Cyclic compounds (6)
Alpha blockers (1)
Beta blockers (1)
Designer drugs (1)
Food Additives (1)
Organic compound (1)
Sigma Aldrich (33)
Matrix Scientific (25)
Oakwood Chemical (20)
AK Scientific (18)
TCI Chemicals (17)
Apollo Scientific (14)
Frontier Scientific (13)
Propiomazine (Largon, Propavan, Indorm, Serentin, Dorevane, Dorevan) is an antihistamine blocking H1 receptors. It is used to treat insomnia, and to produce sleepiness or drowsiness and to relieve anxiety before or during surgery or other procedures and in combination with analgetics also during labor. Propiomazine is a phenothiazine, but is not used as a neuroleptic because it does not block dopamine receptors well.
Dosulepin, also known as dothiepin and sold under the brand name Prothiaden among others, is a tricyclic antidepressant (TCA) which is used in the treatment of depression. Dosulepin was once the most frequently prescribed antidepressant in the United Kingdom, but it is no longer widely used due to its relatively high toxicity in overdose without therapeutic advantages over other TCAs. It acts as a serotonin–norepinephrine reuptake inhibitor (SNRI) and also has other activities including antihistamine, antiadrenergic, antiserotonergic, anticholinergic, and sodium channel-blocking effects.
2-diphenylmethylpiperidine hydrochloride, (R)-isomer · 2-diphenylmethylpiperidine, (R)-isomer · desoxypipradrol
Desoxypipradrol, also known as 2-diphenylmethylpiperidine (2-DPMP), acts as a norepinephrine-dopamine reuptake inhibitor (NDRI) developed by Ciba in the 1950s.
6959-47-3 (6959-47-3, 110656-58-1)
2-chloromethylpyridine hydrochloride · 2-CMP · 2-chloromethylpyridine
A carbodiimide or a methanediimine is a functional group consisting of the formula RN=C=NR. Carbodiimides hydrolyze to form ureas, which makes them uncommon in nature. From the perspective of small molecule activation, carbodiimides are isoelectronic with carbon dioxide.
BICIFADINE (66504-75-4, 71195-57-8)
Bicifadine (DOV-220,075) is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) discovered at American Cyanamid as an analgesic drug candidate, and licensed to DOV Pharmaceutical in 1998 after American Cyanamid was acquired by Wyeth. In January 2007, Dov licensed the rights to bicifadine to XTL Biopharmaceuticals after bicifadine failed in a Phase III clinical trial for chronic lower back pain. XTL ran a PhaseIIb clinical trial for pain caused by diabetic neuropathy, which failed in 2008; XTL terminated the agreement in 2010.
para-nitrophenylhydrazine · 4-nitrophenylhydrazine hydrochloride · (4-nitrophenyl)hydrazine
MTHPA (42498-58-8, 26590-20-5)
2-methyl-3-(2,4,5-trihydroxyphenyl)alanine · 2-methyl-3-(2,4,5-trihydroxyphenyl)alanine hydrochloride, (D-Tyr)-isomer · 2-methyl-3-(2,4,5-trihydroxyphenyl)alanine hydrochloride, (DL-Tyr)-isomer
deacetyldiltiazem, (cis)-isomer · desacetyldiltiazem · deacetyldiltiazem hydrochloride, (cis-(+-))-isomer
Ambodryl hydrochloride (1808-12-4)
bromodiphenhydramine · ambodryl · bromodiphenhydramine hydrochloride
N-(2-hydroxyethyl)-2,5-(14C)-pyrrolidine · epolamine · N-(2-hydroxyethyl)pyrrolidine
D 617 · D-617 · 1-isopropyl-1-N-methylpropylamino-(3,4-dimethoxyphenyl)acetonitrile
phenylglutarimide · 2-(2-(diethylamino)ethyl)-2-phenylglutarimide · phenglutarimide hydrochloride
Phenglutarimide (brand names Aturbal, Aturbane) is an anticholinergic used as an antiparkinsonian agent.
Pyrovalerone (Centroton, 4-Methyl-β-keto-prolintane, Thymergix, O-2371) is a psychoactive drug with stimulant effects via acting as a norepinephrine-dopamine reuptake inhibitor (NDRI), and is used for the clinical treatment of chronic fatigue or lethargy and as an anorectic or appetite suppressant for weight loss purposes. It was developed in the late 1960s and has since been used in France and several other European countries, and although pyrovalerone is still occasionally prescribed, it is used infrequently due to problems with abuse and dependence. It is closely related on a structural level to a number of other stimulants, such as MDPV and prolintane (Promotil, Katovit).
Lupinine (10248-30-3, 486-70-4)
lupinine hydrochloride, (1R-trans)-isomer · 1S-cis-octahydro-2H-quinolizine-1-methanol · lupinine, (1S-cis)-isomer
Lupinine is a bitter tasting quinolizidine alkaloid present in Lupinus species (lupins), plants of the family Fabaceae. The scientific literature contains many reports on the isolation and synthesis of this compound. The characteristically bitter taste of lupin beans, attributable to the alkaloids which they contain, renders them unsuitable for human and animal consumption.
hydrastine, (R-(R*,R*))-isomer · hydrastine, (R-(R*,S*))-isomer · isocoryne
Hydrastine is an alkaloid which was discovered in 1851 by Alfred P. Durand. Hydrolysis of hydrastine yields hydrastinine, which was patented by Bayer as a haemostatic drug during the 1910s.