Polycyclic organic compounds, Alkaloid, Cyclic compounds, Alkaloids, Heterocyclic compounds (4 or more rings), Heterocyclic compounds, Drugs acting on the nervous system
Kappa agonists (3)
Sigma Aldrich (1)
TCI Chemicals (1)
Matrine is an alkaloid found in plants from the Sophora genus. It has a variety of pharmacological effects, including anti-cancer effects, as well as κ-opioid and μ-opioid receptor agonism. Matrine possesses strong antitumor activities in vitro and in vivo.
Bulbocapnine (632-47-3, 298-45-3)
Bulbocapnine is an alkaloid found in Corydalis (Papaveraceae) and Dicentra, plants in the family Fumariaceae that can cause fatal poisoning in sheep and cattle. It has been shown to act as an acetylcholinesterase inhibitor, and inhibits biosynthesis of dopamine via inhibition of the enzyme tyrosine hydroxylase. According to the Dorlands Medical Dictionary, it "inhibits the reflex and motor activities of striated muscle.