Kappa agonists, Opioid receptor ligands, Drugs acting on the nervous system, Ethers, Psychoactive drugs, Semisynthetic opioids
Cyclic compounds (2)
M99 · Ethorphine
Nubain · Nalbuphine Hydrochloride · EN-2234A
Nalbuphine is a semi-synthetic opioid agonist-antagonist used commercially as an analgesic under a variety of trade names, including Nubain and Manfine.
Revivon · Diprenorphine Hydrochloride
Diprenorphine (brand name Revivon; former developmental code name M5050), also known as diprenorfin, is a non-selective, high-affinity, weak partial agonist of the μ- (MOR), κ- (KOR), and δ-opioid receptor (DOR) (with equal affinity) that is employed in veterinary medicine as an opioid antagonist. It is used to reverse the effects of super-potent opioid analgesics such as etorphine and carfentanil that are used for tranquilizing large animals. The drug is not approved for use in humans.
Cyprenorphine (M-285) is an opioid drug. It is related to more well-known opioids such as buprenorphine, which is used as an analgesic and for the treatment of opioid addiction, and diprenorphine, which is used as an antidote to reverse the effects of other opioids. Cyprenorphine has mixed agonist–antagonist effects at opioid receptors, like those of buprenorphine.