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Dopamine antagonists


Drugs acting on the nervous system (80)
Psychoactive drugs (80)
Antipsychotics (63)
Psychopharmacology (63)
Cyclic compounds (60)
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Piperidines (23)
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Piperazines (16)
D2 antagonists (15)
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D4 antagonists (3)
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Dopamine agonists (3)
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Sigma Aldrich (29)
AK Scientific (16)
TCI Chemicals (13)
Matrix Scientific (10)
Toronto Research Chemicals (6)
Oakwood Chemical (4)
Accela (1)
Frontier Scientific (1)

Chlorpromazine (34468-21-8, 50-53-3)  
Thorazine  ·  Chlorpromazine Hydrochloride  ·  Largactil
Chlorpromazine (CPZ), marketed under the trade names Thorazine and Largactil among others, is an antipsychotic medication. It is primarily used to treat psychotic disorders such as schizophrenia. Other uses include the treatment of bipolar disorder, attention deficit hyperactivity disorder, nausea and vomiting, anxiety before surgery, and hiccups that do not improve following other measures.
Aripiprazole (129722-12-9)  
Aripiprazole, sold under the brand name Abilify among others, is an atypical antipsychotic. From April 2013 to March 2014, sales of Abilify amounted to almost $6.9 billion.. It is recommended by some doctors and used in the treatment of schizophrenia and bipolar disorder.
Risperidone (106266-06-2)  
Risperidone, sold under the trade name Risperdal among others, is an antipsychotic medication. It is mainly used to treat schizophrenia, bipolar disorder, and irritability in people with autism. It is taken either by mouth or by injection into a muscle.
Asenapine (65576-45-6)  
ORG 5222  ·  saphris  ·  asenapine maleate
Asenapine, sold under the trade names Saphris and Sycrest, is an atypical antipsychotic developed for the treatment of schizophrenia and acute mania associated with bipolar disorder. It was chemically derived via altering the chemical structure of the tetracyclic (atypical) antidepressant, mianserin.
metoclopramide (364-62-5)  
Reglan  ·  Metoclopramide Hydrochloride  ·  Metaclopramide
Metoclopramide is a medication used mostly for stomach and esophageal problems. It is commonly used to treat and prevent nausea and vomiting, to help with emptying of the stomach in people with delayed stomach emptying, and to help with gastroesophageal reflux disease. It is also used to treat migraine headaches.
thioridazine (50-52-2)  
Mellaril  ·  Thioridazine Hydrochloride  ·  Melleril
Thioridazine (Mellaril or Melleril) is a piperidine typical antipsychotic drug belonging to the phenothiazine drug group and was previously widely used in the treatment of schizophrenia and psychosis. The branded product was withdrawn worldwide in 2005 because it caused severe cardiac arrhythmias. However, generic versions are still available in the US.
perphenazine (58-39-9)  
Trilafon  ·  Perfenazine  ·  Chlorpiprazine
Perphenazine is a typical antipsychotic drug. Chemically, it is classified as a piperazinyl phenothiazine. Originally marketed in the US as Trilafon, it has been in clinical use for decades.
Paliperidone (144598-75-4)  
Paliperidone, sold under the trade name Invega among others, is a dopamine antagonist and 5-HT2A antagonist of the atypical antipsychotic class of medications. It is marketed by Janssen Pharmaceutica. Invega is an extended release formulation of paliperidone that uses the OROS extended release system to allow for once-daily dosing.
FLUPHENAZINE (69-23-8)  
Prolixin  ·  Fluphenazine Hydrochloride  ·  Flufenazin
Fluphenazine, sold under the brand names Prolixin among others, is an antipsychotic medication. It is used in the treatment of chronic psychoses such as schizophrenia, and appears to be about equal in effectiveness to low-potency antipsychotics like chlorpromazine. It is given by mouth, injection into a muscle, or just under the skin.
Lurasidone (367514-88-3, 367514-87-2)  
Lurasidone (trade name Latuda) is an atypical antipsychotic developed by Dainippon Sumitomo Pharma and marketed by Sunovion in the U.S. It has been an FDA approved treatment for schizophrenia since 2010 and for treating depressive episodes in adults with bipolar I disorder since 2013. It can be used alone or in combination with mood stabilizers such as lithium or valproate (e.g., Depakote).
haloperidol (61788-97-4, 52-86-8)  
Haloperidol, marketed under the trade name Haldol among others, is a typical antipsychotic medication. Haloperidol is used in the treatment of schizophrenia, tics in Tourette syndrome, mania in bipolar disorder, nausea and vomiting, delirium, agitation, acute psychosis, and hallucinations in alcohol withdrawal. It may be used by mouth, as an injection into a muscle, or intravenously.
Iloperidone (133454-47-4)  
Iloperidone, also known as Fanapt, Fanapta, and previously known as Zomaril, is an atypical antipsychotic for the treatment of schizophrenia.
fenfluramine (404-82-0, 5220-89-3, 458-24-2)  
Isomeride  ·  Pondimin  ·  Fenfluramine Hydrochloride
Fenfluramine and acid addition salts thereof, formerly sold under the brand name Pondimin among others, is an appetite suppressant which was used to treat obesity and is now no longer marketed. It was used both on its own and, in combination with phentermine, as part of the anti-obesity medication Fen-Phen.
Dexfenfluramine (3239-44-9)  
Dexfenfluramine, marketed as dexfenfluramine hydrochloride under the name Redux, is a serotonergic anorectic drug: it reduces appetite by increasing the amount of extracellular serotonin in the brain. It is the d-enantiomer of fenfluramine and is structurally similar to amphetamine, but lacks any psychologically stimulating effects. Dexfenfluramine was, for some years in the mid-1990s, approved by the United States Food and Drug Administration for the purposes of weight loss.
trifluoperazine (117-89-5)  
Stelazine  ·  Trifluoperazine Hydrochloride  ·  Trifluperazine
Trifluoperazine, sold under a number of brand names, is a typical antipsychotic primarily used to treat schizophrenia. It may also be used short term in those with generalized anxiety disorder but is less preferred to benzodiazepines. It is of the phenothiazine chemical class.
Levomepromazine (7104-38-3, 60-99-1)  
Methotrimeprazine  ·  Levopromazine  ·  Tizercine
mesoridazine (5588-33-0)  
Mesoridazine (Serentil) is a piperidine neuroleptic drug belonging to the class of drugs called phenothiazines, used in the treatment of schizophrenia. It is a metabolite of thioridazine. The drug's name is derived from the methylsulfoxy and piperidine functional groups in its chemical structure.
triflupromazine (146-54-3)  
Trifluopromazine  ·  Fluopromazine  ·  Bristol Myers Squibb Brand of Triflupromazine Hydrochloride
Triflupromazine (Vesprin) is an antipsychotic medication of the phenothiazine class. Among different effects of triflupromazine indication for use of this drug is severe emesis. Due to its potential side effects (triflupromazine has higher risk for side effects than many other antipsychotics) it is not gold standard in antiemetic therapy.
BUTAPERAZINE (653-03-2)  
Butaperazine (Repoise, Tyrylen) is a typical antipsychotic of the phenothiazine class.
pimozide (2062-78-4)  
Orap  ·  Antalon  ·  Orap forte
Pimozide (sold under the brand name Orap) is an antipsychotic drug of the diphenylbutylpiperidine class. It was discovered at Janssen Pharmaceutica in 1963. It has a high potency compared to chlorpromazine (ratio 50-70:1).
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