Polycyclic organic compounds, Organofluorides, Three-membered rings, Antineoplastic drugs, Piperazines, Antineoplastic and immunomodulating drugs
Cyclic compounds (1)
Zosuquidar Trihydrochloride (167465-36-3)
Zosuquidar (also LY-335979) is an experimental antineoplastic drug. In 2010, it was announced that a phase III trial for the treatment of acute myeloid leukemia (AML) and myelodysplastic syndrome did not meet its primary endpoint and Eli Lilly discontinued its development. Zosquidir inhibits P-glycoproteins.
4-Aminoquinoline is a form of aminoquinoline with the amino group at the 4-position of the quinoline. A variety of derivatives of 4-aminoquinoline are antimalarial agents useful in treating erythrocytic plasmodial infections. Examples include amodiaquine, chloroquine, and hydroxychloroquine.