Related to BUTACHLOR, Neurotoxins, Estrogens
Cyclic compounds (2)
Hormonal agents (2)
Sex hormones (2)
Endrin · Hexadrin
endosulfan (959-98-8, 33213-65-9, 115-29-7)
Thiodan · beta-Endosulfan · Thiodon
Endosulfan is an off-patent organochlorine insecticide and acaricide that is being phased out globally. The two isomers, endo and exo, are known popularly as I and II. Endosulfan sulfate is a product of oxidation containing one extra O atom attached to the S atom.
ZEARALENONE (17924-92-4, 36455-70-6)
F2 Toxin · F-2 Toxin · F 2 Toxin
Zearalenone (ZEN), also known as RAL and F-2 mycotoxin, is a potent estrogenic metabolite produced by some Fusarium and Gibberella species. Particularly, is produced by Fusarium graminearum, Fusarium culmorum, Fusarium cerealis, Fusarium equiseti, Fusarium verticillioides, and Fusarium incarnatum. Several Fusarium species produce toxic substances of considerable concern to livestock and poultry producers, namely deoxynivalenol, T-2 toxin, HT-2 toxin, diacetoxyscirpenol (DAS) and zearalenone.
T2 Toxin (21259-20-1)
Fusaritoxin · Fusariotoxin · T 2 Toxin
T-2 Mycotoxin (pronounced as 'Tee-Two') is a trichothecene mycotoxin. It is a naturally occurring mold byproduct of Fusarium spp. fungus which is toxic to humans and animals.
Tasosartan is an angiotensin II receptor antagonist. It was withdrawn from FDA review by the manufacturer after phase III clinical trials showed elevated transaminases (a sign of possible liver toxicity) in a significant number of participants given the drug.
Estradiol mustard (22966-79-6)
Estradiol mustard (developmental code name NSC-112259), also known as chlorphenacyl estradiol diester, as well as estradiol 3,17β-bis(4-(bis(2-chloroethyl)amino)phenyl)acetate, is a synthetic, steroidal estrogen and alkylating antineoplastic agent and a chlorphenacyl nitrogen mustard-coupled estrogen ester that was never marketed. It is selectively distributed into estrogen receptor (ER)-positive tissues such as ER-expressing tumors like those seen in breast and prostate cancers. For this reason, estradiol mustard and other cytostatic-linked estrogens like estramustine phosphate have reduced toxicity relative to non-linked nitrogen mustard alkylating antineoplastic agents.
estrone (19973-76-3, 53-16-7)
Folliculin · Kestrone · Wehgen
Estrone (E1), also spelled oestrone, is a steroid, a weak estrogen, and a minor female sex hormone. It is one of three major endogenous estrogens, the others being estradiol and estriol. Estrone, as well as the other estrogens, are synthesized from cholesterol and secreted mainly from the gonads, though they can also be formed from adrenal androgens in adipose tissue.
diethylstilbestrol (6898-97-1, 56-53-1, 22610-99-7, 64-67-5)
Stilbestrol · Distilbène · Stilbene Estrogen
Hexestrol · Hexestrol, (R-(R*,R*))-Isomer · Hexestrol, (R*,S*)-Isomer
SAXITOXIN (73603-72-2, 35523-89-8)
Saxitoxin (STX) is a potent neurotoxin and the best-known paralytic shellfish toxin (PST). Ingestion of saxitoxin, usually by consumption of shellfish contaminated by toxic algal blooms, is responsible for the human illness known as paralytic shellfish poisoning (PSP). The term saxitoxin originates from the genus name of the butter clam (Saxidomus) from which it was first isolated.
Dirigestran (33515-09-2, 6918-09-8, 9002-67-9, 9034-40-6)
GnRH · LHRH · Gonadotropin Releasing Hormone
Gonadorelin, also known as gonadotropin-releasing hormone (GnRH) and sold under the brand names Factrel, HRF, Kryptocur, Lutrelef, Lutrepulse, and Relefact among others, is a GnRH agonist which is used in fertility medicine and to treat amenorrhea and hypogonadism. It is also used in veterinary medicine. The drug is a pharmaceutical form of endogenous GnRH and is identical to it in chemical structure.
dienestrol (35495-11-5, 84-17-3, 13029-44-2)
Dienoestrol · Ortho Dienestrol · Dienestrol, (Z,E)-Isomer
Dienestrol (INN, USAN) (brand names Ortho Dienestrol, Dienoestrol, Dienoestrol Ortho, Sexadien, Denestrolin, Dienol, Dinovex, Follormon, Oestrodiene, Synestrol, numerous others), also known as dienoestrol (BAN), is a synthetic nonsteroidal estrogen of the stilbestrol group which is or was used to treat menopausal symptoms in the United States and Europe. It was introduced in the U.S. in 1947 by Schering as Synestrol and in France in 1948 as Cycladiene.
5 Pregnen 3 beta ol 20 one · 5-Pregnen-3-beta-ol-20-one
Pregnenolone (P5), or pregn-5-en-3β-ol-20-one, is an endogenous steroid and precursor/metabolic intermediate in the biosynthesis of most of the steroid hormones, including the progestogens, androgens, estrogens, glucocorticoids, and mineralocorticoids. In addition, pregnenolone is biologically active in its own right, acting as a neurosteroid.
Kepone, also known as chlordecone, is an organochlorine compound and a colourless solid. This compound is a controversial insecticide related to Mirex and DDT. Its use was so disastrous that it is now prohibited in the western world, but only after many millions of kilograms had been produced.
estradiol benzoate (50-50-0)
Eston-B · 17beta-estradiol-3-benzoate · estradiol 3-benzoate
Estradiol benzoate, sold under the brand name Progynon-B among others, is a medication which is used in hormone therapy such as for menopausal symptoms and in veterinary medicine. It is given by injection into muscle. Side effects of estradiol benzoate include breast tenderness, breast enlargement, nausea, headache, and fluid retention.
Estriol · Epiestriol · (16alpha,17beta)-Estra-1,3,5(10)-Triene-3,16,17-Triol
Epiestriol (INN) (brand names Actriol, Arcagynil, Klimadoral), or epioestriol (BAN), also known as 16β-epiestriol or simply 16-epiestriol as well as 16β-hydroxy-17β-estradiol, is a minor and weak endogenous estrogen, and the 16β-epimer of estriol (which is 16α-hydroxy-17β-estradiol). Epiestriol is (or has previously been) used clinically in the treatment of acne. In addition to its estrogenic actions, epiestriol has been found to possess significant anti-inflammatory properties without glycogenic activity or immunosuppressive effects, an interesting finding that is in contrast to conventional anti-inflammatory steroids like hydrocortisone (a glucocorticoid).
hexestrol (84-16-2, 5635-50-7)
Hexestrol, (R-(R*,R*))-Isomer · Hexestrol, (R*,S*)-Isomer · Dihydrodiethylstilbestrol
Hexestrol (INN) (brand names Synestrol, Synoestrol, Estrifar, Estronal, numerous others), also known as hexanestrol, hexoestrol, and dihydrodiethylstilbestrol, is a synthetic nonsteroidal estrogen of the stilbestrol group related to diethylstilbestrol which was used to treat estrogen deficiency. Oil solution of hexestrol is still manufactured in Russia under trade name Синэстрол. Hexestrol has also been available and used in ester form, including as hexestrol diacetate, hexestrol dicaprylate, hexestrol diphosphate, and hexestrol dipropionate. Hexestrol has approximately 302% and 234% of the affinity of estradiol at the ERα and ERβ, respectively.
estradiol cypionate (313-06-4)
Depo-estradiol · estradiol 17 beta-cyclopentylpropionate · estradiol 17 beta-cypionate
Estradiol cypionate, sold under the brand name Depo-Estradiol among others, is a medication which is used in hormone therapy such as for menopausal symptoms and in hormonal birth control. It is given by injection into muscle. Side effects of estradiol cypionate include breast tenderness, breast enlargement, nausea, headache, and fluid retention.