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Genito-urinary system drug

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Drugs acting on the genito-urinary system (167)
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bupropion (34841-39-9, 34911-55-2)  
Wellbutrin  ·  Bupropion Hydrochloride  ·  Quomen
Bupropion is a medication primarily used as an antidepressant and smoking cessation aid. It is marketed as Wellbutrin and Zyban among other trade names. It is one of the most frequently prescribed antidepressants in the United States and Canada, although in many countries this is an off-label use.
Aripiprazole (129722-12-9)  
Aripiprazole, sold under the brand name Abilify among others, is an atypical antipsychotic. From April 2013 to March 2014, sales of Abilify amounted to almost $6.9 billion.. It is recommended by some doctors and used in the treatment of schizophrenia and bipolar disorder.
megestrol (3562-63-8)  
Megestrol (INN, BAN) is a steroidal progestin of the 17α-hydroxyprogesterone group which was never marketed and is not currently used clinically. Its acylated derivative megestrol acetate is also a progestogen, which, in contrast to megestrol itself, has been extensively used as a pharmaceutical drug.
ethynodiol (1231-93-2)  
ethinodiol
Etynodiol, or ethynodiol, is a steroidal progestin of the 19-nortestosterone group which was never marketed. A diacylated derivative, etynodiol diacetate, is used as a hormonal contraceptive. While etynodiol is sometimes used as a synonym for etynodiol diacetate, it usually refers to etynodiol diacetate, not etynodiol.
alfuzosin (81403-80-7)  
Urion  ·  UroXatral  ·  alfuzosin hydrochloride
Alfuzosin (INN, provided as the hydrochloride salt) is a pharmaceutical drug of the α1 blocker class. As an antagonist of the α1 adrenergic receptor, it works by relaxing the muscles in the prostate and bladder neck, making it easier to urinate. It is thus used to treat benign prostatic hyperplasia (BPH).
dienestrol (35495-11-5, 84-17-3, 13029-44-2)  
Dienoestrol  ·  Ortho Dienestrol  ·  Dienestrol, (Z,E)-Isomer
Dienestrol (INN, USAN) (brand names Ortho Dienestrol, Dienoestrol, Dienoestrol Ortho, Sexadien, Denestrolin, Dienol, Dinovex, Follormon, Oestrodiene, Synestrol, numerous others), also known as dienoestrol (BAN), is a synthetic nonsteroidal estrogen of the stilbestrol group which is or was used to treat menopausal symptoms in the United States and Europe. It was introduced in the U.S. in 1947 by Schering as Synestrol and in France in 1948 as Cycladiene.
Estrodienol (35495-11-5)  
Dienestrol (INN, USAN) (brand names Ortho Dienestrol, Dienoestrol, Dienoestrol Ortho, Sexadien, Denestrolin, Dienol, Dinovex, Follormon, Oestrodiene, Synestrol, numerous others), also known as dienoestrol (BAN), is a synthetic nonsteroidal estrogen of the stilbestrol group which is or was used to treat menopausal symptoms in the United States and Europe. It was introduced in the U.S. in 1947 by Schering as Synestrol and in France in 1948 as Cycladiene.
Estrone sulfate (481-97-0, 7280-37-7)  
Evex  ·  oestrone sulphate  ·  sodium estrone sulfate
Estrone sulfate (E1S), or 17β-estrone 3-sulfate, is a natural, endogenous steroid and an estrogen ester and conjugate. It is a component of conjugated estrogens (Premarin) and esterified estrogens, and is also used as estropipate (piperazine estrone sulfate). E1S itself is biologically inactive, with less than 1% of the relative binding affinity of estradiol for the ERα and ERβ, but it can be converted by steroid sulfatase (also called estrogen sulfatase) into estrone, which is an estrogen.
acetohydroxamic acid (546-88-3)  
Lithostat  ·  Mission brand of acetohydroxamic acid  ·  Robert brand of acetohydroxamic acid
Acetohydroxamic acid (also known as AHA or Lithostat) is a drug that is a potent and irreversible inhibitor of bacterial and plant urease usually used for urinary tract infections. The molecule is similar to urea but is not hydrolyzable by the urease enzyme.
nylidrin (447-41-6)  
Arlidin  ·  Nylidrin Hydrochloride  ·  Dilatol
Buphenine (or nylidrin) is a β2 adrenoreceptor agonist that acts as a vasodilator.
hexestrol (84-16-2, 5635-50-7)  
Hexestrol, (R-(R*,R*))-Isomer  ·  Hexestrol, (R*,S*)-Isomer  ·  Dihydrodiethylstilbestrol
Hexestrol (INN) (brand names Synestrol, Synoestrol, Estrifar, Estronal, numerous others), also known as hexanestrol, hexoestrol, and dihydrodiethylstilbestrol, is a synthetic nonsteroidal estrogen of the stilbestrol group related to diethylstilbestrol which was used to treat estrogen deficiency. Oil solution of hexestrol is still manufactured in Russia under trade name Синэстрол.[1] Hexestrol has also been available and used in ester form, including as hexestrol diacetate, hexestrol dicaprylate, hexestrol diphosphate, and hexestrol dipropionate. Hexestrol has approximately 302% and 234% of the affinity of estradiol at the ERα and ERβ, respectively.
meso-Hexestrol (84-16-2)  
Hexestrol  ·  Hexestrol, (R-(R*,R*))-Isomer  ·  Hexestrol, (R*,S*)-Isomer
Estradiol mustard (22966-79-6)  
Estradiol mustard (developmental code name NSC-112259), also known as chlorphenacyl estradiol diester, as well as estradiol 3,17β-bis(4-(bis(2-chloroethyl)amino)phenyl)acetate, is a synthetic, steroidal estrogen and alkylating antineoplastic agent and a chlorphenacyl nitrogen mustard-coupled estrogen ester that was never marketed. It is selectively distributed into estrogen receptor (ER)-positive tissues such as ER-expressing tumors like those seen in breast and prostate cancers. For this reason, estradiol mustard and other cytostatic-linked estrogens like estramustine phosphate have reduced toxicity relative to non-linked nitrogen mustard alkylating antineoplastic agents.
Butoconazole (64872-76-0, 64872-77-1)  
Butoconazole (trade names Gynazole-1, Mycelex-3) is an imidazole antifungal used in gynecology. It is administered as a vaginal cream.
QUINESTROL (152-43-2)  
Estrovis  ·  Ethinyl Estradiol 3 Cyclopentyl Ether  ·  Ethinyl Estradiol 3-Cyclopentyl Ether
Quinestrol (INN, USAN, BAN) (brand names Agalacto-Quilea, Basaquines, Eston, Estrovis, Estrovister, Plestrovis, Qui-Lea), also known as ethinylestradiol 3-cyclopentyl ether (EE2CPE), is a synthetic, steroidal estrogen which is used in menopausal hormone therapy and occasionally to treat breast cancer and prostate cancer. It is a prodrug of ethinylestradiol (with cyclopentanol also being formed) with no intrinsic estrogenic activity of its own, and has a very long terminal half-life of more than 120 hours due to enhanced lipophilicity. Because of its much longer terminal half-life, quinestrol is two to three times as potent as ethinylestradiol.
METHALLENESTRIL (517-18-0)  
Vallestril  ·  methallenestril, (+)-isomer  ·  methallenestril, (+-)-isomer
Methallenestril (INN) (brand names Cur-men, Ercostrol, Geklimon, Novestrine, Vallestril), also known as methallenoestril (BAN) and as methallenestrol, as well as Horeau's acid, is a synthetic nonsteroidal estrogen and a derivative of allenolic acid and allenestrol (specifically, a methyl ether of it) that was formerly used to treat menstrual issues but is now no longer marketed. It is a seco-analogue of bisdehydrodoisynolic acid, and although methallenestril is potently estrogenic in rats, in humans it is only weakly so in comparison. Vallestril was a brand of methallenestril issued by G.
16alpha-Hydroxyestrone (566-76-7)  
16α-Hydroxyestrone (16α-OH-E1), or hydroxyestrone, also known as estra-1,3,5(10)-trien-3,16α-diol-17-one, is an endogenous steroidal estrogen and a major metabolite of estrone, as well as an intermediate in the biosynthesis of estriol. It is a potent estrogen similarly to estrone, and it has been suggested that the ratio of 16α-hydroxyestrone to 2-hydroxyestrone, the latter being much less estrogenic in comparison and even antiestrogenic in the presence of more potent estrogens like estradiol, may be involved in the pathophysiology of breast cancer. Conversely, 16α-hydroxyestrone may help to protect against osteoporosis.
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