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Drugs acting on the nervous system (9)
Pharmaceuticals (8)
Psychoactive drugs (8)
Tryptamines (8)
Psychedelic drugs (4)
Psychedelic tryptamines (4)
Designer drugs (3)
Melatonergic (3)
Melatonin (3)
Melatonin receptor agonists (3)
Tryptamine alkaloids (3)
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Antineoplastic drugs (1)
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Hallucinogen (1)
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Sigma Aldrich (31)
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Melatonin (8041-44-9, 73-31-4)  
Melatonin, also known as N-acetyl-5-methoxy tryptamine, is a hormone that is produced by the pineal gland in animals and regulates sleep and wakefulness. Melatonin is also produced in plants where it functions as a first line of defense against oxidative stress. In animals, melatonin is involved in the entrainment (synchronization) of the circadian rhythms including sleep-wake timing, blood pressure regulation, seasonal reproduction, and many others.
serotonin (50-67-9)  
Hydroxytryptamine  ·  Enteramine  ·  5 Hydroxytryptamine
In biology, a pathogen (Greek: πάθος pathos "suffering, passion" and -γενής -genēs "producer of") in the oldest and broadest sense is anything that can produce disease; the term came into use in the 1880s. Typically the term is used to describe an infectious agent such as a virus, bacterium, protozoa, prion, a fungus, or other micro-organism. The scientific study of pathogens is called Pathology.
Psilocybine (520-52-5)  
Psilocybin  ·  Psilocibin
Psilocybin ( sy-lə-SY-bin) is a naturally occurring psychedelic prodrug compound produced by more than 200 species of mushrooms, collectively known as psilocybin mushrooms. Psilocybin evolved in mushrooms from its ancestor, muscarine, some 20 million years ago. The most potent are members of the genus Psilocybe, such as P. azurescens, P. semilanceata, and P. cyanescens, but psilocybin has also been isolated from about a dozen other genera.
5-Hydroxyindole-3-acetic acid (54-16-0)  
Hydroxyindoleacetic Acid  ·  5-Hydroxy-3-Indoleacetic Acid  ·  5 Hydroxyindolamine Acetic Acid
5-Hydroxyindoleacetic acid (5-HIAA) is the main metabolite of serotonin. In chemical analysis of urine samples, 5-HIAA is used to determine serotonin levels in the body.
N-Acetyl-5-hydroxytryptamine (1210-83-9)  
N-acetylserotonin  ·  N-acetylhydroxytryptamine
N-Acetylserotonin (NAS), also known as normelatonin, is a naturally occurring chemical precursor and intermediate in the endogenous production of melatonin from serotonin. It also has biological activity in its own right, including acting as a melatonin receptor agonist, an agonist of the TrkB, and having antioxidant effects.
5-Hydroxytryptophol (154-02-9)  
Bufotenine (487-93-4)  
Mappin  ·  Bufotenin  ·  Dimethylserotonin
Bufotenin (5-HO-DMT, N,N-dimethyltryptamine, bufotenine) is a tryptamine related to the neurotransmitter serotonin. It is an alkaloid found in the skin of some species of toads; in mushrooms, higher plants, and mammals. The name bufotenin originates from the Bufo genus of toads, which includes several species of psychoactive toads, most notably Incilius alvarius, that secrete bufotoxins from their parotoid glands.
3-Indoleacetonitrile (771-51-7)  
5-Methoxytryptophol (712-09-4)  
N,N-Dimethyl-5-methoxytryptamine (1019-45-0)  
Methoxydimethyltryptamine  ·  5 Methoxy N,N Dimethyltryptamine  ·  N,N Dimethyl 5 Methoxytryptamine
5-MeO-DMT (5-methoxy-N,N-dimethyltryptamine) is a psychedelic of the tryptamine class. It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado River toad. Like its close relatives DMT and bufotenin (5-HO-DMT), it has been used as an entheogen in South America.
Methoxytryptamine  ·  Meksamine  ·  Mexamine
5-Methoxytryptamine (5-MT), also known as mexamine, is a tryptamine derivative closely related to the neurotransmitters serotonin and melatonin. 5-MT has been shown to occur naturally in the body in low levels. It is biosynthesized via the deacetylation of melatonin in the pineal gland.
PSILOCIN (520-53-6)  
(3-(2-dimethylamino)ethyl)indol-4-ol  ·  psilocin tartrate (1:1)  ·  psilocin hydrochloride
Psilocin (also known as 4-HO-DMT, psilocine, psilocyn, or psilotsin) is a substituted tryptamine alkaloid and a serotonergic psychedelic substance. It is present in most psychedelic mushrooms together with its phosphorylated counterpart psilocybin. Psilocin is a Schedule I drug under the Convention on Psychotropic Substances.
6-HYDROXYMELATONIN (2208-41-5)  
6-Hydroxymelatonin (6-OHM) is a naturally occurring, endogenous, major active metabolite of the neurotransmitter melatonin. Similar to melatonin, 6-OHM is a full agonist of the MT1 and MT2 receptors. It is also an antioxidant and neuroprotective, and is even more potent in this regard relative to melatonin.
4021-34-5 (4021-34-5)  
5-methoxy-diisopropyltryptamine (5-MeO-DiPT), sometimes called "Foxy", is a psychedelic tryptamine. 5-MeO-DiPT is orally active, and dosages between 6–20 mg are commonly reported. Many users note an unpleasant body load accompanies higher dosages.
N-Methylserotonin (1134-01-6)  
N-Methylserotonin is a tryptamine alkaloid. Chemically, it is a derivative of serotonin in which a methyl group resides at its alkyl amine. It is also called Nω-methylserotonin (Nω-methyl-5-hydroxytryptamine) to distinguish it from tryptamine-derived compounds in which a methyl group is bonded to the nitrogen atom of the indole group.
5-Benzyloxytryptamine (52055-23-9, 20776-45-8)  
5-Benzyloxytryptamine (5-BT), is a tryptamine derivative which acts as an agonist at the 5-HT1D, 5-HT2 and 5-HT6 serotonin receptors.
5-Methoxy-alpha-methyltryptamine (1137-04-8)  
5-MeO-aMT or 5-methoxy-α-methyltryptamine, α,O-Dimethylserotonin (Alpha-O) is a potent psychedelic tryptamine. It is soluble in ethanol.
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