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Drugs acting on the respiratory system, Antitussives

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Respiratory system drug (40)
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codeine (52-28-8, 76-57-3)  
Codeine Phosphate  ·  Isocodeine  ·  Ardinex
Isocodeine is an opioid research chemical related to codeine. It is an epimer of codeine that can be prepared from it by a Mitsunobu reaction. Dozens of derivatives and analogs of isocodeine and the related compound isomorphine have been produced.
methadone (76-99-3)  
Dolophine  ·  Methadone Hydrochloride  ·  Amidone
Methadone, sold under the brand name Dolophine, among others, is an opioid used to treat pain and as maintenance therapy or to help with tapering in people with opioid dependence. Detoxification using methadone can either be done relatively rapidly in less than a month or gradually over as long as six months. While a single dose has a rapid effect, maximum effect can take five days of use.
Dextropropoxyphene (469-62-5, 2621-61-6, 2338-37-6)  
Propoxyphene  ·  Darvon  ·  Propoxyphene Hydrochloride
Dextropropoxyphene is an analgesic in the opioid category, patented in 1955 and manufactured by Eli Lilly and Company. It is an optical isomer of levopropoxyphene. It is intended to treat mild pain and also has antitussive (cough suppressant) and local anaesthetic effects.
Benzonatate (104-31-4)  
Tessalon
Benzonatate—marketed under the trade names Tessalon, Tessalon Perles, and Zonatuss—is a non-narcotic oral cough suppressant, or antitussive, with effects that last from six to eight hours. Since it is not an opioid, benzonatate is not as prone to abuse like some other cough medications such as codeine. Benzonatate was approved by the U.S.
Ethylmorphine (76-58-4)  
Dionine  ·  Ethylmorphine, (5alpha,6beta)-Isomer  ·  Ethylmorphine Hydrochloride, (5alpha,6alpha)-Isomer
Ethylmorphine (also known as codethyline, dionine, and ethyl morphine) is an opioid analgesic and antitussive.
OXTRIPHYLLINE (4499-40-5)  
Choledyl  ·  choline theophyllinate  ·  Brondecon
Choline theophyllinate (INN), also known as oxtriphylline, is a cough medicine derived from xanthine that acts as a bronchodilator to open up airways in the lung. Chemically, it is a salt of choline and theophylline. It classifies as an expectorant.
noscapine (6035-40-1, 128-62-1, 912-60-7)  
Narcotine  ·  Noscapine Hydrochloride  ·  Dreluso Brand of Noscapine Hydrochloride
Noscapine (also known as Narcotine, Nectodon, Nospen, Anarcotine and (archaic) Opiane) is a benzylisoquinoline alkaloid from plants of the poppy family, without painkilling properties. This agent is primarily used for its antitussive (cough-suppressing) effects.
Levopropoxyphene (2338-37-6)  
Levopropoxyphene is an antitussive. It is an optical isomer of dextropropoxyphene. The racemic mixture is called propoxyphene.
Erdosteine (84611-23-4, 105426-14-0)  
Erdosteine is a mucolytic. Specifically it is a thiol derivative developed for the treatment of chronic obstructive bronchitis, including acute infective exacerbation of chronic bronchitis. Erdosteine contains two blocked sulfhydryl groups which are released following first-pass metabolism.
carbetapentane (77-23-6, 1406-98-0)  
carbetapentane citrate  ·  pentoxyverine  ·  carbetapentane 1,5-napthalenedisulfonate (2:1)
Pentoxyverine (rINN) or carbetapentane is an antitussive (cough suppressant) commonly used for cough associated with illnesses like common cold. It is sold over-the-counter in the United States as Solotuss, or in combination with other medications, especially decongestants. One such product is Certuss, a combination of guaifenesin and pentoxyverine.
VERBENONE (80-57-9)  
verbenone, (1S)-isomer  ·  verbenone, (1R)-isomer  ·  verbenone, (+-)-isomer
Verbenone is a natural organic compound classified as a terpene that is found naturally in a variety of plants. The chemical has a pleasant characteristic odor. Besides being a natural constituent of plants, it and its analogs are insect pheromones.
Clofedanol (791-35-5)  
chlophedianol  ·  Baltix  ·  clofedanol hydrochloride
Clofedanol (INN) or chlophedianol (BAN) is a centrally acting cough suppressant used in the treatment of dry cough. Clofedanol has local anesthetic and antihistamine properties, and may have anticholinergic effects at high doses. It is marketed in Canada under the trade name Ulone, but is not available currently in the United States.
Levodropropizine (99291-25-5, 99291-24-4)  
Levodropropizine is a cough suppressant. It is the levo isomer of dropropizine. It acts as a peripheral antitussive, with no action in the central nervous system.
Oxeladin (468-61-1)  
oxeladin citrate  ·  Pectamol  ·  2-(2-diethylaminoethoxy)ethyl 2-ethyl-2-phenylbutyrate
Oxeladin is a cough suppressant. It is a highly potent and effective drug used to treat all types of cough of various etiologies. It is not related to opium or its derivatives, so treatment with oxeladin is free of risk of dependence or addiction.
PHOLCODINE (509-67-1)  
7,8-didehydro-4,5 alpha-epoxy-17-methyl-3-(2-morpholinoethoxymorphinan-6 alpha-ol)
Pholcodine is a drug which is an opioid cough suppressant (antitussive). It helps suppress unproductive coughs and also has a mild sedative effect, but has little or no analgesic effects. It is also known as morpholinylethylmorphine and homocodeine.
Levomethadone (125-58-6)  
Levomethadone (INN; L-Polamidon, L-Polamivet, Levadone, Levothyl), or levamethadone, is a synthetic opioid analgesic and antitussive which is marketed in Europe and is used for pain management and in opioid maintenance therapy. In addition to being used as a pharmaceutical drug itself, levomethadone, or R-(−)-methadone, is the active enantiomer of methadone, having approximately 50x the potency of the S-(+)-enantiomer as well as greater μ-opioid receptor selectivity. Accordingly, it is about twice as potent as methadone by weight and its effects are virtually identical in comparison.
dropropizine (117067-01-3, 99291-24-4, 17692-31-8)  
Levotuss  ·  levodropropizine  ·  dipropizine, (S)-isomer
Dropropizine (or dipropizine) is a cough suppressant. Commercialized in African countries, in Congo for instance.
Clobutinol (14860-49-2)  
KAT 250  ·  Silomat  ·  chlorodimenol
Clobutinol is a cough suppressant distributed by Boehringer-Ingelheim, Novartis's Hexal (Sandoz), Stada and possibly other companies.
Pipazethate (2167-85-3)  
Lenopect  ·  pipazethate monohydrochloride  ·  Theratuss
Pipazetate (INN) (brand names Dipect, Lenopect, Selvigon, Theratuss, Toraxan), or pipazethate (USAN), is a cough suppressant of the phenothiazine class.
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Drugs acting on the respiratory system
Antitussives
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