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Kappa agonists, Opioid receptor ligands, Drugs acting on the nervous system, Analgesic, Alkaloid, Morphine

Categories

Analgesics (2)
Ethers (2)
Euphoriants (2)
Mu-opioid agonists (2)
Natural opium alkaloids (2)
Opiates (2)
Opioids (2)
Opium (2)
Psychoactive drugs (2)
Pharmaceuticals (1)

WIN VI (98034-30-1)  
Win 52035  ·  WIN 52035-2  ·  5-(5-(4-(4,5-dihydro-2-oxazolyl)phenoxy)pentyl)-3-methylisoxazole
Loperamide hydrochloride (34552-83-5)  
Loperamide  ·  Imodium  ·  Loperamide Monohydrochloride
Loperamide, sold under the brand name Imodium among others, is a medication used to decrease the frequency of diarrhea. It is often used for this purpose in gastroenteritis, inflammatory bowel disease, and short bowel syndrome. It is not recommended for those with blood in the stool.
CYTISINE (485-35-8)  
Tsitizin  ·  cytisine hydrochloride, hydrate  ·  cytisine hydrochloride
Cytisine, also known as baptitoxine and sophorine, is an alkaloid that occurs naturally in several plant genera, such as Laburnum and Cytisus of the family Fabaceae. It has been used medically to help with smoking cessation. Its molecular structure has some similarity to that of nicotine and it has similar pharmacological effects.
Nefopam hydrochloride (69319-31-9, 23327-57-3)  
Ajan  ·  Nefopam  ·  3M Brand of Nefopam Hydrochloride
1-(4-Chlorobenzhydryl)piperazine (303-26-4)  
norchlorcyclizine  ·  norchlorcyclizine hydrochloride  ·  N-(p-chlorobenzhydryl)piperazine
Buspirone hydrochloride (33386-08-2)  
Buspirone  ·  Buspar  ·  Neurosine
Buspirone, sold under the brand name Buspar, is an anxiolytic drug that is primarily used to treat generalized anxiety disorder (GAD). It is also commonly used to augment antidepressants in the treatment of major depressive disorder. Unlike most anxiolytics, the pharmacology of buspirone is not related to that of benzodiazepines, barbiturates, or carbamates (it is not a GABA receptor agonist), and so buspirone does not carry the risk of physical dependence and withdrawal symptoms for which those drug classes are known.
Etifoxine (21715-46-8)  
Etifoxine (INN, also known as etafenoxine; trade name Stresam) is an anxiolytic and anticonvulsant drug developed by Hoechst in the 1960s. It is sold in approximately 40 countries for anxiety disorders, without the sedation and ataxia associated with benzodiazepine drugs. It has similar anxiolytic effects to benzodiazepine drugs, but is structurally distinct and does not bind to the benzodiazepine receptor.
Etifoxine hydrochloride (21715-46-8, 56776-32-0)  
etifoxin  ·  etafenoxine  ·  Stresam
1-PHENYLPIPERAZINE (92-54-6)  
phenylpiperazine  ·  phenylpiperazine monohydrochloride  ·  phenylpiperazine dihydrobromide
1-Phenylpiperazine is a simple chemical compound featuring a phenyl group bound to a piperazine ring. The suffix ‘-piprazole’ is sometimes used in the names of drugs to indicate they belong to this class. A number of phenylpiperazine derivatives are drugs, including: Pharmaceuticals: Research chemicals: Designer drugs:
nefopam (13669-70-0)  
Ajan  ·  3M Brand of Nefopam Hydrochloride  ·  Acupan
Nefopam, sold under the brand names Acupan among others, is a painkilling medication. It is primarily used to treat moderate, acute or chronic pain. It is believed to work in the brain and spinal cord to relieve pain.
Levomethorphan (125-70-2)  
Dextromethorphan  ·  Dextromethorphan Hydrobromide  ·  Delsym
pentazocine (7488-49-5, 359-83-1, 21820-34-8, 55643-30-6)  
Talwin  ·  Pentazocine Hydrochloride  ·  Pentazocine Lactate
Pentazocine, sold under the brand name Talwin among others, is a painkiller used to treat moderate to severe pain. It is believed to work by activating (agonizing) κ-opioid receptors (KOR) and blocking (antagonizing) μ-opioid receptors (MOR). As such it is called an opioid as it delivers its effects on pain by interacting with the opioid receptors.
Talwin (359-83-1, 55643-30-6)  
Pentazocine  ·  Pentazocine Hydrochloride  ·  Pentazocine Lactate
Pentazocine lactate (17146-95-1)  
Pentazocine  ·  Talwin  ·  Pentazocine Hydrochloride
TENOCYCLIDINE (21500-98-1, 1867-65-8)  
Tenocyclidine (TCP) was discovered by a team at Parke Davis in the late 1950s. It is a dissociative anesthetic drug with psychostimulant and hallucinogenic effects. It is similar in effects to phencyclidine (PCP) but is considerably more potent.
Ro 48-8071 (161582-11-2)  
Ro 48-8071hydrochloride  ·  (4'-(6-allylmethylaminohexyloxy)-2'-fluorophenyl)-4-(4-bromophenyl)methanone fumarate  ·  Ro-48-8071
loperamide (53179-11-6)  
Imodium  ·  Loperamide Hydrochloride  ·  Loperamide Monohydrochloride
Loperamide, sold under the brand name Imodium among others, is a medication used to decrease the frequency of diarrhea. It is often used for this purpose in gastroenteritis, inflammatory bowel disease, and short bowel syndrome. It is not recommended for those with blood in the stool.
Pravadoline (92623-83-1)  
Pravadoline (WIN 48,098) is an antiinflammatory and analgesic drug with an IC50 of 4.9 µM and a Ki of 2511 nM at CB1, related in structure to nonsteroidal anti-inflammtory drugs (NSAIDs) such as indometacin. It was developed in the 1980s as a new antiinflammatory and prostaglandin synthesis inhibitor, acting through inhibition of the enzyme cyclooxygenase (COX). However, pravadoline was found to exhibit unexpectedly strong analgesic effects, which appeared at doses ten times smaller than the effective anti-inflammatory dose and so could not be explained by its action as a COX inhibitor.
Related searches
Kappa agonists
Opioid receptor ligands
Drugs acting on the nervous system
Analgesic
Alkaloid
Morphine
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