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Pyrazoles, Pharmaceuticals

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Cyclic compounds (6)
Five-membered rings (6)
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Drugs acting on the nervous system (2)
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celecoxib (169590-42-5)  
Celebrex  ·  SC58635  ·  SC-58635
Celecoxib, sold under the brand name Celebrex among others, is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID). It is used to treat the pain and inflammation of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain in adults, painful menstruation, and juvenile rheumatoid arthritis in people two years or older. Side effects include a 37% increase in incidence of major vascular events, which include nonfatal myocardial infarction, nonfatal stroke, or death from a blood vessel-related cause.
Regadenoson (313348-27-5)  
Regadenoson (CVT-3146, Lexiscan) is an A2A adenosine receptor agonist that is a coronary vasodilator that is commonly used in pharmacologic stress testing. It produces hyperemia quickly and maintains it for a duration that is useful for radionuclide myocardial perfusion imaging. The selective nature of the drug makes it preferable to other stress agents such as adenosine, which are less selective and therefore cause more side-effects.
Rimonabant (168273-06-1, 158681-13-1)  
Rimonabant (also known as SR141716; trade names Acomplia, Zimulti) was an anorectic antiobesity drug that was first approved in Europe in 2006 but was withdrawn worldwide in 2008 due to serious psychiatric side effects; it was never approved in the United States. Rimonabant is an inverse agonist for the cannabinoid receptor CB1 and was the first drug approved in that class.
sulfaphenazole (526-08-9)  
Sulphaphenazole  ·  Phenylsulfapyrazole  ·  Sulfaphenylpyrazol
Sulfaphenazole (or sulfafenazol) is a sulfonamide antibacterial.
Lesopitron (132449-46-8)  
Lesopitron (E-4424) is a selective full agonist of the 5-HT1A receptor which is structurally related to the azapirones. In 2001 it was under development by Esteve as an anxiolytic for the treatment of generalized anxiety disorder (GAD). It made it to phase II clinical trials but was apparently discontinued as no new information on lesopitron has surfaced since.
Meclinertant (146362-70-1)  
Meclinertant (SR-48692) is a drug which acts as a selective, non-peptide antagonist at the neurotensin receptor NTS1, and was the first non-peptide antagonist developed for this receptor. It is used in scientific research to explore the interaction between neurotensin and other neurotransmitters in the brain, and produces anxiolytic, anti-addictive and memory-impairing effects in animal studies.

Related Results:
ISOXAZOLE (288-14-2)  
Isoxazoles
Isoxazole is an azole with an oxygen atom next to the nitrogen. It is also the class of compounds containing this ring. Isoxazolyl is the univalent radical derived from isoxazole.
Indoline (496-15-1)  
2,3-dihydro-1H-indole
Indoline is an aromatic heterocyclic organic compound with the chemical formula C8H9N. It has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing ring. The compound is based on the indole structure, but the 2-3 bond is saturated.
883-44-3 (883-44-3)  
2-(3-hydroxypropyl)isoindoline-1,3-dione
PHTHALIMIDE (85-41-6)  
potassium phthalimide  ·  phthalimide potassium salt  ·  phthalimide calcium (2:1) salt
Phthalimide is the organic compound with the formula C6H4(CO)2NH. It is the imide derivative of phthalic anhydride. It is a sublimable white solid that is slightly soluble in water but more so upon addition of base.
QUINOXALINE (91-19-0, 31799-17-4)  
A quinoxaline, also called a benzopyrazine, in organic chemistry, is a heterocyclic compound containing a ring complex made up of a benzene ring and a pyrazine ring. It is isomeric with other naphthyridines including quinazoline, phthalazine and cinnoline. It is a colorless oil that melts just above room temperature.
1533-45-5 (1533-45-5)  
2,2'-(vinylenedi-4-phenylene)bis(benzoxazole)  ·  2,2'-(vinylenedi-p-phenylene)bis(benzoxazole)
2-Chlorobenzenesulfonamide (6961-82-6)  
o-chlorobenzenesulfonamide
Related searches
Pyrazoles
Pharmaceuticals
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