C3H9NO, Neuroprotective agents
Organic acids (1)
Sulfonic acids (1)
AK Scientific (1)
Sigma Aldrich (1)
TCI Chemicals (1)
3-APS · 3-aminopropanesulfonic acid · 3-amino-1-propanesulfonic acid
Homotaurine (3-amino-1-propanesulfonic acid (3-APS) or tramiprosate (INN)) is a synthetic organic compound. It is analogous to taurine, but with an extra carbon in its chain. It has GABAergic activity, apparently by mimicking GABA, which is it resembles.
Thymoquinone (73940-92-8, 490-91-5)
2-methyl-5-isopropyl-p-benzoquinone · 2-isopropyl-5-methylbenzoquinone · dihydrothymoquinone
Thymoquinone is a phytochemical compound found in the plant Nigella sativa. It is also found in select cultivated Monarda fistulosa plants grown and steam distilled in the USA producing an essential oil. In laboratory experiments in cells and in animals, it has shown anti-inflammatory and anti-oxidant effects, and has been studied in models of cardiovascular diseases and diabetes, neurodegenerative diseases and stroke, and cancer.
Crocin (94238-00-3, 39465-00-4, 42553-65-1)
Crocin is a carotenoid chemical compound that is found in the flowers crocus and gardenia. Crocin is the chemical primarily responsible for the color of saffron. Chemically, crocin is the diester formed from the disaccharide gentiobiose and the dicarboxylic acid crocetin.
Carnosine · Carnosine Hydrochloride · Carnosine, (D-His)-Isomer
Carnosine (beta-alanyl-L-histidine), featuring the characteristic Imidazole-ring, is a dipeptide molecule, made up of the amino acids beta-alanine and histidine. It is highly concentrated in muscle and brain tissues. Carnosine and carnitine were discovered by Russian chemist Vladimir Gulevich.
Riluzole (marketed as Rilutek and Teglutik) is a drug used to treat amyotrophic lateral sclerosis. Riluzole delays the onset of ventilator-dependence or tracheostomy in selected patients and may increase survival by approximately two to three months. Riluzole is available in a tablet and liquid form.
2,5-dihydroxy-3-undecyl-1,4-benzoquinone · potassium embelate
2-phenyl-1,2-benzoisoselenazol-3(2H)-one · RP 60931 · DR 3305
Ebselen (also called PZ 51, DR3305, and SPI-1005), is a synthetic organoselenium drug molecule with anti-inflammatory, anti-oxidant and cytoprotective activity. It acts as a mimic of glutathione peroxidase and can also react with peroxynitrite. It is being investigated as a possible treatment for reperfusion injury and stroke, hearing loss and tinnitus, and bipolar disorder.
Melatonin (8041-44-9, 73-31-4)
Melatonin, also known as N-acetyl-5-methoxy tryptamine, is a hormone that is produced by the pineal gland in animals and regulates sleep and wakefulness. Melatonin is also produced in plants where it functions as a first line of defense against oxidative stress. In animals, melatonin is involved in the entrainment (synchronization) of the circadian rhythms including sleep-wake timing, blood pressure regulation, seasonal reproduction, and many others.
Baicalin is a flavone glycoside. It is the glucuronide of baicalein.
berbamine hydrochloride · berbamine monohydrochloride · berbamine, (1'beta)-isomer
HWA 285 · 1-(5'-oxohexyl)-3-methyl-7-propylxanthine · HWA-285
Propentofylline (HWA 285) is a xanthine derivative with purported neuroprotective effects.
MINOCYCLINE HYDROCHLORIDE (13614-98-7)
Cyclops · Minocycline · Minocin
lycorine (2188-68-3, 476-28-8)
lycorine hydrochloride, (1alpha,2beta)-isomer · 2,4,5,7,12b,12c-hexahydro-1H-(1,3)dioxolo- (4,5-j)pyrrolo(3,2,1-de)phenanthridine-1,2-diol
Lycorine is a toxic crystalline alkaloid found in various Amaryllidaceae species, such as the cultivated bush lily (Clivia miniata), surprise lilies (Lycoris), and daffodils (Narcissus). It may be highly poisonous, or even lethal, when ingested in certain quantities. Regardless, it is sometimes used medicinally, a reason why some groups may harvest the very popular Clivia miniata.
Honokiol is a lignan isolated from the bark, seed cones, and leaves of trees belonging to the genus Magnolia. It has been identified as one the chemical compounds in some traditional eastern herbal medicines along with magnolol, 4-O-methylhonokiol, and obovatol.
Nobiletin is a flavonoid isolated from citrus peels. It is an O-methylated flavone that has the activity to rescue bulbectomy-induced memory impairment.
isoandrographolide · 17-hydro-9-dehydro-andrographolide
Andrographolide is a labdane diterpenoid that has been isolated from the stem and leaves of Andrographis paniculata. Andrographolide is an extremely bitter substance. Andrographolide has been studied for its effects on cell signaling, immunomodulation, and stroke.
Myricitrin is a plant compound, the 3-O-α-L-rhamnopyranoside of myricetin.
Parthenolide is a sesquiterpene lactone of the germacranolide class which occurs naturally in the plant feverfew (Tanacetum parthenium), after which it is named. It is found in highest concentration in the flowers and fruit.
MEMANTINE HYDROCHLORIDE (41100-52-1)
Memantine · Namenda · D 145
Memantine is used to treat moderate to severe Alzheimer's disease. It acts on the glutamatergic system by blocking NMDA receptors. It was first synthesized by Eli Lilly and Company in 1968 as a potential agent to treat diabetes; the NMDA activity was discovered in the 1980s.