Cyclic compounds (2)
Bulbocapnine (632-47-3, 298-45-3)
Bulbocapnine is an alkaloid found in Corydalis (Papaveraceae) and Dicentra, plants in the family Fumariaceae that can cause fatal poisoning in sheep and cattle. It has been shown to act as an acetylcholinesterase inhibitor, and inhibits biosynthesis of dopamine via inhibition of the enzyme tyrosine hydroxylase. According to the Dorlands Medical Dictionary, it "inhibits the reflex and motor activities of striated muscle.
2-METHYLNAPHTHALENE (7419-61-6, 91-57-6)
2-methylnaphthalene, methyl-13C-labeled · 2-methylnaphthalene, lithium salt, ion(1-) · 2-methylnaphthalene, naphthalene-1-(13)C-labeled
2-Methylnaphthalene is a polycyclic aromatic hydrocarbon (PAH). On February 22, 2014, NASA announced a greatly upgraded database for detecting and monitoring PAHs, including 2-methylnaphthalene, in the universe. According to NASA scientists, over 20% of the carbon in the universe may be associated with PAHs, possible starting materials for the formation of life.
Tasosartan is an angiotensin II receptor antagonist. It was withdrawn from FDA review by the manufacturer after phase III clinical trials showed elevated transaminases (a sign of possible liver toxicity) in a significant number of participants given the drug.
Biphenyl (92-52-4, 68409-73-4)
diphenyl · diphenyl, 14C-labeled
Biphenyl (or diphenyl or phenylbenzene or 1,1′-biphenyl or lemonene) is an organic compound that forms colorless crystals. Particularly in older literature, compounds containing the functional group consisting of biphenyl less one hydrogen (the site at which it is attached) may use the prefixes xenyl or diphenylyl. It has a distinctively pleasant smell.
2,6-DIPN · 2,6-disopropylnaphtalene
2,6-Diisopropylnaphthalene (2,6-DIPN) is structurally similar to other plant growth regulators commonly found in plant tissues, and seems to help inhibit the sprouting of potatoes during storage. 2,6-DIPN is intended for use in the manufacturing of pesticide products intended to prevent sprouting of stored potatoes.
1-NITROPYRENE (63021-86-3, 5522-43-0)
1-Nitropyrene is a by-product of combustion and is the predominant nitrated polycyclic aromatic hydrocarbon (pyrene) emitted in a diesel engine. 1-Nitropyrene is listed as an IARC Group 2B carcinogen, indicating it is possibly carcinogenic to humans.