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Kappa agonists, Opioid receptor ligands, Drugs acting on the nervous system, Thiophenes, Opioids

Categories

Analgesics (1)
Aromatic compounds (1)
Benzodiazepines (1)
Cyclic compounds (1)
Dissociative drugs (1)
Five-membered rings (1)
Fluoroarenes (1)
Psychoactive drugs (1)

Tifluadom (83386-35-0)  
KC 5103  ·  KC 5911  ·  KC-5911
Tifluadom is a benzodiazepine derivative with an unusual activity profile. Unlike most benzodiazepines, tifluadom has no activity at the GABAA receptor, but instead is a selective agonist for the κ-opioid receptor. In accordance, it has potent analgesic and diuretic effects in animals, and also has sedative effects and stimulates appetite.

Related Results:
15532-75-9 (15532-75-9)  
TFMPP  ·  1-(m-trifluoromethylphenyl)piperazine  ·  1-(3-trifluoromethylphenyl)piperazine
3-Trifluoromethylphenylpiperazine (TFMPP) is a recreational drug of the piperazine chemical class. Usually in combination with its analogue benzylpiperazine (BZP), it is sold as an alternative to the illicit drug MDMA ("Ecstasy") under the name "Legal X".
TENOCYCLIDINE (21500-98-1, 1867-65-8)  
Tenocyclidine (TCP) was discovered by a team at Parke Davis in the late 1950s. It is a dissociative anesthetic drug with psychostimulant and hallucinogenic effects. It is similar in effects to phencyclidine (PCP) but is considerably more potent.
WIN VI (98034-30-1)  
Win 52035  ·  WIN 52035-2  ·  5-(5-(4-(4,5-dihydro-2-oxazolyl)phenoxy)pentyl)-3-methylisoxazole
1-PHENYLPIPERAZINE (92-54-6)  
phenylpiperazine  ·  phenylpiperazine monohydrochloride  ·  phenylpiperazine dihydrobromide
1-Phenylpiperazine is a simple chemical compound featuring a phenyl group bound to a piperazine ring. The suffix ‘-piprazole’ is sometimes used in the names of drugs to indicate they belong to this class. A number of phenylpiperazine derivatives are drugs, including: Pharmaceuticals: Research chemicals: Designer drugs:
Compound VII (98033-68-2)  
WIN 53338  ·  WIN-53338  ·  WIN53338
1-(4-Chlorobenzhydryl)piperazine (303-26-4)  
norchlorcyclizine  ·  norchlorcyclizine hydrochloride  ·  N-(p-chlorobenzhydryl)piperazine
MMDA (13674-05-0)  
MMDA (3-methoxy-4,5-methylenedioxyamphetamine; 5-methoxy-MDA) is a psychedelic and entactogen drug of the amphetamine class. It is an analogue of lophophine, MDA, and MDMA. MMDA was described by Alexander Shulgin in his book PiHKAL.
1-Phenylpiperazine dihydrochloride (4004-95-9)  
phenylpiperazine  ·  1-phenylpiperazine  ·  phenylpiperazine monohydrochloride
N-Methylphenethylamine (589-08-2)  
N-methylphenethylamine hydrochloride  ·  N-methylphenylethylamine  ·  N-methyl-beta-phenethylamine
N-Methylphenethylamine (NMPEA) is a naturally occurring trace amine neuromodulator in humans that is derived from the trace amine, phenethylamine (PEA). It has been detected in human urine (<1 μg over 24 hours) and is produced by phenylethanolamine N-methyltransferase with phenethylamine as a substrate. PEA and NMPEA are both alkaloids that are found in a number of different plant species as well.
1-Phenylpiperazine hydrochloride (2210-93-7)  
phenylpiperazine  ·  1-phenylpiperazine  ·  phenylpiperazine monohydrochloride
EXIFONE (52479-85-3, 72841-23-7)  
hexahydro-2,3,4,3',4',5'-benzophenone  ·  Adlone
QUINUCLIDINE (100-76-5)  
Quinuclidine is an organic compound and a bicyclic amine and used as a catalyst and a chemical building block. It is a strong base with pKa of the conjugate acid of 11.0. This is due to greater availability of the nitrogen lone pair.
cloperastine (3703-76-2)  
1-(2-((4-chloro-alpha-phenylbenzyl)oxy)ethyl)piperidine  ·  cloperastine hydrochloride
Cloperastine (INN) or cloperastin, also known as cloperastine hydrochloride (JAN) (brand names Hustazol, Nitossil, Seki) and cloperastine fendizoate (or hybenzoate), is an antitussive and antihistamine that is marketed as a cough suppressant in Japan, Hong Kong, and in some European countries. It was first introduced in 1972 in Japan, and then in Italy in 1981. The precise mechanism of action of cloperastine is not fully clear, but several different biological activities have been identified for the drug, of which include: ligand of the σ1 receptor (Ki = 20 nM) (likely an agonist), GIRK channel blocker (described as "potent"), antihistamine (Ki = 3.8 nM for the H1 receptor), and anticholinergic.
1-(3-Chlorophenyl)piperazine (6640-24-0)  
m-CPP  ·  1-(3-chlorophenyl)piperazine dihydrochloride  ·  m-chlorophenylpiperazine
meta-Chlorophenylpiperazine (mCPP) is a psychoactive drug of the phenylpiperazine class. It was initially developed in the late-1970s and used in scientific research before being sold as a designer drug in the mid-2000s. It has been detected in pills touted as legal alternatives to illicit stimulants in New Zealand and pills sold as "ecstasy" in Europe and the United States.
Related searches
Kappa agonists
Opioid receptor ligands
Drugs acting on the nervous system
Thiophenes
Opioids
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