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Kappa agonists, Three-membered rings

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Analgesics (1)
Cyclic compounds (1)
Cycloalkanes (1)
Cyclopropanes (1)
Delta-opioid agonists (1)
Dissociative drugs (1)
Drugs acting on the nervous system (1)
Nervous system drug (1)
Opioid receptor ligands (1)
Opioids (1)
Psychoactive drugs (1)
Synthetic opioids (1)

CYCLORPHAN (4163-15-9)  
Cyclorphan is an opioid analgesic of the morphinan family that was never marketed. It acts as a μ-opioid receptor (MOR) weak partial agonist or antagonist, κ-opioid receptor (KOR) full agonist, and, to a much lesser extent, δ-opioid receptor (DOR) agonist (75-fold lower affinity relative to the KOR). The drug was first synthesized in 1964 by scientists at Research Corporation.

Related Results:
15532-75-9 (15532-75-9)  
TFMPP  ·  1-(m-trifluoromethylphenyl)piperazine  ·  1-(3-trifluoromethylphenyl)piperazine
3-Trifluoromethylphenylpiperazine (TFMPP) is a recreational drug of the piperazine chemical class. Usually in combination with its analogue benzylpiperazine (BZP), it is sold as an alternative to the illicit drug MDMA ("Ecstasy") under the name "Legal X".
ALPHA-PHELLANDRENE (4221-98-1, 1329-99-3, 99-83-2, 34448-33-4)  
alpha phellandrene, (S+)-isomer  ·  alpha phellandrene, (R)-isomer  ·  5-isopropyl-2-methyl-1,3-cyclohexadiene
Phellandrene is the name for a pair of organic compounds that have a similar molecular structure and similar chemical properties. α-Phellandrene and β-phellandrene are cyclic monoterpenes and are double-bond isomers. In α-phellandrene, both double bonds are endocyclic and in β-phellandrene, one of them is exocyclic.
WIN VI (98034-30-1)  
Win 52035  ·  WIN 52035-2  ·  5-(5-(4-(4,5-dihydro-2-oxazolyl)phenoxy)pentyl)-3-methylisoxazole
3,20-Allopregnanedione (566-65-4)  
5alpha-Pregnane-3,20-dione  ·  3,20-Allopregnanedione, (5beta,13alpha,17alpha)-Isomer  ·  5 alpha-Pregnane-3,20-dione
(+/-)-Epibatidine (140111-52-0)  
Epibatidine is a putative alkaloid that is secreted by the Ecuadoran frog Epipedobates anthonyi. It was discovered by John W. Daly in 1974, but its structure was not fully elucidated until 1992.
Azacyclonol (115-46-8)  
azacyclonol hydrochloride
Azacyclonol (trade names Ataractan, Calmeran, Frenoton, Frenquel, Psychosan), also known as γ-pipradrol, is a drug which is an ataractive; an agent which diminishes hallucinations in psychotic individuals. It has also been called a tranquilizer and antipsychotic, though these definitions are not accurate as it does not actually possess such properties. Despite being a positional isomer of pipradrol, it is not a psychostimulant, and instead has mild depressant effects.
2-METHYLPIPERIDINE (109-05-7)  
2-methylpiperidine hydrochloride  ·  2-pipecoline  ·  2-methylpiperidine, (+-)-isomer
3-(2-Aminopropyl)indole (299-26-3, 304-54-1)  
α-Methyltryptamine (abbreviated as αMT, AMT) is a psychedelic, stimulant, and entactogen drug of the tryptamine class. It was originally developed as an antidepressant by workers at Upjohn in the 1960s, and was used briefly as an antidepressant in Russia under the trade name Indopan before being discontinued.
TENOCYCLIDINE (21500-98-1, 1867-65-8)  
Tenocyclidine (TCP) was discovered by a team at Parke Davis in the late 1950s. It is a dissociative anesthetic drug with psychostimulant and hallucinogenic effects. It is similar in effects to phencyclidine (PCP) but is considerably more potent.
Compound VII (98033-68-2)  
WIN 53338  ·  WIN-53338  ·  WIN53338
clobenpropit (145231-45-4)  
S-(3-(4(5)-imidazolyl))propyl-N-(4-chlorobenzyl)isothiourea  ·  VUF-9153  ·  VUF 9153
Clobenpropit is a histamine H3 receptor antagonist. It has neuroprotective effects via stimulation of GABA release in the brain.
METYROSINE (672-87-7)  
Demser  ·  alpha Methyltyrosine  ·  alpha Methyl para tyrosine
Metirosine (INN and BAN; α-Methyltyrosine, Metyrosine USAN, AMPT) is an antihypertensive drug. It inhibits the enzyme tyrosine hydroxylase and, therefore, catecholamine synthesis, which, as a consequence, depletes the levels of the catecholamines dopamine, adrenaline and noradrenaline in the body.
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Kappa agonists
Three-membered rings
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