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Aromatic amines

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Aromatic compounds (39)
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PhIP (105650-23-5)  
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
PhIP (2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) is one of the most abundant heterocyclic amines (HCAs) in cooked meat. PhIP is formed at high temperatures from the reaction between creatine or creatinine (found in muscle meats), amino acids, and sugar. PhIP formation increases with the temperature and duration of cooking and also depends on the method of cooking and the variety of meat being cooked.
Picloram (50655-56-6, 1918-02-1)  
Chloramp
Picloram is a systemic herbicide used for general woody plant control. It also controls a wide range of broad-leaved weeds, but most grasses are resistant. A chlorinated derivative of picolinic acid, picloram is in the pyridine family of herbicides.
Pomalidomide (19171-19-8)  
Pomalidomide (INN; marketed as Pomalyst in the U.S. and Imnovid in the EU and Russia) is a derivative of thalidomide marketed by Celgene. It is anti-angiogenic and also acts as an immunomodulator.
Trimethoprim (738-70-5)  
Proloprim  ·  Trimpex
Trimethoprim (TMP) is an antibiotic used mainly in the treatment of bladder infections. Other uses include for middle ear infections and travelers' diarrhea. With sulfamethoxazole or dapsone it may be used for Pneumocystis pneumonia in people with HIV/AIDS.
Lenalidomide (191732-72-6)  
Lenalidomide (trade name Revlimid) is a derivative of thalidomide introduced in 2004. It was initially intended as a treatment for multiple myeloma, for which thalidomide is an accepted therapeutic treatment. Lenalidomide has also shown efficacy in the class of hematological disorders known as myelodysplastic syndromes (MDS).
quinacrine (69-05-6, 78901-94-7, 83-89-6)  
Atabrine  ·  Mepacrine  ·  Atebrin
Mepacrine (INN), also called quinacrine (USAN) or by the trade name Atabrine, is a drug with several medical applications. It is related to chloroquine and mefloquine.
MALACHITE GREEN (569-64-2, 13425-25-7)  
basic green 4  ·  (4-(4-(dimethylamino) alpha-phenylbenzylidene)-2,5- cyclohexadien-1-ylidene)dimethylammonium chloride  ·  C.I. 42000
Malachite green is an organic compound that is used as a dyestuff and controversially as an antimicrobial in aquaculture. Malachite green is traditionally used as a dye for materials such as silk, leather, and paper. Despite its name the dye is not prepared from the mineral malachite, and the name just comes from the similarity of color.
pyrilamine (59-33-6, 91-84-9)  
Mepyramine  ·  Pyrilamine Maleate  ·  Anthisan
Mepyramine, also known as pyrilamine, is a first generation antihistamine, targeting the H1 receptor. However, it rapidly permeates the brain often causing drowsiness. It also has anticholinergic properties.
trimetrexate (52128-35-5)  
Trimetrexate is a quinazoline derivative. It is a dihydrofolate reductase inhibitor.
Torasemide (56211-40-6)  
Torasemide or torsemide is a pyridine-sulfonyl urea type loop diuretic mainly used in the management of edema associated with congestive heart failure. It is also used at low doses for the management of hypertension. It is marketed under the brand names Demadex, Diuver, and Examide.
minaprine (25905-77-5)  
Cantor  ·  Agr 1240  ·  minaprine dihydrochloride
Minaprine (INN, USAN, BAN) (brand names Brantur, Cantor) is a monoamine oxidase inhibitor antidepressant drug that was used in France for the treatment of depression until it was withdrawn from the market in 1996 because it caused convulsions. A study found that it acts as a reversible inhibitor of MAO-A (RIMA) in rats. In a study it has also been found to weakly inhibit acetylcholinesterase in rat brain (striatum) homogenates.
ETHIDIUM BROMIDE (1239-45-8)  
Ethidium  ·  Homidium Bromide  ·  Novidium
Ethidium bromide is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis. It is commonly abbreviated as "EtBr", which is also an abbreviation for bromoethane. When exposed to ultraviolet light, it will fluoresce with an orange colour, intensifying almost 20-fold after binding to DNA.
9-AMINOACRIDINE (90-45-9)  
Aminoacridine  ·  Aminacrine  ·  Aminoacridine Hydrochloride
9-Aminoacridine is a highly fluorescent dye used clinically as a topical antiseptic and experimentally as a mutagen, an intracellular pH indicator and a negative mode small molecule MALDI matrix.
RHODAMINE B (81-88-9)  
rhodamine B dihydride  ·  tetraethylrhodamine  ·  rhodamine B acetate
Rhodamine B is a chemical compound and a dye. It is often used as a tracer dye within water to determine the rate and direction of flow and transport. Rhodamine dyes fluoresce and can thus be detected easily and inexpensively with instruments called fluorometers.
Solvent green 3 (128-80-3)  
1,4-di-4-toluidinoanthraquinone  ·  cyanine green G base  ·  D and C Green #6
Quinizarine Green SS, also called Solvent Green 3, C.I. 61565, Oil Green G, D&C Green #6, is a green dye, an anthraquinone derivative. It has the appearance of a black powder with melting point of 220-221 °C.
Amrinone (60719-84-8)  
Inocor  ·  Amrinone LAW Brand  ·  Cordemcura
Amrinone (INN) or inamrinone (USAN, changed in 2000 to prevent confusion with amiodarone), trade name Inocor, is a pyridine phosphodiesterase 3 inhibitor. It is a drug that may improve the prognosis in patients with congestive heart failure. Amrinone has been shown to increase the contractions initiated in the heart by high gain calcium induced calcium release (CICR).
LUMINOL (521-31-3)  
5-amino-2,3-dihydrophthalazine-1,4-dione  ·  521-31-3
Luminol (C8H7N3O2) is a chemical that exhibits chemiluminescence, with a blue glow, when mixed with an appropriate oxidizing agent. Luminol is a white-to-pale-yellow crystalline solid that is soluble in most polar organic solvents, but insoluble in water. Forensic investigators use luminol to detect trace amounts of blood at crime scenes, as it reacts with the iron in hemoglobin.
3,4-DIAMINOPYRIDINE (54-96-6)  
amifampridine  ·  Firdapse  ·  amifampridine phosphate
Amifampridine (pyridine-3,4-diamine, 3,4-diaminopyridine, 3,4-DAP) is used as a drug, predominantly in the treatment of a number of rare muscle diseases. The free base form of the drug has been used to treat congenital myasthenic syndromes and Lambert–Eaton myasthenic syndrome (LEMS) through compassionate use programs since the 1990s and was recommended as a first line treatment for LEMS in 2006, using ad hoc forms of the drug, since there was no marketed form. Around 2000 doctors at Assistance Publique – Hôpitaux de Paris created a phosphate salt form, which was developed through a series of companies ending with BioMarin Pharmaceutical which obtained European approval in 2009 under the trade name Firdapse, and which licensed the US rights to Catalyst Pharmaceuticals in 2012.
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