Polycyclic organic compounds, Cholinergics, Heterocyclic compounds, aksci.com, Heterocyclic compounds (bridged-ring)
Cyclic compounds (1)
Varenicline (trade name Chantix and Champix), is a prescription medication used to treat nicotine addiction. It both reduces cravings for and decreases the pleasurable effects of cigarettes and other tobacco products. It is a high-affinity partial agonist for the α4β2 nicotinic acetylcholine receptor subtype (nACH) that leads to the release of dopamine in the nucleus accumbens when activated, and therefore, has the capacity to reduce the feelings of craving and withdrawal caused by smoking cessation.
Rosefuran (3-methyl-2-prenylfuran) is a liquid boiling at 103-104 °C (at 50 mm Hg), with a density of 0.9089 g/cm3 (at 30 °C), less than that of water. It is an aroma chemical which is a minor constituent of the aroma of the rose (Rosa damascene). Rosefuran is a 2,3-disubstituted furan (3-methyl-2-(3-methyl-2-buten-1-yl)furan).
Perillene is a natural monoterpene that consists of a furan ring with a six-carbon homoprenyl side chain. Perillene is a component of the essential oil obtained by extraction of the leaves of Perilla frutescens. Perillene has also been obtained by steam distillation of the leaves of Perilla frutescens.
2,5-Dimethylfuran is a heterocyclic compound with the formula (CH3)2C4H2O. Although often abbreviated DMF, it should not be confused with dimethylformamide. A derivative of furan, this simple compound is a potential biofuel, being derivable from cellulose.
4-Aminoquinoline is a form of aminoquinoline with the amino group at the 4-position of the quinoline. A variety of derivatives of 4-aminoquinoline are antimalarial agents useful in treating erythrocytic plasmodial infections. Examples include amodiaquine, chloroquine, and hydroxychloroquine.