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Kappa agonists, Cyclic compounds, Fluoroarenes, Opioids

Categories

Analgesics (2)
Aromatic compounds (2)
Benzodiazepines (2)
Drugs acting on the nervous system (2)
Opioid receptor ligands (2)
Psychoactive drugs (2)
Analgesic (1)
Dissociative drugs (1)
Five-membered rings (1)
Thiophenes (1)

Tifluadom (83386-35-0)  
KC 5103  ·  KC 5911  ·  KC-5911
Tifluadom is a benzodiazepine derivative with an unusual activity profile. Unlike most benzodiazepines, tifluadom has no activity at the GABAA receptor, but instead is a selective agonist for the κ-opioid receptor. In accordance, it has potent analgesic and diuretic effects in animals, and also has sedative effects and stimulates appetite.
Lufuradom (85118-42-9, 94006-14-1)  
Lufuradom (INN) is a drug and benzodiazepine derivative which, unlike other benzodiazepines, is described as an analgesic. Similarly to its analogue tifluadom, it was never marketed.
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Kappa agonists
Cyclic compounds
Fluoroarenes
Opioids