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Bicyclic compounds, Amines

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Bases (chemistry) (1)
Cyclic compounds (1)
Pharmaceuticals (1)
Polycyclic organic compounds (1)

mecamylamine (60-40-2, 826-39-1)  
Mecamylamine (INN, BAN; or mecamylamine hydrochloride (USAN); brand names Inversine, Vecamyl) is a non-selective, non-competitive antagonist of the nicotinic acetylcholine receptors (nAChRs) that was introduced in the 1950s as an antihypertensive drug. In the United States, it was voluntarily withdrawn from the market in 2009 but was brought to market in 2013 as Vecamyl and eventually was marketed by Turing Pharmaceuticals. Chemically, mecamylamine is a secondary aliphatic amine, with a pKaH of 11.2

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