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Antineoplastic drugs

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Antineoplastic and immunomodulating drugs (313)
Pharmaceuticals (138)
Hormonal agents (102)
Systemic hormonal preparations (102)
Hormonal antineoplastic drugs (99)
Cyclic compounds (86)
Antineoplastic and immunomodulating drug (81)
Aromatase inhibitors (81)
DNA replication inhibitors (78)
Drugs acting on the genito-urinary system (53)
Sex hormones (53)
Experimental cancer drugs (45)
Halides (45)
Organohalides (43)
Alkylating antineoplastic agents (38)
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Antineoplastic antimetabolites (32)
Six-membered rings (32)
Topoisomerase inhibitors (31)
Aromatic compounds (26)
Blister agents (26)
Five-membered rings (26)
Organochlorides (23)
Nitrogen mustards (20)
Acids (18)
Organic acids (18)
Anthracyclines (17)
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VALPROIC ACID (99-66-1)  
Valproate  ·  Divalproex  ·  Depakote
Valproate (VPA), and its valproic acid, sodium valproate, and valproate semisodium forms, are medications primarily used to treat epilepsy and bipolar disorder and to prevent migraine headaches. It is useful for the prevention of seizures in those with absence seizures, partial seizures, and generalized seizures. It can be given intravenously or by mouth.
Mustard gas (505-60-2)  
Sulfur mustard, commonly known as mustard gas, is the prototypical substance of the sulfur-based family of cytotoxic and vesicant chemical warfare agents known as the sulfur mustards which have the ability to form large blisters on exposed skin and in the lungs. They have a long history of use as a blister-agent in warfare and along with organoarsenic compounds are the most well-studied such agents. Related chemical compounds with similar chemical structure and similar properties form a class of compounds known collectively as sulfur mustards or mustard agents.
endosulfan (959-98-8, 33213-65-9, 115-29-7)  
Thiodan  ·  beta-Endosulfan  ·  Thiodon
Endosulfan is an off-patent organochlorine insecticide and acaricide that is being phased out globally. The two isomers, endo and exo, are known popularly as I and II. Endosulfan sulfate is a product of oxidation containing one extra O atom attached to the S atom.
Resveratrol (501-36-0)  
Resveratrol (3,5,4′-trihydroxy-trans-stilbene) is a stilbenoid, a type of natural phenol, and a phytoalexin produced by several plants in response to injury or, when the plant is under attack by pathogens such as bacteria or fungi. Sources of resveratrol in food include the skin of grapes, blueberries, raspberries, mulberries. Although it is used as a dietary supplement, there is no good evidence that consuming resveratrol affects life expectancy or human health.
DICHLOROACETIC ACID (79-43-6)  
Bichloroacetic Acid  ·  Sodium Dichloroacetate  ·  Potassium Dichloroacetate
Dichloroacetic acid (DCA), sometimes called bichloroacetic acid (BCA), is the chemical compound with formula CHCl 2COOH. It is an acid, an analogue of acetic acid, in which 2 of the 3 hydrogen atoms of the methyl group have been replaced by chlorine atoms. Like the other chloroacetic acids, it has various practical applications.
Phenytoin (57-41-0, 630-93-3)  
Dilantin  ·  Diphenylhydantoin  ·  Phenytoin Sodium
Phenytoin (PHT), sold under the brand name Dilantin among others, is an anti-seizure medication. It is useful for the prevention of tonic-clonic seizures and partial seizures, but not absence seizures. The intravenous form is used for status epilepticus that does not improve with benzodiazepines.
rotenone (83-79-4)  
Rotenone is an odorless, colorless, crystalline isoflavone used as a broad-spectrum insecticide, piscicide, and pesticide. It occurs naturally in the seeds and stems of several plants, such as the jicama vine plant, and the roots of several members of Fabaceae. It was the first described member of the family of chemical compounds known as rotenoids.
Dronabinol (308064-99-5, 6465-30-1, 1972-08-3)  
Tetrahydrocannabinol (THC) is a psychotropic cannabinoid (dronabinol, trade names Marinol and Syndros are a synthetic form of THC, approved by the FDA) and is the principal psychoactive constituent of cannabis. Its chemical name is (−)-trans-Δ⁹-tetrahydrocannabinol, and the term THC is used to refer to isomers as well. The pharmaceutical formulation dronabinol is available by prescription in the US, Canada, Germany, and New Zealand.
Melatonin (8041-44-9, 73-31-4)  
Melatonin, also known as N-acetyl-5-methoxy tryptamine, is a hormone that is produced by the pineal gland in animals and regulates sleep and wakefulness. Melatonin is also produced in plants where it functions as a first line of defense against oxidative stress. In animals, melatonin is involved in the entrainment (synchronization) of the circadian rhythms including sleep-wake timing, blood pressure regulation, seasonal reproduction, and many others.
TRIADIMEFON (43121-43-3)  
Bayleton  ·  triadimenol  ·  azocene
Triadimefon is a fungicide used in agriculture to control various fungal diseases. As a seed treatment, it is used on barley, corn, cotton, oats, rye, sorghum, and wheat. In fruit it is used on pineapple and banana.
11-cis Retinoic Acid (302-79-4, 4759-48-2)  
Retinoic acid is a metabolite of vitamin A (retinol) that mediates the functions of vitamin A required for growth and development. Retinoic acid is required in chordate animals, which includes all higher animals from fish to humans. During early embryonic development, retinoic acid generated in a specific region of the embryo helps determine position along the embryonic anterior/posterior axis by serving as an intercellular signaling molecule that guides development of the posterior portion of the embryo.
Isotretinoin (4759-48-2, 97950-17-9)  
Accutane  ·  13 cis Retinoic Acid  ·  13-cis-Retinoic Acid
Isotretinoin, also known as 13-cis-retinoic acid (and colloquially referred to by its former brand name Accutane), is a medication primarily used to treat severe acne. Rarely, it is also used to prevent certain skin cancers (squamous-cell carcinoma), and in the treatment of other cancers. It is used to treat harlequin-type ichthyosis, a usually lethal skin disease, and lamellar ichthyosis.
Retinoic acid (302-79-4, 4759-48-2, 97950-17-9)  
Tretinoin  ·  Vitamin A Acid  ·  trans Retinoic Acid
Isotretinoin, also known as 13-cis-retinoic acid (and colloquially referred to by its former brand name Accutane), is a medication primarily used to treat severe acne. Rarely, it is also used to prevent certain skin cancers (squamous-cell carcinoma), and in the treatment of other cancers. It is used to treat harlequin-type ichthyosis, a usually lethal skin disease, and lamellar ichthyosis.
CAPECITABINE (154361-50-9)  
Capecitabine, sold under the brand name Xeloda among others, is a chemotherapy medication used to treat breast cancer, gastric cancer and colorectal cancer. For breast cancer it is often used together with docetaxel. It is taken by mouth.
diethylstilbestrol (6898-97-1, 56-53-1, 22610-99-7, 64-67-5)  
Stilbestrol  ·  Distilbène  ·  Stilbene Estrogen
palmitic acid (57-10-3, 67701-02-4)  
Sodium Palmitate  ·  Hexadecanoic Acid  ·  Calcium Palmitate
Palmitic acid, or hexadecanoic acid in IUPAC nomenclature, is the most common saturated fatty acid found in animals, plants and microorganisms. Its chemical formula is CH3(CH2)14COOH, and its C:D is 16:0. As its name indicates, it is a major component of the oil from the fruit of oil palms (palm oil).
5-Fluorouracil (51-21-8)  
Fluorouracil  ·  5FU  ·  Carac
Fluorouracil (5-FU), sold under the brand name Adrucil among others, is a medication used to treat cancer. By injection into a vein it is used for colon cancer, esophageal cancer, stomach cancer, pancreatic cancer, breast cancer, and cervical cancer. As a cream it is used for actinic keratosis and basal cell carcinoma.
9,13-Di-cis-retinoic acid (302-79-4, 5352-74-9, 4759-48-2)  
9,13-retinoic acid  ·  9-cis,13-cis-retinoic acid  ·  9,13-di-cis-RA
Isotretinoin, also known as 13-cis-retinoic acid (and colloquially referred to by its former brand name Accutane), is a medication primarily used to treat severe acne. Rarely, it is also used to prevent certain skin cancers (squamous-cell carcinoma), and in the treatment of other cancers. It is used to treat harlequin-type ichthyosis, a usually lethal skin disease, and lamellar ichthyosis.
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