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C4H6, Antihistamines

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Pizotifen (15574-96-6)  
Sandomigran  ·  Pizotyline  ·  BC 105
Pizotifen (INN) or pizotyline (USAN), trade name Sandomigran, is a benzocycloheptene-based drug used as a medicine, primarily as a preventative to reduce the frequency of recurrent migraine headaches.

Related Results:
mequitazine (147780-50-5, 29216-28-2)  
Mircol  ·  Primalan  ·  mequitazine hydrochloride
Mequitazine (trade name Primalan) is an H1 antagonist and anticholinergic of the phenothiazine chemical class. It is used to treat allergies and rhinitis.
chlorpheniramine (113-92-8, 32188-09-3, 132-22-9)  
Chlorpheniramine Maleate  ·  Teldrin  ·  Piriton
Chlorphenamine (also known as chlorpheniramine, CP, or CPM) is a first-generation antihistamine used in the prevention of the symptoms of allergic conditions such as rhinitis and urticaria. Its sedative effects are relatively weak compared to other first-generation antihistamines. Chlorphenamine is one of the most commonly used antihistamines in small-animal veterinary practice.
azelastine (58581-89-8)  
Astelin  ·  Optivar  ·  azelastine hydrochloride
Azelastine is a potent, second-generation, selective, histamine antagonist (histamine-H1-receptor antagonist) used as a first line therapy of mild intermittent, moderate/severe intermittent and mild persistent rhinitis (new classification system for rhinitis). Azelastine has been formulated both as a nasal spray and as eye drops and are available worldwide under many brand names.
clemastine (15686-51-8)  
Clemastine, also known as meclastin, is an antihistamine and anticholinergic. Unlike loratadine or fexofenadine, clemastine is a sedating antihistamine; however, it exhibits fewer other side effects than most of the widely used antihistamines. Clemastine is also classified as an antipruritic (i.e., it stops itching).
astemizole (68844-77-9)  
Hismanal  ·  Romadin  ·  Elfar Brand of Astemizole
Astemizole (marketed under the brand name Hismanal, developmental code R43512) was a second-generation antihistamine drug that has a long duration of action. Astemizole was discovered by Janssen Pharmaceutica in 1977. It has been withdrawn from the market in most countries because of rare but potentially fatal side effects (QTc interval prolongation and related arrhythmias due to hERG channel blockade).
Azatadine dimaleate (3978-86-7)  
azatadine  ·  Optimine  ·  azatadine maleate
AZATADINE (3964-81-6)  
Azatadine (Optimine) is a first-generation antihistamine and anticholinergic that was launched Schering-Plough in 1973. It was patented in 1967. It has been succeeded by other antihistamines and marketing approvals have been widely withdrawn.
AZELASTINE HYDROCHLORIDE (79307-93-0, 37932-96-0)  
azelastine  ·  Astelin  ·  Optivar
Azelastine is a potent, second-generation, selective, histamine antagonist (histamine-H1-receptor antagonist) used as a first line therapy of mild intermittent, moderate/severe intermittent and mild persistent rhinitis (new classification system for rhinitis). Azelastine has been formulated both as a nasal spray and as eye drops and are available worldwide under many brand names.
BROMPHENIRAMINE (86-22-6)  
Dimetane  ·  Brompheniramine Maleate  ·  Chlorphed
Brompheniramine (Bromfed, Dimetapp, Bromfenex, Dimetane, BPN, Lodrane), commonly marketed as its salt brompheniramine maleate, is an antihistamine drug of the propylamine (alkylamine) class. It is readily available over the counter and is indicated for the treatment of the symptoms of the common cold and allergic rhinitis, such as runny nose, itchy eyes, watery eyes, and sneezing. It is a first-generation antihistamine.
terfenadine (50679-08-8)  
Seldane  ·  Terfenidine  ·  Sigma Tau Brand of Terfenadine
Terfenadine is an antihistamine formerly used for the treatment of allergic conditions. It was brought to market by Hoechst Marion Roussel (now Sanofi-Aventis) and was marketed under various brand names, including Seldane in the United States, Triludan in the United Kingdom, and Teldane in Australia. It was superseded by fexofenadine in the 1990s due to the risk of a particular type of disruption of the electrical rhythms of the heart (specifically cardiac arrhythmia caused by QT interval prolongation) and has been withdrawn from markets worldwide.
KETOTIFEN FUMARATE (34580-14-8)  
Ketotifen  ·  Zaditen  ·  Ketotiphen
Ketotifen, sold under the brand name Zaditor among others, is a first-generation noncompetitive H1-antihistamine and mast cell stabilizer. It is most commonly sold as a salt with fumaric acid, ketotifen fumarate, and is available in two forms. In its ophthalmic form, it is used to treat allergic conjunctivitis.
oxatomide (60607-34-3)  
KW-4354  ·  R 35443  ·  oxatimide
Oxatomide, sold under the brand name Tinset among others, is a first-generation antihistamine of the diphenylmethylpiperazine family which is marketed in Europe, Japan, and a number of other countries. It was discovered at Janssen Pharmaceutica in 1975. Oxatomide lacks any anticholinergic effects.
Hydroxyzine dihydrochloride (2192-20-3)  
Hydroxyzine  ·  Vistaril  ·  Atarax
Hydroxyzine, sold under the brand names Atarax and Vistaril among others, is a first-generation antihistamine. It was first synthesized by Union Chimique Belge in 1956 and was marketed by Pfizer in the United States later the same year and is still widely used today. Because of its antihistamine effects, it can be used for the treatment of severe cases of itching, hyperalgesia, and motion sickness-induced nausea; it has also been used in some cases to relieve the effects of opioid withdrawal.
Hydroxyzine pamoate (10246-75-0)  
Hydroxyzine  ·  Vistaril  ·  Atarax
CLEMASTINE FUMARATE (14976-57-9, 15686-51-8)  
Clemastine  ·  Tavist  ·  HS 592
Clemastine, also known as meclastin, is an antihistamine and anticholinergic. Unlike loratadine or fexofenadine, clemastine is a sedating antihistamine; however, it exhibits fewer other side effects than most of the widely used antihistamines. Clemastine is also classified as an antipruritic (i.e., it stops itching).
Brompheniramine maleate (980-71-2)  
Brompheniramine  ·  Dimetane  ·  Chlorphed
Brompheniramine (Bromfed, Dimetapp, Bromfenex, Dimetane, BPN, Lodrane), commonly marketed as its salt brompheniramine maleate, is an antihistamine drug of the propylamine (alkylamine) class. It is readily available over the counter and is indicated for the treatment of the symptoms of the common cold and allergic rhinitis, such as runny nose, itchy eyes, watery eyes, and sneezing. It is a first-generation antihistamine.
cromolyn (16110-51-3)  
Cromolyn Sodium  ·  Cromoglycate  ·  Intal
Cromoglicic acid (INN) (also referred to as cromolyn (USAN), cromoglycate (former BAN), or cromoglicate) is traditionally described as a mast cell stabilizer, and is commonly marketed as the sodium salt sodium cromoglicate or cromolyn sodium. This drug prevents the release of inflammatory chemicals such as histamine from mast cells. Because of their convenience (and perceived safety), leukotriene receptor antagonists have largely replaced it as the non-corticosteroid treatment of choice in the treatment of asthma.
loratadine (79794-75-5)  
Claritin  ·  Alavert  ·  Clarium
Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. This includes allergic rhinitis (hay fever) and hives. It is also available in combination with pseudoephedrine, a decongestant, known as loratadine/pseudoephedrine.
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