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Dopamine agonists

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pramipexole (104632-26-0)  
Pramipexole (Mirapex, Mirapexin, Sifrol) is a dopamine agonist of the non-ergoline class indicated for treating Parkinson's disease (PD) and restless legs syndrome (RLS).
ropinirole (91374-21-9)  
Ropinirole (INN; trade names Requip, Repreve, Ronirol, Adartrel) is a dopamine agonist of the non-ergoline class of medications. It is manufactured by GlaxoSmithKline (GSK), Cipla, Dr. Reddy's Laboratories and Sun Pharmaceutical.
Aripiprazole (129722-12-9)  
Aripiprazole, sold under the brand name Abilify among others, is an atypical antipsychotic. From April 2013 to March 2014, sales of Abilify amounted to almost $6.9 billion.. It is recommended by some doctors and used in the treatment of schizophrenia and bipolar disorder.
Lysergide (50-37-3)  
LSD  ·  Lysergic Acid Diethylamide  ·  LSD 25
Lysergic acid diethylamide (LSD), also known as acid, is a psychedelic drug known for its psychological effects, which may include altered awareness of one's surroundings, perceptions, and feelings as well as sensations and images that seem real though they are not. It is used mainly as a recreational drug and for spiritual reasons. LSD is typically either swallowed or held under the tongue.
apomorphine (58-00-4, 314-19-2, 41372-20-7)  
Apomorphine Hydrochloride  ·  Apomorphin Teclapharm  ·  Hemihydrate Apomorphine Hydrochloride
Apomorphine (brand names Apokyn, Ixense, Spontane, Uprima) is a type of aporphine having activity as a non-selective dopamine agonist which activates both D2-like and, to a much lesser extent, D1-like receptors. It also acts as an antagonist of 5-HT2 and α-adrenergic receptors with high affinity. The compound is historically a morphine decomposition product by boiling with concentrated acid, hence the -morphine suffix.
modafinil (68693-11-8)  
Vigil  ·  Provigil  ·  Alertec
Modafinil, sold under the brand name Provigil among others, is a wakefulness-promoting drug used for treatment of disorders such as narcolepsy, shift work sleep disorder, idiopathic hypersomnia, and excessive daytime sleepiness associated with obstructive sleep apnea. It has also seen widespread off-label use as a purported cognitive enhancer. In the United States modafinil is classified as a schedule IV controlled substance and restricted in availability and usage, due to concerns about possible addiction potential.
bromocriptine (25614-03-3)  
Parlodel  ·  Bromocriptine Mesylate  ·  CB 154
Bromocriptine (originally marketed as Parlodel, subsequently under many names) is an ergoline derivative, is a dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease (PD), hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes.
Salvinorin A (83729-01-5)  
Salvinorin A is the main active psychotropic molecule in Salvia divinorum, a Mexican plant which has a long history of use as an entheogen by indigenous Mazatec shamans. Salvinorin A is considered a dissociative. It is structurally distinct from other naturally occurring hallucinogens (such as DMT, psilocybin, and mescaline) because it contains no nitrogen atoms; hence, it is not an alkaloid (and cannot be rendered as a salt) but a terpenoid.
fenoldopam (67227-57-0, 67227-56-9)  
Corlopam  ·  Fenoldopam Mesylate  ·  SKF 82526
Fenoldopam mesylate (Corlopam) is a drug and synthetic benzazepine derivative which acts as a selective D1 receptor partial agonist. Fenoldopam is used as an antihypertensive agent. It was approved by the Food and Drug Administration (FDA) in September 1997.
Captodiame (486-17-9)  
captodiamine  ·  2-((p-(Butylthio)-alpha-phenylbenzyl)thio)-N,N-dimethylethylamine
Captodiame (INN), also known as captodiamine, is an antihistamine sold under the trade names Covatine, Covatix, and Suvren which is used as a sedative and anxiolytic. It is a derivative of diphenhydramine. A 2004 study suggested captodiame may be helpful in preventing benzodiazepine withdrawal syndrome in people discontinuing benzodiazepine treatment.
piribedil (3605-01-4)  
ET 495  ·  Trivastal  ·  Piribedil Mesylate
Piribedil (trade names Pronoran, Trivastal Retard, Trastal, Trivastan, Clarium and others) is an antiparkinsonian agent and piperazine derivative which acts as a D2 and D3 receptor agonist. It also has α2-adrenergic antagonist properties.
Dexpramipexole (104632-28-2)  
Dexpramipexole (KNS-760704) is a drug that was investigated by Knopp Biosciences and Biogen Idec for the treatment of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. The drug failed to show efficacy in terms of function or survival in a Phase III study of patients with ALS. More recently, dexpramipexole was shown in a Phase 2 open-label trial to reduce eosinophil counts and eliminate the need for corticosteroid treatment in a subset of patients with steroid-responsive hypereosinophilic syndrome.
terguride (37686-84-3)  
transdihydrolisuride  ·  VUFB 6638  ·  dironyl maleate (1:1)
Terguride (INN), also known as trans-dihydrolisuride, is a serotonin receptor antagonist and dopamine receptor agonist of the ergoline family. It is approved for and used as a prolactin inhibitor in the treatment of hyperprolactinemia. Terguride is an oral, potent antagonist of 5-HT2B and 5-HT2A (serotonin) receptors.
Dopexamine (86197-47-9)  
Dopexamine is a synthetic analogue of dopamine that is administered intravenously in hospitals to reduce exacerbations of heart failure and to treat heart failure following cardiac surgery. It is not used often, as more established drugs like epinephrine, dopamine, dobutamine, norepinephrine, and levosimendan work as well. It works by stimulating beta-2 adrenergic receptors and peripheral dopamine receptor D1 and dopamine receptor D2.
Ibopamine (66195-31-1)  
SB 7505  ·  Escandine  ·  N-methyldopamine diisobutyrate
Ibopamine is a sympathomimetic drug, designed as a prodrug of epinine, used in ophthalmology. It induces mydriasis. It also has been investigated for use in the treatment of congestive heart failure.
metergoline (17692-51-2)  
Methergoline  ·  Metergoline Teofarma Brand  ·  Liserdol
Metergoline is a psychoactive drug of the ergoline chemical class which acts as a ligand for various serotonin and dopamine receptors.
Melevodopa (7101-51-1)  
Melevodopa (brand name Levomet) is a dopaminergic agent. It is the methyl ester of levodopa. It is used in tablet form as an effervescent prodrug with 250 times the water solubility of tablet levodopa.
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