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Kappa agonists, Alkaloid, www.sigmaaldrich.com

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Alkaloids (1)
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Matrine (519-02-8)  
Matrine is an alkaloid found in plants from the Sophora genus. It has a variety of pharmacological effects, including anti-cancer effects, as well as κ-opioid and μ-opioid receptor agonism. Matrine possesses strong antitumor activities in vitro and in vivo.

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Metofoline (14415-95-3, 180003-15-0, 2154-02-1)  
Metofoline ([[International nonproprietary name|INN), also known as methofoline (USAN), is an opioid analgesic drug discovered in the 1950s by a team of Swiss researchers at Hoffmann-La Roche. Methopholine is an isoquinoline derivative which is not structurally related to most other opioids. However, its structural similarity to papaverine is notable.
ISOQUINOLINE (119-65-3)  
isoquinoline hydrochloride  ·  isoquinoline conjugate acid  ·  isoquinoline hydrobromide
Isoquinoline is a heterocyclic aromatic organic compound. It is a structural isomer of quinoline. Isoquinoline and quinoline are benzopyridines, which are composed of a benzene ring fused to a pyridine ring.
1,2,3,4-Tetrahydroisoquinoline (91-21-4, 14099-81-1)  
tetrahydroisoquinoline  ·  1,2,3,4-tetrahydro-2-azanaphthalene  ·  HCl of 1,2,3,4-tetrahydroisoquinoline
Tetrahydroisoquinoline (TIQ) is an organic compound with the chemical formula C9H11N. Classified as a secondary amine, it is derived from isoquinoline by hydrogenation. It is a colorless viscous liquid that is miscible with most organic solvents.
ALPHA-PHELLANDRENE (4221-98-1, 1329-99-3, 99-83-2, 34448-33-4)  
alpha phellandrene, (S+)-isomer  ·  alpha phellandrene, (R)-isomer  ·  5-isopropyl-2-methyl-1,3-cyclohexadiene
Phellandrene is the name for a pair of organic compounds that have a similar molecular structure and similar chemical properties. α-Phellandrene and β-phellandrene are cyclic monoterpenes and are double-bond isomers. In α-phellandrene, both double bonds are endocyclic and in β-phellandrene, one of them is exocyclic.
15532-75-9 (15532-75-9)  
TFMPP  ·  1-(m-trifluoromethylphenyl)piperazine  ·  1-(3-trifluoromethylphenyl)piperazine
3-Trifluoromethylphenylpiperazine (TFMPP) is a recreational drug of the piperazine chemical class. Usually in combination with its analogue benzylpiperazine (BZP), it is sold as an alternative to the illicit drug MDMA ("Ecstasy") under the name "Legal X".
5-Nitroisoquinoline (607-32-9)  
5-nitroquinoline
1-METHYLISOQUINOLINE (1721-93-3, 58853-80-8)  
1-methylisoquinoline hydroiodide
EXIFONE (52479-85-3, 72841-23-7)  
hexahydro-2,3,4,3',4',5'-benzophenone  ·  Adlone
Compound VII (98033-68-2)  
WIN 53338  ·  WIN-53338  ·  WIN53338
3-(2-Aminopropyl)indole (299-26-3, 304-54-1)  
α-Methyltryptamine (abbreviated as αMT, AMT) is a psychedelic, stimulant, and entactogen drug of the tryptamine class. It was originally developed as an antidepressant by workers at Upjohn in the 1960s, and was used briefly as an antidepressant in Russia under the trade name Indopan before being discontinued.
2H-Chromene (254-04-6)  
Benzopyran is an polycyclic organic compound that results from the fusion of a benzene ring to a heterocyclic pyran ring. According to current IUPAC nomenclature, the name chromene used in previous recommendations is retained; however, systematic ‘benzo’ names, for example 2H-1-benzopyran, are preferred IUPAC names for chromene, isochromene, chromane, isochromane, and their chalcogen analogues. There are two isomers of benzopyran that vary by the orientation of the fusion of the two rings compared to the oxygen, resulting in 1-benzopyran (chromene) and 2-benzopyran (isochromene)—the number denotes where the oxygen atom is located by standard naphthalene-like nomenclature.
N-(pyridin-4-yl)benzamide (5221-44-3)  
N-(4-pyridyl)benzamide
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