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Polycyclic organic compounds, aksci.com, Psychoactive drugs, Neurotoxins

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Cholinergics (1)
Cyclic compounds (1)
Drugs acting on the nervous system (1)
Heterocyclic compounds (1)
Heterocyclic compounds (bridged-ring) (1)
Nicotinic agonists (1)
Parasympathomimetics (1)
Pharmaceuticals (1)

Varenicline (249296-44-4)  
Varenicline (trade name Chantix and Champix), is a prescription medication used to treat nicotine addiction. It both reduces cravings for and decreases the pleasurable effects of cigarettes and other tobacco products. It is a high-affinity partial agonist for the α4β2 nicotinic acetylcholine receptor subtype (nACH) that leads to the release of dopamine in the nucleus accumbens when activated, and therefore, has the capacity to reduce the feelings of craving and withdrawal caused by smoking cessation.

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TASOSARTAN (145733-36-4)  
Tasosartan is an angiotensin II receptor antagonist. It was withdrawn from FDA review by the manufacturer after phase III clinical trials showed elevated transaminases (a sign of possible liver toxicity) in a significant number of participants given the drug.
STP (hallucinogen) (15588-95-1)  
2,5-Dimethoxy-4-methylamphetamine (DOM; known on the street as STP, standing for "Serenity, Tranquility and Peace") is a psychedelic and a substituted amphetamine. It was first synthesized by Alexander Shulgin, and later reported in his book PiHKAL: A Chemical Love Story. DOM is classified as a Schedule I substance in the United States, and is similarly controlled in other parts of the world.
Biphenyl (92-52-4, 68409-73-4)  
diphenyl  ·  diphenyl, 14C-labeled
Biphenyl (or diphenyl or phenylbenzene or 1,1′-biphenyl or lemonene) is an organic compound that forms colorless crystals. Particularly in older literature, compounds containing the functional group consisting of biphenyl less one hydrogen (the site at which it is attached) may use the prefixes xenyl or diphenylyl. It has a distinctively pleasant smell.
2-METHYLNAPHTHALENE (7419-61-6, 91-57-6)  
2-methylnaphthalene, methyl-13C-labeled  ·  2-methylnaphthalene, lithium salt, ion(1-)  ·  2-methylnaphthalene, naphthalene-1-(13)C-labeled
2-Methylnaphthalene is a polycyclic aromatic hydrocarbon (PAH). On February 22, 2014, NASA announced a greatly upgraded database for detecting and monitoring PAHs, including 2-methylnaphthalene, in the universe. According to NASA scientists, over 20% of the carbon in the universe may be associated with PAHs, possible starting materials for the formation of life.
CHRYSENE (65996-93-2, 50-32-8, 218-01-9)  
Chrysene is a polycyclic aromatic hydrocarbon (PAH) with the molecular formula C 18H 12 that consists of four fused benzene rings. It is a natural constituent of coal tar, from which it was first isolated and characterized. It is also found in creosote at levels of 0.5-6 mg/kg.
Dioxin (1746-01-6)  
TCDD  ·  PCDD  ·  Tetrachlorodibenzodioxin
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a polychlorinated dibenzo-p-dioxin (sometimes shortened, though inaccurately, to simply "dioxin") with the chemical formula C 12H 4Cl 4O 2. TCDD is a colorless solid with no distinguishable odor at room temperature. It is usually formed as a side product in organic synthesis and burning of organic materials.
1-METHYLNAPHTHALENE (90-12-0, 1321-94-4)  
1-Methylnaphthalene is a polycyclic aromatic hydrocarbon (PAH). It has a cetane number of zero, and was previously used as the lower reference for cetane number. However, due to the expense and handling difficulty of 1-methylnaphthalene, it was replaced in this capacity by isocetane, with a CN of 15.
1,1,1,2-TETRACHLOROETHANE (23425-39-0, 630-20-6)  
1,1,1,2-Tetrachloroethane is a chlorinated hydrocarbon. It is a colorless liquid with a sweet chloroform-like odor. It is used as a solvent and in the production of wood stains and varnishes.
2-CHLORONAPHTHALENE (1321-65-9, 1335-88-2, 91-58-7)  
2-Chloronaphthalene is an organochlorine chemical compound, a chlorinated derivative of naphthalene. Its chemical formula is C 10H 7Cl. The compound is an isomer for 1-chloronaphthalene.
ACENAPHTHENE (83-32-9)  
Acenaphthene is a polycyclic aromatic hydrocarbon (PAH) consisting of naphthalene with an ethylene bridge connecting positions 1 and 8. It is a colourless solid. Coal tar consists of about 0.3% of this compound.
1,2,3,4-Tetrahydronaphthalene (68412-24-8, 119-64-2)  
tetralin
Tetralin (1,2,3,4-tetrahydronaphthalene) is a hydrocarbon having the chemical formula C10H12. This molecule is similar to the naphthalene chemical structure except that one ring is saturated.
mescaline (54-04-6)  
Peyote  ·  Trimethoxyphenethylamine  ·  Mezcalin
Mescaline (3,4,5-trimethoxyphenethylamine) is a naturally occurring psychedelic alkaloid of the phenethylamine class, known for its hallucinogenic effects comparable to those of LSD and psilocybin. It occurs naturally in the peyote cactus (Lophophora williamsii), the San Pedro cactus (Echinopsis pachanoi), the Peruvian torch (Echinopsis peruviana), and other members of the Cactaceae plant family. It is also found in small amounts in certain members of the Fabaceae (bean) family, including Acacia berlandieri.
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