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Kappa agonists, Opioid receptor ligands, Drugs acting on the nervous system, Analgesic, Alkaloid, Opioids, Analgesics

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Psychoactive drugs (5)
Alkaloids (3)
Cyclic compounds (3)
Heterocyclic compounds (3)
Heterocyclic compounds (4 or more rings) (3)
Polycyclic organic compounds (3)
Ethers (2)
Euphoriants (2)
Morphine (2)
Mu-opioid agonists (2)
Natural opium alkaloids (2)
Opiates (2)
Opium (2)
Pharmaceuticals (1)

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Sigma Aldrich (1)
TCI Chemicals (1)

Nicomorphine (639-48-5)  
Vilan  ·  morphine dinicotinate  ·  bis(nicotinyl)morphine
Nicomorphine (Vilan, Subellan, Gevilan, MorZet) is the 3,6-dinicotinate ester of morphine. It is a strong opioid agonist analgesic two to three times as potent as morphine with a side effect profile similar to that of dihydromorphine, morphine, and diamorphine. Nicomorphine was patented as Vilan by Lannacher Heilmittel G.m.b.H.
Subutex (53152-21-9)  
Buprenorphine  ·  Buprenex  ·  Buprenorphine Hydrochloride
buprenorphine (52485-79-7)  
Buprenex  ·  Buprenorphine Hydrochloride  ·  Subutex
Buprenorphine, sold under the brand name Subutex, among others, is an opioid used to treat opioid addiction, acute pain, and chronic pain. It can be used under the tongue, by injection, as a skin patch, or as an implant. When used for opioid addiction it is recommended that a health care provider observe the person while they take the medication.
Loperamide hydrochloride (34552-83-5)  
Loperamide  ·  Imodium  ·  Loperamide Monohydrochloride
Loperamide, sold under the brand name Imodium among others, is a medication used to decrease the frequency of diarrhea. It is often used for this purpose in gastroenteritis, inflammatory bowel disease, and short bowel syndrome. It is not recommended for those with blood in the stool.
Diprenorphine (14357-78-9)  
Revivon  ·  Diprenorphine Hydrochloride
Diprenorphine (brand name Revivon; former developmental code name M5050), also known as diprenorfin, is a non-selective, high-affinity, weak partial agonist of the μ- (MOR), κ- (KOR), and δ-opioid receptor (DOR) (with equal affinity) that is employed in veterinary medicine as an opioid antagonist. It is used to reverse the effects of super-potent opioid analgesics such as etorphine and carfentanil that are used for tranquilizing large animals. The drug is not approved for use in humans.
CLONIDINE HYDROCHLORIDE (4205-91-8)  
Clonidine  ·  Catapres  ·  Dixarit
Clonidine (trade names Catapres, Kapvay, Nexiclon, Clophelin, and others) is a medication used to treat high blood pressure, attention deficit hyperactivity disorder, anxiety disorders, tic disorders, withdrawal (from either alcohol, opioids, or smoking), migraine, menopausal flushing, diarrhea, and certain pain conditions. It is classified as a centrally acting α2 adrenergic agonist and imidazoline receptor agonist that has been in clinical use since 1966.
clonidine (4205-90-7)  
Catapres  ·  Clonidine Hydrochloride  ·  Dixarit
Clonidine (trade names Catapres, Kapvay, Nexiclon, Clophelin, and others) is a medication used to treat high blood pressure, attention deficit hyperactivity disorder, anxiety disorders, tic disorders, withdrawal (from either alcohol, opioids, or smoking), migraine, menopausal flushing, diarrhea, and certain pain conditions. It is classified as a centrally acting α2 adrenergic agonist and imidazoline receptor agonist that has been in clinical use since 1966.
gabapentin (60142-96-3)  
Neurontin  ·  PMS-Gabapentin  ·  Novo-Gabapentin
Gabapentin, sold under the brand names Neurontin among others, is a medication used to treat epilepsy, neuropathic pain, hot flashes, and restless legs syndrome. In epilepsy, it may be used for those with partial seizures. It is recommended as one of a number of first line medications for the treatment of neuropathic pain in diabetic neuropathy, postherpetic neuralgia, and central neuropathic pain.
Naltrexone hydrochloride (16676-29-2)  
Naltrexone  ·  ReVia  ·  Trexan
naltrexone (16590-41-3, 16676-29-2)  
ReVia  ·  Trexan  ·  Naltrexone Hydrochloride
Naltrexone, sold under the brand names Revia and Vivitrol among others, is a medication primarily used to manage alcohol dependence and opioid dependence. In opioid dependence, it should not be started until people are detoxified. It is taken by mouth or by injection into a muscle.
CYCLAZOCINE (3572-80-3, 63903-61-7, 7346-09-0)  
Cyclazocine is a mixed opioid agonist/antagonist related to dezocine, pentazocine and phenazocine. This family of opioid drugs is called the benzomorphans or benzazocines. It is a KOR agonist and MOR partial agonist, and also has high affinity for the DOR.
tizanidine (51322-75-9)  
Tizanidine (trade names Zanaflex (Acorda Therapeutics), Sirdalud (Novartis), Relentus (Beximco Pharma) Is a centrally acting α2 adrenergic agonist used as a muscle relaxant. It is used to treat the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, ALS, spastic diplegia, back pain, or certain other injuries to the spine or central nervous system. It is also prescribed off-label for migraine headaches, as a sleep aid, and as an anticonvulsant.
1022-13-5 (1022-13-5)  
2-MACB  ·  2-methylamino-5-chlorobenzophenone  ·  2-(N-methylamino)-5-chlorobenzophenone
Heroin hydrochloride (1502-95-0)  
Heroin  ·  Diamorphine  ·  Diacetylmorphine
Diacetylmorphine (561-27-3)  
Heroin  ·  Diamorphine  ·  Heroin Hydrochloride
Heroin, also known as diamorphine among other names, is an opioid most commonly used as a recreational drug for its euphoric effects. Medically it is used in several countries to relieve pain or in opioid replacement therapy. Heroin is typically injected, usually into a vein; however, it can also be smoked, snorted or inhaled.
Buspirone hydrochloride (33386-08-2)  
Buspirone  ·  Buspar  ·  Neurosine
Buspirone, sold under the brand name Buspar, is an anxiolytic drug that is primarily used to treat generalized anxiety disorder (GAD). It is also commonly used to augment antidepressants in the treatment of major depressive disorder. Unlike most anxiolytics, the pharmacology of buspirone is not related to that of benzodiazepines, barbiturates, or carbamates (it is not a GABA receptor agonist), and so buspirone does not carry the risk of physical dependence and withdrawal symptoms for which those drug classes are known.
15532-75-9 (15532-75-9)  
TFMPP  ·  1-(m-trifluoromethylphenyl)piperazine  ·  1-(3-trifluoromethylphenyl)piperazine
3-Trifluoromethylphenylpiperazine (TFMPP) is a recreational drug of the piperazine chemical class. Usually in combination with its analogue benzylpiperazine (BZP), it is sold as an alternative to the illicit drug MDMA ("Ecstasy") under the name "Legal X".
tramadol hydrochloride (36282-47-0, 53611-16-8)  
Tramadol  ·  Ultram  ·  Tramal
Tramadol, sold under the brand name Ultram among others, is an opioid pain medication used to treat moderate to moderately severe pain. When taken by mouth in an immediate-release formulation, the onset of pain relief usually occurs within an hour. It is often combined with paracetamol (acetaminophen) as this is known to improve the efficacy of tramadol in relieving pain.
Lofexidine (31036-80-3)  
Lofexidine (sold under the brand names: BritLofex and Kai Er Ding) is an α2A adrenergic receptor agonist, historically used as an antihypertensive, but more commonly used to alleviate the physical symptoms of heroin and other types of opioid withdrawal.
memantine (19982-08-2)  
Namenda  ·  D 145  ·  D145
Memantine is used to treat moderate to severe Alzheimer's disease. It acts on the glutamatergic system by blocking NMDA receptors. It was first synthesized by Eli Lilly and Company in 1968 as a potential agent to treat diabetes; the NMDA activity was discovered in the 1980s.
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Kappa agonists
Opioid receptor ligands
Drugs acting on the nervous system
Analgesic
Alkaloid
Opioids
Analgesics
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