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Cyclopropanes

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Ciprofloxacin (85721-33-1)  
Cipro  ·  Ciprofloxacin Hydrochloride  ·  Ciprofloxacin Monohydrochloride Monohydrate
Ciprofloxacin is an antibiotic used to treat a number of bacterial infections. This includes bone and joint infections, intra abdominal infections, certain type of infectious diarrhea, respiratory tract infections, skin infections, typhoid fever, and urinary tract infections, among others. For some infections it is used in addition to other antibiotics.
CYFLUTHRIN (68359-37-5)  
cyano(4-fluoro-3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane carboxylate  ·  OMS 2012  ·  beta-cyfluthrin
naltrexone (16590-41-3, 16676-29-2)  
ReVia  ·  Trexan  ·  Naltrexone Hydrochloride
Naltrexone, sold under the brand names Revia and Vivitrol among others, is a medication primarily used to manage alcohol dependence and opioid dependence. In opioid dependence, it should not be started until people are detoxified. It is taken by mouth or by injection into a muscle.
Cyromazine (66215-27-8)  
cyromazine dihydrochloride  ·  Vetrazin  ·  CGA-72662
Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects.
abacavir (136470-78-5, 188062-50-2, 79804-71-0)  
Abacavir (ABC) is a medication used to prevent and treat HIV/AIDS. Similar to other nucleoside reverse transcriptase inhibitors (NRTIs), abacavir is used together with other HIV medications, and is not recommended by itself. It is taken by mouth as a tablet or solution and may be used in children over the age of three months.
tranylcypromine (3721-26-4, 155-09-9)  
Parnate  ·  Tranylcypromine Sulfate  ·  Jatrosom
Tranylcypromine (contracted from trans-2-phenylcyclopropylamine; original trade name Parnate) is a monoamine oxidase inhibitor (MAOI); more specifically, tranylcypromaine acts as nonselective and irreversible inhibitor of the enzyme monoamine oxidase (MAO). It is used as an antidepressant and anxiolytic agent in the clinical treatment of mood and anxiety disorders, respectively. Tranylcypromine is a propylamine formed from the cyclization of amphetamine's side chain; therefore, it is classified as a substituted amphetamine.
CYCLOPROPANE (75-19-4)  
trimethylene
Cyclopropane is a cycloalkane molecule with the molecular formula C3H6, consisting of three carbon atoms linked to each other to form a ring, with each carbon atom bearing two hydrogen atoms resulting in D3h molecular symmetry. The small size of the ring creates substantial ring strain in the structure. Cyclopropane is an anaesthetic when inhaled.
2-Phenylcyclopropanamine (155-09-9)  
Tranylcypromine (contracted from trans-2-phenylcyclopropylamine; original trade name Parnate) is a monoamine oxidase inhibitor (MAOI); more specifically, tranylcypromaine acts as nonselective and irreversible inhibitor of the enzyme monoamine oxidase (MAO). It is used as an antidepressant and anxiolytic agent in the clinical treatment of mood and anxiety disorders, respectively. Tranylcypromine is a propylamine formed from the cyclization of amphetamine's side chain; therefore, it is classified as a substituted amphetamine.
Milnacipran (92623-85-3, 96847-55-1)  
Milnacipran (trade names Ixel, Savella, Dalcipran, Toledomin) is a serotonin–norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. It is not approved for the clinical treatment of major depressive disorder in the USA, but it is in other countries.
(1S,2R)-2-phenylcyclopropanamine (3721-28-6, 155-09-9)  
Tranylcypromine (contracted from trans-2-phenylcyclopropylamine; original trade name Parnate) is a monoamine oxidase inhibitor (MAOI); more specifically, tranylcypromaine acts as nonselective and irreversible inhibitor of the enzyme monoamine oxidase (MAO). It is used as an antidepressant and anxiolytic agent in the clinical treatment of mood and anxiety disorders, respectively. Tranylcypromine is a propylamine formed from the cyclization of amphetamine's side chain; therefore, it is classified as a substituted amphetamine.
PHORBOL (17673-25-5)  
Phorbol is a natural, plant-derived organic compound. It is a member of the tigliane family of diterpenes. Phorbol was first isolated in 1934 as the hydrolysis product of croton oil, which is derived from the seeds of the purging croton, Croton tiglium.
4-alpha-PHR (17673-25-5)  
Phorbol is a natural, plant-derived organic compound. It is a member of the tigliane family of diterpenes. Phorbol was first isolated in 1934 as the hydrolysis product of croton oil, which is derived from the seeds of the purging croton, Croton tiglium.
Enrofloxacin (93106-60-6)  
Enrofloxacin (ENR) is a fluoroquinolone antibiotic sold by the Bayer Corporation under the trade name Baytril. Enrofloxacin is currently approved by the FDA for the treatment of individual pets and domestic animals in the United States. In September 2005, the FDA withdrew approval of Baytril for use in water to treat flocks of poultry, as this practice was noted to promote the evolution of fluoroquinolone-resistant strains of the bacterium Campylobacter, a human pathogen.
Roflumilast (162401-32-3)  
Roflumilast (trade names Daxas, Daliresp) is a drug that acts as a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). It has anti-inflammatory effects and is used as an orally administered drug for the treatment of inflammatory conditions of the lungs such as chronic obstructive pulmonary disease (COPD). In June 2010, it was approved in the EU for severe COPD associated with chronic bronchitis.
Grepafloxacin (119914-60-2)  
Grepafloxacin hydrochloride (trade name Raxar, Glaxo Wellcome) was an oral broad-spectrum fluoroquinolone antibacterial agent used to treat bacterial infections. Grepafloxacin was withdrawn worldwide from markets in 1999, owing to its side effect of lengthening the QT interval on the electrocardiogram, leading to cardiac events and sudden death.
sparfloxacin (111542-93-9, 110871-86-8)  
Sparfloxacin (spar FLOX a sin), trade names Spacin in Bangladesh, Zagam and Zagam Respipac, is a fluoroquinolone antibiotic used in the treatment of bacterial infections. It has a controversial safety profile. Zagam is no longer available in the United States.
BICIFADINE (66504-75-4, 71195-57-8)  
Bicifadine (DOV-220,075) is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) discovered at American Cyanamid as an analgesic drug candidate, and licensed to DOV Pharmaceutical in 1998 after American Cyanamid was acquired by Wyeth. In January 2007, Dov licensed the rights to bicifadine to XTL Biopharmaceuticals after bicifadine failed in a Phase III clinical trial for chronic lower back pain. XTL ran a PhaseIIb clinical trial for pain caused by diabetic neuropathy, which failed in 2008; XTL terminated the agreement in 2010.
cirazoline (59939-16-1)  
LD-3098  ·  cirazoline monohydrochloride  ·  2-(2'-cyclopropylphenoxymethyl)imidazoline hydrochloride
Cirazoline is a full agonist at the α1A adrenergic receptor, a partial agonist at both the α1B and α1D adrenergic receptors, and a nonselective antagonist to the α2 adrenergic receptor. It is believed that this combination of properties could make cirazoline an effective vasoconstricting agent. Cirazoline has also been shown to decrease food intake in rats, purportedly through activation of α1 adrenoceptors in the paraventricular nucleus in the hypothalamus of the brain.
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