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Polycyclic organic compounds, Heterocyclic compounds

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Cyclic compounds (40)
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Asenapine (65576-45-6)  
ORG 5222  ·  saphris  ·  asenapine maleate
Asenapine, sold under the trade names Saphris and Sycrest, is an atypical antipsychotic developed for the treatment of schizophrenia and acute mania associated with bipolar disorder. It was chemically derived via altering the chemical structure of the tetracyclic (atypical) antidepressant, mianserin.
Lurasidone (367514-88-3, 367514-87-2)  
Lurasidone (trade name Latuda) is an atypical antipsychotic developed by Dainippon Sumitomo Pharma and marketed by Sunovion in the U.S. It has been an FDA approved treatment for schizophrenia since 2010 and for treating depressive episodes in adults with bipolar I disorder since 2013. It can be used alone or in combination with mood stabilizers such as lithium or valproate (e.g., Depakote).
Varenicline (249296-44-4)  
Varenicline (trade name Chantix and Champix), is a prescription medication used to treat nicotine addiction. It both reduces cravings for and decreases the pleasurable effects of cigarettes and other tobacco products. It is a high-affinity partial agonist for the α4β2 nicotinic acetylcholine receptor subtype (nACH) that leads to the release of dopamine in the nucleus accumbens when activated, and therefore, has the capacity to reduce the feelings of craving and withdrawal caused by smoking cessation.
CYTISINE (485-35-8)  
Tsitizin  ·  cytisine hydrochloride, hydrate  ·  cytisine hydrochloride
Cytisine, also known as baptitoxine and sophorine, is an alkaloid that occurs naturally in several plant genera, such as Laburnum and Cytisus of the family Fabaceae. It has been used medically to help with smoking cessation. Its molecular structure has some similarity to that of nicotine and it has similar pharmacological effects.
podophyllotoxin (4354-76-1, 477-47-4, 518-28-5)  
Podofilox  ·  Epipodophyllotoxin  ·  Condylox
Podophyllotoxin (PPT), also known as podofilox, is a medical cream that is used to treat genital warts and molluscum contagiosum. It is not recommended in HPV infections without external warts. It can be applied either by a healthcare provider or the person themselves.
vincamine (1617-90-9)  
Vincapront  ·  Devincan  ·  Pervincamine
Vincamine is a monoterpenoid indole alkaloid found in the leaves of Vinca minor (lesser periwinkle), comprising about 25-65% of the indole alkaloids found in Vinca minor by weight. It can be synthesized from related alkaloids.
Isovincamine (6835-99-0)  
Vincamine  ·  Vincapront  ·  Devincan
Dihydroartemisinin (81496-81-3, 71939-50-9)  
Dihydroartemisinin (also known as dihydroqinghaosu, artenimol or DHA) is a drug used to treat malaria. Dihydroartemisinin is the active metabolite of all artemisinin compounds (artemisinin, artesunate, artemether, etc.) and is also available as a drug in itself. It is a semi-synthetic derivative of artemisinin and is widely used as an intermediate in the preparation of other artemisinin-derived antimalarial drugs.
artemisinin (63968-64-9)  
qinghaosu  ·  quinghaosu  ·  artemisinine
Artemisinin, also known as qinghao su (Chinese: 青蒿素), and its semi-synthetic derivatives are a group of drugs used against Plasmodium falciparum malaria. It was discovered by Tu Youyou, a Chinese scientist, who was awarded half of the 2015 Nobel Prize in Medicine for her discovery. Treatments containing an artemisinin derivative (artemisinin-combination therapies, ACTs) are now standard treatment worldwide for P.
Epipodophyllotoxin (4375-07-9)  
Epipodophyllotoxins are substances naturally occurring in the root of American Mayapple plant (Podophyllum peltatum). Some epipodophyllotoxin derivatives are currently used in the treatment of cancer. These include etoposide and teniposide.
Troeger's base (529-81-7)  
Tröger's base is an organic compound with the formula (CH3C6H4NCH2)2CH2. It is a white solid that is soluble in polar organic solvents. It is a diamine, which exhibits chirality due to the presence of two bridgehead stereogenic nitrogen atoms.
Matrine (519-02-8)  
Matrine is an alkaloid found in plants from the Sophora genus. It has a variety of pharmacological effects, including anti-cancer effects, as well as κ-opioid and μ-opioid receptor agonism. Matrine possesses strong antitumor activities in vitro and in vivo.
AC1LD383 (63968-64-9)  
Artemisinin, also known as qinghao su (Chinese: 青蒿素), and its semi-synthetic derivatives are a group of drugs used against Plasmodium falciparum malaria. It was discovered by Tu Youyou, a Chinese scientist, who was awarded half of the 2015 Nobel Prize in Medicine for her discovery. Treatments containing an artemisinin derivative (artemisinin-combination therapies, ACTs) are now standard treatment worldwide for P.
Vinburnine (2580-88-3, 4880-88-0)  
eburnamonine  ·  Cervoxan  ·  (-)-eburnamonine
Vinburnine (or eburnamonine, Vincamone) is a vasodilator. Vincamone is a vinca alkaloid and a metabolite of vincamine.
(-)-Eburnamonine (2580-88-3, 4880-88-0)  
eburnamonine  ·  Cervoxan  ·  eburnamonine monohydrochloride, (3alpha,16alpha)-isomer
Tephrosin (76-80-2)  
Tephrosin is rotenoid. It is a natural fish poison found in the leaves and seeds of Tephrosia purpurea and T. vogelii.
Bulbocapnine (632-47-3, 298-45-3)  
Bulbocapnine is an alkaloid found in Corydalis (Papaveraceae) and Dicentra, plants in the family Fumariaceae that can cause fatal poisoning in sheep and cattle. It has been shown to act as an acetylcholinesterase inhibitor, and inhibits biosynthesis of dopamine via inhibition of the enzyme tyrosine hydroxylase. According to the Dorlands Medical Dictionary, it "inhibits the reflex and motor activities of striated muscle.
Artenimol (71939-50-9)  
Dihydroartemisinin (also known as dihydroqinghaosu, artenimol or DHA) is a drug used to treat malaria. Dihydroartemisinin is the active metabolite of all artemisinin compounds (artemisinin, artesunate, artemether, etc.) and is also available as a drug in itself. It is a semi-synthetic derivative of artemisinin and is widely used as an intermediate in the preparation of other artemisinin-derived antimalarial drugs.
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Polycyclic organic compounds
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