Kappa agonists, Opioid receptor ligands, Drugs acting on the nervous system, Psychedelic drugs, Pyrrolidines
Cyclic compounds (2)
Spiro compounds (2)
Enadoline is a drug which acts as a highly selective κ-opioid agonist. In human studies, it produced visual distortions and feelings of dissociation, reminiscent of the effects of salvinorin A. It was studied as a potential analgesic, but abandoned because of the dose-limiting effects of dysphoria, which could be expected from a κ-opioid agonist.