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Polycyclic organic compounds, Organofluorides, Three-membered rings, Antineoplastic drugs, Pharmaceuticals

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Antineoplastic and immunomodulating drugs (1)
Cyclic compounds (1)
Cycloalkanes (1)
Cyclopropanes (1)
Experimental cancer drugs (1)
Halides (1)
Organohalides (1)
Piperazines (1)
Six-membered rings (1)
Tetracyclic compounds (1)

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Matrix Scientific (1)

Zosuquidar Trihydrochloride (167465-36-3)  
Zosuquidar (also LY-335979) is an experimental antineoplastic drug. In 2010, it was announced that a phase III trial for the treatment of acute myeloid leukemia (AML) and myelodysplastic syndrome did not meet its primary endpoint and Eli Lilly discontinued its development. Zosquidir inhibits P-glycoproteins.

Related Results:
Biphenyl (92-52-4, 68409-73-4)  
diphenyl  ·  diphenyl, 14C-labeled
Biphenyl (or diphenyl or phenylbenzene or 1,1′-biphenyl or lemonene) is an organic compound that forms colorless crystals. Particularly in older literature, compounds containing the functional group consisting of biphenyl less one hydrogen (the site at which it is attached) may use the prefixes xenyl or diphenylyl. It has a distinctively pleasant smell.
2-METHYLNAPHTHALENE (7419-61-6, 91-57-6)  
2-methylnaphthalene, methyl-13C-labeled  ·  2-methylnaphthalene, lithium salt, ion(1-)  ·  2-methylnaphthalene, naphthalene-1-(13)C-labeled
2-Methylnaphthalene is a polycyclic aromatic hydrocarbon (PAH). On February 22, 2014, NASA announced a greatly upgraded database for detecting and monitoring PAHs, including 2-methylnaphthalene, in the universe. According to NASA scientists, over 20% of the carbon in the universe may be associated with PAHs, possible starting materials for the formation of life.
1-METHYLNAPHTHALENE (90-12-0, 1321-94-4)  
1-Methylnaphthalene is a polycyclic aromatic hydrocarbon (PAH). It has a cetane number of zero, and was previously used as the lower reference for cetane number. However, due to the expense and handling difficulty of 1-methylnaphthalene, it was replaced in this capacity by isocetane, with a CN of 15.
CHRYSENE (65996-93-2, 50-32-8, 218-01-9)  
Chrysene is a polycyclic aromatic hydrocarbon (PAH) with the molecular formula C 18H 12 that consists of four fused benzene rings. It is a natural constituent of coal tar, from which it was first isolated and characterized. It is also found in creosote at levels of 0.5-6 mg/kg.
TASOSARTAN (145733-36-4)  
Tasosartan is an angiotensin II receptor antagonist. It was withdrawn from FDA review by the manufacturer after phase III clinical trials showed elevated transaminases (a sign of possible liver toxicity) in a significant number of participants given the drug.
1,1,1,2-TETRACHLOROETHANE (23425-39-0, 630-20-6)  
1,1,1,2-Tetrachloroethane is a chlorinated hydrocarbon. It is a colorless liquid with a sweet chloroform-like odor. It is used as a solvent and in the production of wood stains and varnishes.
FLUORENE (2299-68-5, 86-73-7)  
9H-fluorene
Fluorene , or 9H-fluorene, is a polycyclic aromatic hydrocarbon. It forms white crystals that exhibit a characteristic, aromatic odor similar to that of naphthalene. It is combustible.
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Polycyclic organic compounds
Organofluorides
Three-membered rings
Antineoplastic drugs
Pharmaceuticals
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