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Kappa agonists, Analgesic, Allyl compounds

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Alkenes (1)
Analgesics (1)
Cyclic compounds (1)
Cycloalkenes (1)
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Nalorphine (62-67-9)  
Allylnormorphine  ·  Nalorphine Hydrochloride  ·  Lethidrone
Nalorphine (INN) (brand names Lethidrone, Nalline), also known as N-allylnormorphine, is a mixed opioid agonist–antagonist with opioid antagonist and analgesic properties. It was introduced in 1954 and was used as an antidote to reverse opioid overdose and in a challenge test to determine opioid dependence. It acts at two opioid receptors — the μ-opioid receptor (MOR) where it has antagonistic effects, and at the κ-opioid receptor (KOR) (Ki = 1.6 nM; EC50 = 483 nM; Emax = 95%) where it exerts high-efficacy partial agonist/near-full agonist characteristics.

Related Results:
Allyl ionone (79-78-7)  
allyl alpha-ionone
TENOCYCLIDINE (21500-98-1, 1867-65-8)  
Tenocyclidine (TCP) was discovered by a team at Parke Davis in the late 1950s. It is a dissociative anesthetic drug with psychostimulant and hallucinogenic effects. It is similar in effects to phencyclidine (PCP) but is considerably more potent.
2-Hydroxybenzophenone (117-99-7)  
ortho-hydroxybenzophenone
Compound VII (98033-68-2)  
WIN 53338  ·  WIN-53338  ·  WIN53338
Related searches
Kappa agonists
Analgesic
Allyl compounds
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