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Pyrazoles, Monoamine oxidase inhibitors


Analgesic (1)
Analgesics (1)
Anti-inflammatory agents (1)
Anti-inflammatory and antirheumatic products (1)
Antipyretics (1)
Cyclic compounds (1)
Dopamine reuptake inhibitors (1)
Drugs acting on the musculoskeletal system (1)
Drugs acting on the nervous system (1)
Five-membered rings (1)
Monoamine reuptake inhibitors (1)
Nonsteroidal anti-inflammatory drugs (1)
Psychoactive drugs (1)

Difenamizole (20170-20-1, 20170-21-2)  
Difenamizole (INN) (brand name Pasalin; former developmental code name AP-14) is a nonsteroidal anti-inflammatory drug (NSAID) and analgesic of the pyrazolone group related to metamizole. It has monoaminergic properties, including inhibition of monoamine oxidase, augmentation of pargyline-induced elevation of striatal dopamine levels, inhibition of K+-induced striatal dopamine release, and inhibition of the reuptake of dopamine.

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