical compound, an oxide of nitrogen with the formula N 2O. At room temperature, it is a colorless non-flammable gas, with a slight metallic scent and taste. At elevated temperatures, nitrous oxide is a powerful oxidizer similar to molecular oxygen.
Chlorpromazine (34468-21-8, 50-53-3)  
Thorazine  ·  Chlorpromazine Hydrochloride  ·  Largactil
Chlorpromazine (CPZ), marketed under the trade names Thorazine and Largactil among others, is an antipsychotic medication. It is primarily used to treat psychotic disorders such as schizophrenia. Other uses include the treatment of bipolar disorder, attention deficit hyperactivity disorder, nausea and vomiting, anxiety before surgery, and hiccups that do not improve following other measures.
bupropion (34841-39-9, 34911-55-2)  
Wellbutrin  ·  Bupropion Hydrochloride  ·  Quomen
Bupropion is a medication primarily used as an antidepressant and smoking cessation aid. It is marketed as Wellbutrin and Zyban among other trade names. It is one of the most frequently prescribed antidepressants in the United States and Canada, although in many countries this is an off-label use.
Sevoflurane (28523-86-6)  
Sevoflurane (1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)propane; synonym, fluoromethyl hexafluoroisopropyl ether), is a sweet-smelling, nonflammable, highly fluorinated methyl isopropyl ether used as an inhalational anaesthetic for induction and maintenance of general anesthesia. After desflurane, it is the volatile anesthetic with the fastest onset and offset. It is one of the most commonly used volatile anesthetic agents, particularly for outpatient anesthesia, across all ages, as well as in veterinary medicine.
Dronabinol (308064-99-5, 6465-30-1, 1972-08-3)  
Tetrahydrocannabinol (THC) is a psychotropic cannabinoid (dronabinol, trade names Marinol and Syndros are a synthetic form of THC, approved by the FDA) and is the principal psychoactive constituent of cannabis. Its chemical name is (−)-trans-Δ⁹-tetrahydrocannabinol, and the term THC is used to refer to isomers as well. The pharmaceutical formulation dronabinol is available by prescription in the US, Canada, Germany, and New Zealand.
metoclopramide (364-62-5)  
Reglan  ·  Metoclopramide Hydrochloride  ·  Metaclopramide
Metoclopramide is a medication used mostly for stomach and esophageal problems. It is commonly used to treat and prevent nausea and vomiting, to help with emptying of the stomach in people with delayed stomach emptying, and to help with gastroesophageal reflux disease. It is also used to treat migraine headaches.
(+)-Isothujone (471-15-8)  
Thujone ( ( listen)) is a ketone and a monoterpene that occurs naturally in two diastereomeric forms: (−)-α-thujone and (+)-β-thujone. It has a menthol odor. Though it is best known as a chemical compound in the spirit absinthe, which contains only small quantities of thujone, it is unlikely to be responsible for absinthe's alleged psychedelic effects.
Isothujone (471-15-8)  
Thujone ( ( listen)) is a ketone and a monoterpene that occurs naturally in two diastereomeric forms: (−)-α-thujone and (+)-β-thujone. It has a menthol odor. Though it is best known as a chemical compound in the spirit absinthe, which contains only small quantities of thujone, it is unlikely to be responsible for absinthe's alleged psychedelic effects.
3-Thujanone (546-80-5, 1125-12-8)  
thujone  ·  beta-thujone, 1S-(1alpha,4beta,5alpha)-isomer  ·  alpha-thujone
Thujone ( ( listen)) is a ketone and a monoterpene that occurs naturally in two diastereomeric forms: (−)-α-thujone and (+)-β-thujone. It has a menthol odor. Though it is best known as a chemical compound in the spirit absinthe, which contains only small quantities of thujone, it is unlikely to be responsible for absinthe's alleged psychedelic effects.
ondansetron (99614-01-4, 99614-02-5)  
Zofran  ·  Ondansetron Hydrochloride  ·  GR38032F
Ondansetron, marketed under the brand name Zofran, is a medication used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, or surgery. It is also useful in gastroenteritis. It has little effect on vomiting caused by motion sickness.
alpha-Thujone (546-80-5, 59573-80-7)  
thujone  ·  beta-thujone, 1S-(1alpha,4beta,5alpha)-isomer  ·  3-isothujone
Thujone ( ( listen)) is a ketone and a monoterpene that occurs naturally in two diastereomeric forms: (−)-α-thujone and (+)-β-thujone. It has a menthol odor. Though it is best known as a chemical compound in the spirit absinthe, which contains only small quantities of thujone, it is unlikely to be responsible for absinthe's alleged psychedelic effects.
FLUPHENAZINE (69-23-8)  
Prolixin  ·  Fluphenazine Hydrochloride  ·  Flufenazin
Fluphenazine, sold under the brand names Prolixin among others, is an antipsychotic medication. It is used in the treatment of chronic psychoses such as schizophrenia, and appears to be about equal in effectiveness to low-potency antipsychotics like chlorpromazine. It is given by mouth, injection into a muscle, or just under the skin.
fluoxetine (54910-89-3)  
Prozac  ·  Fluoxetine Hydrochloride  ·  Sarafem
Fluoxetine, also known by trade names Prozac and Sarafem among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used for the treatment of major depressive disorder, obsessive–compulsive disorder (OCD), bulimia nervosa, panic disorder, and premenstrual dysphoric disorder. It may decrease the risk of suicide in those over the age of 65.
haloperidol (61788-97-4, 52-86-8)  
Haldol
Haloperidol, marketed under the trade name Haldol among others, is a typical antipsychotic medication. Haloperidol is used in the treatment of schizophrenia, tics in Tourette syndrome, mania in bipolar disorder, nausea and vomiting, delirium, agitation, acute psychosis, and hallucinations in alcohol withdrawal. It may be used by mouth, as an injection into a muscle, or intravenously.
thiethylperazine (1420-55-9, 1179-69-7)  
Torecan  ·  Norzine  ·  Novartis Brand of Thiethlperazine Maleate
Thiethylperazine (Torecan) is an antiemetic of the phenothiazine class. Though it was never licensed or used as an antipsychotic, it may have such effects. Thiethylperazine activates the transport protein ABCC1 that clears beta-amyloid from brains of mice.
Levomepromazine (7104-38-3, 60-99-1)  
Methotrimeprazine  ·  Levopromazine  ·  Tizercine
lorazepam (846-49-1)  
Ativan  ·  Tolid  ·  Lorazepam neuraxpharm Brand
Lorazepam, sold under the brand name Ativan among others, is a benzodiazepine medication. It is used to treat anxiety disorders, trouble sleeping, active seizures including status epilepticus, alcohol withdrawal, and chemotherapy induced nausea and vomiting, as well as for surgery to interfere with memory formation and to sedate those who are being mechanically ventilated. While it can be used for severe agitation, midazolam is usually preferred.
meclizine (569-65-3)  
Bonine  ·  Antivert  ·  Meclizine Hydrochloride
Meclizine (INN, or meclozine) is an antihistamine of the diphenylmethylpiperazine group considered to be an antiemetic. It is sold under the brand names Bonine, Bonamine, Antivert, Postafen, Sea Legs, and Dramamine II (Less Drowsy Formulation). Emesafene is a combination of meclizine (1/3) and pyridoxine (2/3).
granisetron (109889-09-0)  
Kytril  ·  Granisetron Hydrochloride  ·  BRL 43694
Granisetron is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata. It does not have much effect on vomiting due to motion sickness.
trimeprazine (84-96-8)  
Spansule  ·  Vallergan  ·  Panectyl
Alimemazine (INN), also known as trimeprazine,; brand names Nedeltran, Panectyl, Repeltin, Therafene, Theraligene, Theralen, Theralene, Vallergan, Vanectyl, and Temaril), commonly provided as a tartrate salt, is a phenothiazine derivative that is used as an antipruritic (it prevents itching from causes such as eczema or poison ivy, by acting as an antihistamine). It also acts as a sedative, hypnotic, and antiemetic for prevention of motion sickness. Although it is structurally related to drugs such as chlorpromazine, it is not used as an antipsychotic.
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