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Mu-opioid agonists, Alkaloids

Categories

Analgesics (3)
Drugs acting on the nervous system (3)
Euphoriants (3)
Opioid receptor ligands (3)
Opioids (3)
Psychoactive drugs (3)
Ethers (2)
Kappa agonists (2)
Morphine (2)
Natural opium alkaloids (2)
Opiates (2)
Opium (2)
Pharmaceuticals (1)

morphine (64-31-3, 57-27-2)  
Morphia  ·  Morphine Sulfate  ·  MS Contin
Morphine is a pain medication of the opiate variety which is found naturally in a number of plants and animals. It acts directly on the central nervous system (CNS) to decrease the feeling of pain. It can be taken for both acute pain and chronic pain.
Hodgkinsine (18210-71-4)  
Hodgkinsine is an alkaloid found in plants of the Psychotria genus, particularly Psychotria colorata, although it is also found in Psychotria lyciiflora and probably other species in this family, as well as in the related species Calycodendron milnei. Hodgkinsine has antiviral, antibacterial and antifungal effects, but has mainly been researched for the analgesic effects that it produces, and is thought to be one of the components responsible for the analgesic effects seen when Psychotria colorata is used in traditional medical practice in humans. It has been found to act as both a mu opioid agonist and an NMDA antagonist, both of which are mechanisms of action shared with commonly used painkillers (morphine and ketamine respectively, and which occur concurrently in the clinical analgesics tramadol and levorphanol).

Related Results:
ISOQUINOLINE (119-65-3)  
isoquinoline hydrochloride  ·  isoquinoline conjugate acid  ·  isoquinoline hydrobromide
Isoquinoline is a heterocyclic aromatic organic compound. It is a structural isomer of quinoline. Isoquinoline and quinoline are benzopyridines, which are composed of a benzene ring fused to a pyridine ring.
5-Nitroisoquinoline (607-32-9)  
5-nitroquinoline
1-METHYLISOQUINOLINE (1721-93-3, 58853-80-8)  
1-methylisoquinoline hydroiodide
Metofoline (14415-95-3, 180003-15-0, 2154-02-1)  
Metofoline ([[International nonproprietary name|INN), also known as methofoline (USAN), is an opioid analgesic drug discovered in the 1950s by a team of Swiss researchers at Hoffmann-La Roche. Methopholine is an isoquinoline derivative which is not structurally related to most other opioids. However, its structural similarity to papaverine is notable.
Eugenin (480-34-2)  
Eugenin is a chromone derivative, a phenolic compound found in cloves. It is also one of the compounds responsible for bitterness in carrots.
Compound VII (98033-68-2)  
WIN 53338  ·  WIN-53338  ·  WIN53338
1,2,3,4-Tetrahydroisoquinoline (91-21-4, 14099-81-1)  
tetrahydroisoquinoline  ·  1,2,3,4-tetrahydro-2-azanaphthalene  ·  HCl of 1,2,3,4-tetrahydroisoquinoline
Tetrahydroisoquinoline (TIQ) is an organic compound with the chemical formula C9H11N. Classified as a secondary amine, it is derived from isoquinoline by hydrogenation. It is a colorless viscous liquid that is miscible with most organic solvents.
Glaucine (475-81-0)  
glaucine phosphate (5:7), (+-)-isomer  ·  glaucine acetate, (+-)-isomer  ·  glaucine phosphate (2:3), (S)-isomer
Glaucine is an alkaloid found in several different plant species in the Papaveraceae family such as Glaucium flavum, Glaucium oxylobum and Corydalis yanhusuo, and in other plants like Croton lechleri in the family Euphorbiaceae. It has bronchodilator and antiinflammatory effects, acting as a PDE4 inhibitor and calcium channel blocker, and is used medically as an antitussive in some countries. Glaucine may produce side effects such as sedation, fatigue, and a hallucinogenic effect characterised by colourful visual images, and has been detected as a novel psychoactive drug.
Laudanosine (1699-51-0, 2688-77-9)  
Laudanosine or N-methyltetrahydropapaverine is a recognized metabolite of atracurium and cisatracurium. Laudanosine decreases the seizure threshold, and thus it can induce seizures if present at sufficient threshold concentrations; however such concentrations are unlikely to be produced consequent to chemodegradable metabolism of clinically administered doses of cisatracurium or atracurium. Laudanosine also occurs naturally in minute amounts (0.1%) in opium, from which it was first isolated in 1871.
1-PHENYLPIPERAZINE (92-54-6)  
phenylpiperazine  ·  phenylpiperazine monohydrochloride  ·  phenylpiperazine dihydrobromide
1-Phenylpiperazine is a simple chemical compound featuring a phenyl group bound to a piperazine ring. The suffix ‘-piprazole’ is sometimes used in the names of drugs to indicate they belong to this class. A number of phenylpiperazine derivatives are drugs, including: Pharmaceuticals: Research chemicals: Designer drugs:
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Mu-opioid agonists
Alkaloids
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