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Morpholines

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Morpholine (110-91-8, 1109-91-8, 61791-40-0, 110-91-8)  
morpholine hydrochloride  ·  morpholine phosphate (3:1)  ·  morpholine phosphonate (1:1)
Morpholine is an organic chemical compound having the chemical formula O(CH2CH2)2NH. This heterocycle features both amine and ether functional groups. Because of the amine, morpholine is a base; its conjugate acid is called morpholinium.
linezolid (165800-03-3)  
Linezolid is an antibiotic used for the treatment of infections caused by Gram-positive bacteria that are resistant to other antibiotics. Linezolid is active against most Gram-positive bacteria that cause disease, including streptococci, vancomycin-resistant enterococci (VRE), and methicillin-resistant Staphylococcus aureus (MRSA). The main uses are infections of the skin and pneumonia although it may be used for a variety of other infections including drug resistant tuberculosis.
timolol (26839-75-8, 26921-17-5)  
Timoptic  ·  Timolol Maleate  ·  Blocadren
Timolol is a medication used either by mouth or as eye drops. As eye drops it is used to treat increased pressure inside the eye such as in ocular hypertension and glaucoma. By mouth it is used for high blood pressure, chest pain due to insufficient blood flow to the heart, to prevent further complications after a heart attack, and to prevent migraines.
Bontril (634-03-7, 21784-30-5)  
Phendimetrazine (Bontril, Adipost, Anorex-SR, Appecon, Melfiat, Obezine, Phendiet, Plegine, Prelu-2, Statobex) is a stimulant drug of the morpholine chemical class used as an appetite suppressant.
phendimetrazine (634-03-7)  
phendimetrazine tartrate  ·  Bontril  ·  Hyrex
Phendimetrazine (Bontril, Adipost, Anorex-SR, Appecon, Melfiat, Obezine, Phendiet, Plegine, Prelu-2, Statobex) is a stimulant drug of the morpholine chemical class used as an appetite suppressant.
moclobemide (71320-77-9)  
Arima  ·  Manerix  ·  Aurorix
Moclobemide (sold as Amira, Aurorix, Clobemix , Depnil and Manerix) is a reversible inhibitor of monoamine oxidase A (RIMA) drug primarily used to treat depression and social anxiety. It is not approved for use in the United States, but is approved in other Western countries such as the UK and Australia (TGA approved in December 2000). It is produced by affiliates of the Hoffmann–La Roche pharmaceutical company.
phenmetrazine (134-49-6)  
Preludin  ·  Phenmetrazine Hydrochloride  ·  Defenmetrazin
Phenmetrazine (INN, USAN, BAN) (brand name Preludin, and many others) is a stimulant drug that was previously used as an appetite suppressant, but has since been withdrawn from the market. It was initially replaced by its analogue phendimetrazine which functions as a prodrug to phenmetrazine, but now it is rarely prescribed, due to concerns of abuse and addiction. Chemically, phenmetrazine is a substituted amphetamine with a morpholine ring.
Reboxetine (98769-81-4, 98819-76-2, 71620-89-8)  
Esreboxetine is a selective norepinephrine reuptake inhibitor which was under development by Pfizer for the treatment of neuropathic pain and fibromyalgia but failed to show significant benefit over currently available medications and was discontinued. It is the (S,S)-(+)-enantiomer of reboxetine and is even more selective in comparison. However, recently it has been shown that esreboxetine could be effective in fibromyalgia patients.
Gefitinib (184475-35-2)  
Gefitinib (ZD1839) (INN, , trade name Iressa) is a drug used for certain breast, lung and other cancers. Gefitinib is an EGFR inhibitor, like erlotinib, which interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells. Therefore, it is only effective in cancers with mutated and overactive EGFR.
mycophenolic acid (483-60-3, 24280-93-1)  
mycophenolate mofetil  ·  Cellcept  ·  myfortic
Mycophenolic acid, less accurately called mycophenolate, is an immunosuppressant drug used to prevent rejection in organ transplantation. It inhibits an enzyme needed for the growth of T cells and B cells. It was initially marketed as the prodrug mycophenolate mofetil (MMF) to improve oral bioavailability.
minaprine (25905-77-5)  
Cantor  ·  Agr 1240  ·  minaprine dihydrochloride
Minaprine (INN, USAN, BAN) (brand names Brantur, Cantor) is a monoamine oxidase inhibitor antidepressant drug that was used in France for the treatment of depression until it was withdrawn from the market in 1996 because it caused convulsions. A study found that it acts as a reversible inhibitor of MAO-A (RIMA) in rats. In a study it has also been found to weakly inhibit acetylcholinesterase in rat brain (striatum) homogenates.
doxapram (309-29-5)  
Dopram  ·  Doxapram Hydrochloride  ·  Genopharm Brand of Doxapram Hydrochloride
Doxapram hydrochloride (marketed as Dopram, Stimulex or Respiram) is a respiratory stimulant. Administered intravenously, doxapram stimulates an increase in tidal volume, and respiratory rate.
pramoxine (140-65-8)  
Prax  ·  pramoxine hydrochloride  ·  Tronothane
Pramocaine (INN and BAN, also known as pramoxine or pramoxine HCI) is a topical anesthetic discovered at Abbott Laboratories in 1953 and used as an antipruritic. During research and development, pramocaine hydrochloride stood out among a series of alkoxy aryl alkamine ethers as an especially good topical local anesthetic agent. Pharmacologic study revealed it to be potent and of low acute and subacute toxicity, well tolerated by most mucous membranes and of a low sensitizing index in humans.
MORICIZINE (31883-05-3)  
Ethmozine  ·  Ethmozin  ·  Moricizine Hydrochloride
Moracizine or moricizine and sold under the trade name Ethmozine, is an antiarrhythmic of class IC. It was used for the prophylaxis and treatment of serious and life-threatening ventricular arrhythmias, but was withdrawn in 2007 for commercial reasons.
4-Methylmorpholine (109-02-4)  
4-methylmorpholine hydrochloride  ·  4-methylmorpholine hydrobromide  ·  4-methylmorpholine sulfite (1:1)
N-Methylmorpholine is an organic base of intermediate strength. Its main use is as the starting material for preparing N-methylmorpholine N-oxide.
4432-31-9 (4432-31-9)  
MES compound  ·  4-morpholineethanesulfonate  ·  2-(N-morpholino)ethanesulfonic acid
2-Morpholinoethanesulfonic acid (4432-31-9)  
MES is the common name for the compound 2-(N-morpholino)ethanesulfonic acid. Its chemical structure contains a morpholine ring. It has a molecular weight of 195.2 and the chemical formula is C6H13NO4S.
Fenpropimorph (67564-91-4)  
4-(3-(4-(1,1-dimethylethyl)phenyl)-2-methylpropyl)-2,6-dimethylmorpholine
Nimorazole (6506-37-2)  
Esclama  ·  K 1900  ·  Pharmacia Brand of Nimorazole
Nimorazole (INN) is a nitroimidazole anti-infective. It is also being investigated for the treatment of head and neck cancer.
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