877-202-0205     support@chemchart.com     @chemchart
        
Sign In    Register
New Search

Similar to norketamine

Categories

Amines (6)
Bases (chemistry) (6)
Drugs acting on the nervous system (6)
Ketones (6)
Antidepressants (5)
Psychoactive drugs (5)
Psychoanaleptics (5)
Psychopharmacology (5)
Anesthetics (4)
Dissociative drugs (4)
General anesthetics (4)
Dopamine reuptake inhibitors (3)
Halides (3)
Monoamine reuptake inhibitors (3)
Organochlorides (3)
Organohalides (3)
Aromatic compounds (2)
Chloroarenes (2)
Cyclic compounds (2)
Analgesics (1)
Cycloalkenes (1)
Cyclohexenes (1)
Euphoriants (1)
Kappa agonists (1)
Mu-opioid agonists (1)
Nervous system drug (1)
Opioid receptor ligands (1)
Opioids (1)
Pharmaceuticals (1)
Six-membered rings (1)

Suppliers

Sigma Aldrich (1)

ketamine (6740-88-1)  
Ketamine Hydrochloride  ·  Ketalar  ·  Ketaset
Ketamine, sold under the brand name Ketalar among others, is a medication mainly used for starting and maintaining anesthesia. It induces a trance-like state while providing pain relief, sedation, and memory loss. Other uses include for chronic pain and for sedation in intensive care.
KETAMINE HYDROCHLORIDE (1867-66-9)  
Ketamine  ·  Ketalar  ·  Ketaset
Ketamine, sold under the brand name Ketalar among others, is a medication mainly used for starting and maintaining anesthesia. It induces a trance-like state while providing pain relief, sedation, and memory loss. Other uses include for chronic pain and for sedation in intensive care.
Esketamine (33643-46-8)  
Esketamine, sold under the brand names Ketanest and Ketanest S, also known as (S)-ketamine or S(+)-ketamine, is a general anesthetic and a dissociative hallucinogen. It is the S(+) enantiomer of the drug ketamine, which is an anesthetic and dissociative similarly. Esketamine acts primarily as a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist.
norketamine (35211-10-0)  
Norketamine, or N-desmethylketamine, is the major active metabolite of ketamine, which is formed mainly by CYP3A4. Similarly to ketamine, norketamine acts as a noncompetitive NMDA receptor antagonist (Ki = 1.7 µM and 13 µM for (S)-(+)-norketamine and (R)-(–)-norketamine, respectively), but is about 3–5 times less potent as an anesthetic in comparison. Also, similarly again to ketamine, norketamine binds to the μ- and κ-opioid receptors.
(R)-Ketamine (33643-49-1)  
Arketamine, also (R)-ketamine or (R)-(−)-ketamine, is the (R)-(−) enantiomer of ketamine. Similarly to racemic ketamine and esketamine, the S(+) enantiomer of ketamine, arketamine is biologically active; however, it is less potent as an NMDA receptor antagonist and anesthetic and thus has never been approved or marketed for clinical use as an enantiopure drug. Relative to esketamine, arketamine possesses 4–5 times lower affinity for the PCP site of the NMDA receptor.
5,6-Dehydronorketamine (57683-62-2)  
Dehydronorketamine (DHNK), or 5,6-dehydronorketamine, is a minor metabolite of ketamine which is formed by dehydrogenation of its metabolite norketamine. Though originally considered to be inactive, DHNK has been found to act as a potent and selective negative allosteric modulator of the α7-nicotinic acetylcholine receptor (IC50 = 55 nM). For this reason, similarly to hydroxynorketamine (HNK), it has been hypothesized that DHNK may have the capacity to produce rapid antidepressant effects.
Cyclohexanone, 2-amino-2-(2-chlorophenyl)-6-hydroxy- (81395-70-2)  
Hydroxynorketamine (HNK), or 6-hydroxynorketamine, is a minor metabolite of the anesthetic, dissociative, and antidepressant drug ketamine. It is formed by hydroxylation of the intermediate norketamine, another metabolite of ketamine. The major metabolite of ketamine is norketamine (80%).