Kappa agonists (3)
Sigma Aldrich (1)
TCI Chemicals (1)
Matrine is an alkaloid found in plants from the Sophora genus. It has a variety of pharmacological effects, including anti-cancer effects, as well as κ-opioid and μ-opioid receptor agonism. Matrine possesses strong antitumor activities in vitro and in vivo.
Bulbocapnine (632-47-3, 298-45-3)
Bulbocapnine is an alkaloid found in Corydalis (Papaveraceae) and Dicentra, plants in the family Fumariaceae that can cause fatal poisoning in sheep and cattle. It has been shown to act as an acetylcholinesterase inhibitor, and inhibits biosynthesis of dopamine via inhibition of the enzyme tyrosine hydroxylase. According to the Dorlands Medical Dictionary, it "inhibits the reflex and motor activities of striated muscle.
Rhoeadine (rheadine) is an alkaloid derived from the flowers of the corn poppy (Papaver rhoeas). It is used as mild sedative and mild antitussive. It has been studied and shown promise in the treatment of morphine dependence.
1,2-Diphenylethane (103-29-7, 38888-98-1)
1,2-dihydrostilbene · 1,1'-(1,2-ethanediyl)bis(benzene)
Bibenzyl (1,2-diphenylethane) is an aromatic chemical compound that can be considered a derivative of ethane in which one phenyl group is attached to each carbon atom.
indole hydrochloride · indole, 14C-labeled
Indole is an aromatic heterocyclic organic compound with formula C8H7N. It has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring. Indole is widely distributed in the natural environment and can be produced by a variety of bacteria.