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Similar to 6,7-Dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline
, D1-receptor agonists

Categories

Alkaloids (1)
Antiparkinsonian agents (1)
D2 antagonists (1)
Dopamine agonists (1)
Dopamine antagonists (1)
Drugs acting on the nervous system (1)
Psychoactive drugs (1)

D,L-Stepholidine (16562-14-4)  
(−)-Stepholidine is a protoberberine alkaloid found in the plant Stephania intermedia. Stepholidine activity includes dual D2 receptor antagonist and D1 receptor agonist, and has shown antipsychotic activity in animal studies.

Related Results:
XANOMELINE (131986-45-3)  
Xanomeline (LY-246,708; Lumeron, Memcor) is a muscarinic acetylcholine receptor agonist with reasonable selectivity for the M1 and M4 subtypes, though it is also known to act as a M5 receptor antagonist. It has been studied for the treatment of both Alzheimer's disease and schizophrenia, particularly the cognitive and negative symptoms, although gastrointestinal side effects led to a high drop-out rate in clinical trials. Despite this, xanomeline has been shown to have reasonable efficacy for the treatment of schizophrenia symptoms, and one recent human study found robust improvements in verbal learning and short-term memory associated with xanomeline treatment.
Spiroxatrine (1054-88-2)  
Spiroxatrine is a drug which acts as a selective antagonist at both the 5-HT1A receptor and the α2C adrenergic receptor. It is an analog of spiperone and also has some dopamine antagonist effects.
Efaroxan (89197-32-0)  
Efaroxan is an α2-adrenergic receptor antagonist and antagonist of the imidazoline receptor.
Quinelorane (97466-90-5, 97548-97-5)  
Quinelorane is a drug which acts as a dopamine agonist for the D2 and D3 receptor.
(+/-)-Epibatidine (140111-52-0)  
Epibatidine is a putative alkaloid that is secreted by the Ecuadoran frog Epipedobates anthonyi. It was discovered by John W. Daly in 1974, but its structure was not fully elucidated until 1992.
cirazoline (59939-16-1)  
LD-3098  ·  cirazoline monohydrochloride  ·  2-(2'-cyclopropylphenoxymethyl)imidazoline hydrochloride
Cirazoline is a full agonist at the α1A adrenergic receptor, a partial agonist at both the α1B and α1D adrenergic receptors, and a nonselective antagonist to the α2 adrenergic receptor. It is believed that this combination of properties could make cirazoline an effective vasoconstricting agent. Cirazoline has also been shown to decrease food intake in rats, purportedly through activation of α1 adrenoceptors in the paraventricular nucleus in the hypothalamus of the brain.
ritanserin (87051-43-2)  
Ritanserin (INN, USAN, BAN) is a serotonin receptor antagonist which was never marketed for clinical use but has been used in scientific research.
3-Apmpa (127729-35-5)  
SKF-97,541 is a compound used in scientific research which acts primarily as a selective GABAB receptor agonist. It has sedative effects in animal studies and is widely used in research into potential treatment of various types of drug addiction.
QUINPIROLE (74196-92-2, 80373-22-4)  
Quinpirole is a psychoactive drug and research chemical which acts as a selective D2 and D3 receptor agonist. It is used in scientific research. Quinpirole has been shown to increase locomotion and sniffing behavior in mice treated with it.
Ro 48-8071 (161582-11-2)  
Ro 48-8071hydrochloride  ·  (4'-(6-allylmethylaminohexyloxy)-2'-fluorophenyl)-4-(4-bromophenyl)methanone fumarate  ·  Ro-48-8071
CGP-20712A (137888-49-4)  
2-hydroxy-5-(2-(hydroxy-3-(4-((1-methyl-4-trifluoromethyl)-1H-imidazol-2-yl)phenoxy)propyl)aminoethoxy)benzamide  ·  CGP-20712  ·  CGP 20712A
isoguvacine (64603-90-3)  
isoguvacine hydrochloride  ·  isoguvacine hydrobromide
Isoguvacine is a GABAA receptor agonist used in scientific research.
Emonapride (70325-83-6)  
YM 09151-M  ·  YM-09151-2  ·  nemonapride
Nemonapride (エミレース, Emilace (JP)) is an atypical antipsychotic approved in Japan for the treatment of schizophrenia. It was launched by Yamanouchi in 1991. Nemonapride acts as a D2 and D3 receptor antagonist, and is also a potent 5-HT1A receptor agonist.
clobenpropit (145231-45-4)  
S-(3-(4(5)-imidazolyl))propyl-N-(4-chlorobenzyl)isothiourea  ·  VUF-9153  ·  VUF 9153
Clobenpropit is a histamine H3 receptor antagonist. It has neuroprotective effects via stimulation of GABA release in the brain.
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