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Organofluorides, Five-membered rings

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Cyclic compounds (13)
Halides (13)
Organohalides (13)
Tetrahydrofurans (6)
Alcohols (4)
Pharmaceuticals (4)
Antimetabolites (3)
Antineoplastic and immunomodulating drugs (3)
Antineoplastic antimetabolites (3)
Antineoplastic drugs (3)
Organoiodides (3)
Oxathiolanes (3)
Pyrimidine antagonists (3)
Dihydrofurans (2)
Tetrazoles (2)
Acids (1)
Carboxylic acids (1)
Chalcogenides (1)
Ethers (1)
Organic acids (1)
Sulfides (1)

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Emtricitabine (143491-57-0, 143491-54-7)  
Emtricitabine (commonly called FTC, systematic name 2',3'-dideoxy-5-fluoro-3'-thiacytidine), with trade name Emtriva (formerly Coviracil), is a nucleoside reverse transcriptase inhibitor (NRTI) for the prevention and treatment of HIV infection in adults and children. Emtricitabine is also marketed in a fixed-dose combination with tenofovir (Viread) under the brand name Truvada. A fixed-dose triple combination of emtricitabine, tenofovir and efavirenz (Sustiva, marketed by Bristol-Myers Squibb) was approved by the U.S.
tegafur (82294-77-7, 17902-23-7)  
Ftorafur  ·  FT 207  ·  1-(Tetrahydro-2-furanyl)-5-fluorouracil
Tegafur (INN, BAN, USAN) is a chemotherapeutic prodrug of 5-fluorouracil (5-FU) used in the treatment of cancers. It is a component of the combination drug tegafur/uracil. When metabolised, it becomes 5-FU.
Flomoxef (99665-00-6)  
Flomoxef (INN) is an oxacephem antibiotic. It has been classified as second-generation and fourth-generation.
Elvucitabine (181785-84-2)  
Elvucitabine is an experimental nucleoside reverse transcriptase inhibitor (NRTI), developed by Achillion Pharmaceuticals, Inc. for the treatment of HIV infection. Elvucitabine belongs to a class (group) of HIV drugs called nucleoside reverse transcriptase inhibitors (NRTIs).
Dexelvucitabine (134379-77-4)  
Dexelvucitabine is a failed experimental agent for the management of HIV infection. Dexelvucitabine is a cytidine nucleoside analog and nucleoside reverse transcriptase inhibitor. It was found to inhibit HIV-1 replication in vitro and during Phase II clinical trials, it was found to decrease mean viral load in patients with HIV.
FIALURIDINE (69123-98-4)  
Fialuridine, or 1-(2-deoxy-2-fluoro-1-D-arabinofuranosyl)-5-iodouracil (FIAU), is a nucleoside analogue that was investigated as a potential therapy for hepatitis B virus infection. In a 1993 clinical study at the NIH, unexpected toxicity led to the death of 5 out of 15 patients from liver failure associated with lactic acidosis; two further participants required liver transplantation. This toxicity was unusual in that it was not predicted by animal studies.
Cefazaflur (58665-96-6)  
Cefazaflur (INN) is a first-generation cephalosporin antibiotic.
5FC-(+)-beta (137530-41-7)  
Racivir is an experimental nucleoside reverse transcriptase inhibitor (NRTI), developed by Pharmasset for the treatment of HIV. It is the enantiomer of emtricitabine, a widely used NRTI, meaning that the two compounds are mirror images of each other.

Related Results:
2,5-Dimethyl-1H-pyrrole (625-84-3)  
2,5-dimethylpyrrole
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Organofluorides
Five-membered rings
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