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D2 antagonists


Dopamine antagonists (15)
Drugs acting on the nervous system (15)
Psychoactive drugs (15)
Cyclic compounds (10)
Pharmaceuticals (10)
Aromatic compounds (9)
Antipsychotics (7)
Psychopharmacology (7)
Drugs acting on the cardiovascular system (5)
Fluoroarenes (5)
Six-membered rings (5)
Alpha blockers (4)
Antihistamines (4)
Antihypertensive agents (4)
D3 antagonists (4)
Drugs acting on the genito-urinary system (4)
Drugs for benign prostatic hyperplasia (4)
Typical antipsychotics (4)
Urologicals (4)
Alpha-1 blockers (3)
Alpha-2 blockers (3)
Chloroarenes (3)
Drugs acting on the gastrointestinal system and metabolism (3)
H1 receptor antagonists (3)
Piperidines (3)
Antiemetics (2)
Antiparkinsonian agents (2)
Atypical antipsychotics (2)
D4 antagonists (2)
Dopamine agonists (2)
Five-membered rings (2)
Motility stimulants (2)
Nervous system drug (2)
Piperazines (2)
Pyrrolidines (2)
5-HT3 antagonists (1)
Alcohols (1)
Alkaloids (1)
Alkenes (1)
Allyl compounds (1)
Amines (1)
Antiarrhythmic agents (1)
Antidepressants (1)
Aromatic ketones (1)
Bases (chemistry) (1)
D1 antagonists (1)
D1-receptor agonists (1)
D2-receptor agonists (1)
D3 receptor agonists (1)
Diphenylbutylpiperidines (1)
Ketones (1)
Mood stabilizers (1)
Potassium channel blockers (1)
Psychoanaleptics (1)
Psycholeptics (1)
Spiro compounds (1)
Ureas (1)


Sigma Aldrich (7)
AK Scientific (4)
TCI Chemicals (3)
Matrix Scientific (2)
Toronto Research Chemicals (2)
Accela (1)

Aripiprazole (129722-12-9)  
Aripiprazole, sold under the brand name Abilify among others, is an atypical antipsychotic. From April 2013 to March 2014, sales of Abilify amounted to almost $6.9 billion.. It is recommended by some doctors and used in the treatment of schizophrenia and bipolar disorder.
metoclopramide (364-62-5)  
Reglan  ·  Metoclopramide Hydrochloride  ·  Metaclopramide
Metoclopramide is a medication used mostly for stomach and esophageal problems. It is commonly used to treat and prevent nausea and vomiting, to help with emptying of the stomach in people with delayed stomach emptying, and to help with gastroesophageal reflux disease. It is also used to treat migraine headaches.
pimozide (2062-78-4)  
Orap  ·  Antalon  ·  Orap forte
Pimozide (sold under the brand name Orap) is an antipsychotic drug of the diphenylbutylpiperidine class. It was discovered at Janssen Pharmaceutica in 1963. It has a high potency compared to chlorpromazine (ratio 50-70:1).
trimethobenzamide (138-56-7)  
Tigan  ·  Ticon  ·  Tebamide
Trimethobenzamide (trade names Tebamide, Tigan) is an antiemetic used to prevent nausea and vomiting. It is often prescribed for patients with gastroenteritis, medication-induced nausea, and other illnesses. Trimethobenzamide is generally considered the most potent antiemetic that does not have effects on the serotonergic, dopaminergic, or histaminergic systems, so it has a lower likelihood of causing undesired side effects.
Itopride (122898-67-3)  
N-(p-(2-(dimethylamino)ethoxy)benzyl)veratramide hydrochloride
Itopride (INN) (brand name Ganaton) is a prokinetic benzamide derivative unlike metoclopramide or domperidone. These drugs inhibit dopamine and acetylcholine esterase enzyme and have a gastrokinetic effect. Itopride is indicated for the treatment of functional dyspepsia and other gastrointestinal conditions.
Aceprometazine (13461-01-3)  
aceprometazine maleate
Ketanserin (83846-83-7, 74050-98-9)  
R 41468  ·  R-41468  ·  R-41,468
Ketanserin (INN, USAN, BAN) (brand name Sufrexal; former developmental code name R41468) is a drug used clinically as an antihypertensive agent and in scientific research to study the serotonin system; specifically, the 5-HT2 receptor family. It was discovered at Janssen Pharmaceutica in 1980.
Pipamperone (1893-33-0)  
R 3345  ·  Dipiperon  ·  1'-(3-(4-fluorobenzoyl)propyl)-(1,4'-bipiperidine) -4'-carboxamide
Pipamperone (INN, USAN, BAN), also known as carpiperone and floropipamide or fluoropipamide, and as floropipamide hydrochloride (JAN), is a typical antipsychotic of the butyrophenone family used in the treatment of schizophrenia. It is or has been marketed under brand names including Dipiperon, Dipiperal, Piperonil, Piperonyl, and Propitan. Pipamperone was discovered at Janssen Pharmaceutica in 1961, and entered clinical trials in the United States in 1963.
Blonanserin (132810-10-7)  
Blonanserin, sold under the brand name Lonasen, is a relatively new atypical antipsychotic (approved by PMDA in January 2008) commercialized by Dainippon Sumitomo Pharma in Japan and Korea for the treatment of schizophrenia. Relative to many other antipsychotics, blonanserin has an improved tolerability profile, lacking side effects such as extrapyramidal symptoms, excessive sedation, or hypotension. As with many second-generation (atypical) antipsychotics it is significantly more efficacious in the treatment of the negative symptoms of schizophrenia compared to first-generation (typical) antipsychotics such as haloperidol.
spiperone (749-02-0)  
Spiroperidol  ·  Spiroperone
Spiperone (Spiroperidol; brand name: Spiropitan (JP)) is a typical antipsychotic and research chemical belonging to the butyrophenone chemical class. It is licensed for clinical use in Japan as a treatment for schizophrenia. Additionally, spiperone was identified by compound screening to be an activator of Ca2+ activated Cl− channels (CaCCs), thus a potential target for therapy of cystic fibrosis.
Eticlopride (84226-12-0)  
Eticlopride is a selective dopamine antagonist that acts on D2 dopamine receptor. It is primarily used in pharmacological research.
Ocaperidone (129029-23-8)  
Ocaperidone (also R 79598) is a benzisoxazole antipsychotic. It was initially developed by Janssen, later licensed to French laboratory Neuro3D and then acquired in 2007 by German company Evotec. Its testing was abandoned after phase II trials, as of 22 February 2010.
L-741,626 (81226-60-0)  
L-741,626 is a drug which acts as a potent and selective antagonist for the dopamine receptor D2. It has good selectivity over the related D3 and D4 subtypes and other receptors. L-741,626 is used for laboratory research into brain function and has proved particularly useful for distinguishing D2 mediated responses from those produced by the closely related D3 subtype, and for studying the roles of these subtypes in the action of cocaine and amphetamines in the brain.
D,L-Stepholidine (16562-14-4)  
(−)-Stepholidine is a protoberberine alkaloid found in the plant Stephania intermedia. Stepholidine activity includes dual D2 receptor antagonist and D1 receptor agonist, and has shown antipsychotic activity in animal studies.