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Kappa agonists, Opioids, Allyl compounds

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Alkenes (1)
Analgesics (1)
Cyclic compounds (1)
Cycloalkenes (1)
Cyclohexenes (1)
Dissociative drugs (1)
Drugs acting on the nervous system (1)
Opioid antagonists (1)
Opioid receptor ligands (1)
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Semisynthetic opioids (1)
Six-membered rings (1)

Nalorphine (62-67-9)  
Allylnormorphine  ·  Nalorphine Hydrochloride  ·  Lethidrone
Nalorphine (INN) (brand names Lethidrone, Nalline), also known as N-allylnormorphine, is a mixed opioid agonist–antagonist with opioid antagonist and analgesic properties. It was introduced in 1954 and was used as an antidote to reverse opioid overdose and in a challenge test to determine opioid dependence. It acts at two opioid receptors — the μ-opioid receptor (MOR) where it has antagonistic effects, and at the κ-opioid receptor (KOR) (Ki = 1.6 nM; EC50 = 483 nM; Emax = 95%) where it exerts high-efficacy partial agonist/near-full agonist characteristics.

Related Results:
Allyl ionone (79-78-7)  
allyl alpha-ionone
TENOCYCLIDINE (21500-98-1, 1867-65-8)  
Tenocyclidine (TCP) was discovered by a team at Parke Davis in the late 1950s. It is a dissociative anesthetic drug with psychostimulant and hallucinogenic effects. It is similar in effects to phencyclidine (PCP) but is considerably more potent.
2-Amino-1-phenylethanol (4561-43-7, 7568-93-6)  
beta Phenylethanolamine  ·  2-Hydroxyphenethylamine  ·  beta-Hydroxyphenethylamine
Phenylethanolamine (sometimes abbreviated PEOH), or β-hydroxyphenethylamine, is a trace amine with a structure similar to those of other trace phenethylamines as well as the catecholamine neurotransmitters dopamine, norepinephrine, and epinephrine. As an organic compound, phenylethanolamine is a β-hydroxylated phenethylamine that is also structurally related to a number of synthetic drugs in the substituted phenethylamine class. In common with these compounds, phenylethanolamine has strong cardiovascular activity and, under the name Apophedrin, has been used as a drug to produce topical vasoconstriction.
2,2,3-TRIMETHYLBUTANE (464-06-2)  
Triptane, or 2,2,3-trimethylbutane, is an organic chemical compound with the molecular formula C7H16 or (H3C-)3C-C(-CH3)2H. It is therefore an alkane, specifically the most compact and heavily branched of the heptane isomers, the only one with a butane (C4) backbone. Triptane is commonly used as an anti-knock additive in aviation fuels.
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Kappa agonists
Opioids
Allyl compounds
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