Cyclic compounds (6)
Spiro compounds (2)
Zosuquidar Trihydrochloride (167465-36-3)
Zosuquidar (also LY-335979) is an experimental antineoplastic drug. In 2010, it was announced that a phase III trial for the treatment of acute myeloid leukemia (AML) and myelodysplastic syndrome did not meet its primary endpoint and Eli Lilly discontinued its development. Zosquidir inhibits P-glycoproteins.
Spiropentane is a hydrocarbon with formula C5H8. It is the simplest spiro-connected cycloalkane, a triangulane. It took several years after the discovery in 1887 until the structure of the molecule was determined.According to the nomenclature rules for spiro compounds, the systematic name is spiro[2.2]pentane.
Thujene (or α-thujene) is a natural organic compound classified as a monoterpene. It is found in the essential oils of a variety of plants, and contributes pungency to the flavor of some herbs such as Summer savory. The term thujene usually refers to α-thujene.
Cuneane (C8H8, Pentacyclo[188.8.131.52 2,4.03,7.06,8]octane) is a saturated hydrocarbon. Its name is derived from the Latin cuneus, meaning a wedge. Cuneane may be produced from cubane by metal-ion-catalyzed σ-bond rearrangement.
Cadalene or cadalin (4-isopropyl-1,6-dimethylnaphthalene) is a polycyclic aromatic hydrocarbon with a chemical formula C15H18 and a cadinane skeleton. It is derived from generic sesquiterpenes, and ubiquitous in essential oils of many higher plants. Cadalene, together with retene, simonellite and ip-iHMN, is a biomarker of higher plants, which makes it useful for paleobotanic analysis of rock sediments.