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Kappa agonists, Opioid receptor ligands, Drugs acting on the nervous system, Analgesic, Mu-opioid agonists, Ketones

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Amines (1)
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norketamine (35211-10-0)  
Norketamine, or N-desmethylketamine, is the major active metabolite of ketamine, which is formed mainly by CYP3A4. Similarly to ketamine, norketamine acts as a noncompetitive NMDA receptor antagonist (Ki = 1.7 µM and 13 µM for (S)-(+)-norketamine and (R)-(–)-norketamine, respectively), but is about 3–5 times less potent as an anesthetic in comparison. Also, similarly again to ketamine, norketamine binds to the μ- and κ-opioid receptors.
Related searches
Kappa agonists
Opioid receptor ligands
Drugs acting on the nervous system
Analgesic
Mu-opioid agonists
Ketones