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CYP17A1 inhibitors

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Antiandrogens (15)
Antiglucocorticoids (15)
Drugs acting on the genito-urinary system (15)
Hormonal agents (15)
Sex hormones (15)
Systemic hormonal preparations (15)
Antineoplastic and immunomodulating drugs (12)
Antineoplastic drugs (11)
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Aromatase inhibitors (9)
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Ethers (5)
Anti-diabetic drugs (4)
Chloroarenes (4)
Drugs acting on the gastrointestinal system and metabolism (4)
PPAR agonists (4)
Thiazolidinediones (4)
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Pioglitazone (111025-46-8)  
Actos  ·  pioglitazone hydrochloride  ·  U72,107A
Pioglitazone (brand name Actos) is a prescription drug of the thiazolidinedione (TZD) class with hypoglycemic (antihyperglycemic, antidiabetic) action to treat diabetes. While pioglitazone does decrease blood sugar levels, studies on the main cardiovascular outcomes have not yielded statistically significant results. Its cardiovascular safety profile compares favorably with that of rosiglitazone, which was withdrawn from some markets after concerns about an increased risk of cardiac events.
rosiglitazone (122320-73-4)  
Rosiglitazone (trade name Avandia) is an antidiabetic drug in the thiazolidinedione class. It works as an insulin sensitizer, by binding to the PPAR in fat cells and making the cells more responsive to insulin. It is marketed by the pharmaceutical company GlaxoSmithKline (GSK) as a stand-alone drug or for use in combination with metformin or with glimepiride.
clotrimazole (23593-75-1)  
Lotrimin  ·  Mycelex  ·  Canesten
Clotrimazole, sold under the brand name Canesten among others, is an antifungal medication. It is used to treat vaginal yeast infections, oral thrush, diaper rash, pityriasis versicolor, and types of ringworm including athlete's foot and jock itch. It can be taken by mouth or applied as a cream to the skin or in the vagina.
miconazole (22916-47-8)  
Monistat  ·  Miconazole Nitrate  ·  Brentan
Miconazole, sold under the brand name Monistat among others, is an antifungal medication used to treat ring worm, pityriasis versicolor, and yeast infections of the skin or vagina. It is applied to the skin or vagina as a cream or ointment. Common side effects include itchiness or irritation of the area in which it was applied.
troglitazone (97322-87-7)  
Troglitazone (Rezulin, Resulin, Romozin, Noscal) is an antidiabetic and anti-inflammatory drug, and a member of the drug class of the thiazolidinediones. It was prescribed for patients with diabetes mellitus type 2. It was developed by Daiichi Sankyo (Japan).
flutamide (13311-84-7)  
Eulexin  ·  Euflex  ·  SCH 13521
Flutamide, sold under the brand name Eulexin among others, is a nonsteroidal antiandrogen (NSAA) which is used primarily to treat prostate cancer. It is also used in the treatment of androgen-dependent conditions like acne, excessive hair growth, and high androgen levels in women. It is taken by mouth, usually three times per day.
nilutamide (63612-50-0)  
Nilandron  ·  Anandron  ·  RU 23908
Nilutamide, sold under the brand names Nilandron and Anandron, is a nonsteroidal antiandrogen (NSAA) which is used in the treatment of prostate cancer. It has also been studied as a component of feminizing hormone therapy for transgender women and to treat acne and seborrhea in women. It is taken by mouth.
econazole (27220-47-9, 68797-30-8)  
Econazole Nitrate  ·  GynoPevaril  ·  Gyno Pervaryl 150
Econazole (commonly used as the nitrate salt) is an antifungal medication of the imidazole class. It is sold under the brand names Spectrazole (United States) and Ecostatin (Canada), among others. It is a component of Pevisone and Ecoderm-TA (econazole/triamcinolone).
bifonazole (60628-96-8)  
Bifon  ·  Mycospor  ·  Bay H 4502
Bifonazole (trade name Canespor among many others) is an imidazole antifungal drug used in form of ointments. There are also combinations with carbamide for the treatment of onychomycosis.
Isoconazole (27523-40-6)  
Icaden  ·  isoconazole nitrate  ·  Gyno Icaden
Isoconazole is an azole antifungal drug and could inhibit gram positive bacteria. Nigerian and British medical researchers found that for foot and vaginal infections, isoconazole has a similar effectiveness to clotrimazole. Isoconazole nitrate may be used in combination with corticosteroid diflucortolone to increase its bioavailability.
Liarozole (115575-11-6)  
Liarozole is a retinoic acid metabolism-blocking drug and aromatase inhibitor.
Bifluranol (34633-34-6)  
Bifluranol (INN, BAN; brand name Prostarex; former developmental code name BX-341) is a synthetic nonsteroidal estrogen of the stilbestrol group related to diethylstilbestrol that has been used as an antiandrogen in the United Kingdom in the treatment of benign prostatic hyperplasia. It is a polyfluorinated biphenyl that is related to polybrominated and polychlorinated biphenyls and diethylstilbestrol. The drug is described as a weak estrogen, and possesses about one-eighth the potency of diethylstilbestrol.

Related Results:
Protein kinase inhibitor H-8 (84478-11-5)  
H8 protein kinase inhibitor  ·  N-(2-(methylamino)ethyl)-5-isoquinolinesulfonamide  ·  H-8 protein kinase inhibitor
AEIQS (84468-17-7)  
N-(2-aminoethyl)-5-isoquinolinesulfonamide  ·  H-9  ·  protein kinase C inhibitor H-9
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