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Pyrazoles, Pyrazolecarboxamides, Iodoarenes

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AM251 (183232-66-8)  
AM 251  ·  N-(piperidin-1-yl)-1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxamide  ·  N-(piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide
AM-251 is an inverse agonist at the CB1 cannabinoid receptor. AM-251 is structurally very close to SR141716A (rimonabant); both are biarylpyrazole cannabinoid receptor antagonists. In AM-251 the p-chloro group attached to the phenyl substituent at C-5 of the pyrazole ring is replaced with a p-iodo group.

Related Results:
ISOXAZOLE (288-14-2)  
Isoxazoles
Isoxazole is an azole with an oxygen atom next to the nitrogen. It is also the class of compounds containing this ring. Isoxazolyl is the univalent radical derived from isoxazole.
OXAZOLE (288-42-6)  
Oxazole is the parent compound for a vast class of heterocyclic aromatic organic compounds. These are azoles with an oxygen and a nitrogen separated by one carbon. Oxazoles are aromatic compounds but less so than the thiazoles.
Indoline (496-15-1)  
2,3-dihydro-1H-indole
Indoline is an aromatic heterocyclic organic compound with the chemical formula C8H9N. It has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing ring. The compound is based on the indole structure, but the 2-3 bond is saturated.
1533-45-5 (1533-45-5)  
2,2'-(vinylenedi-4-phenylene)bis(benzoxazole)  ·  2,2'-(vinylenedi-p-phenylene)bis(benzoxazole)
INDOLIZINE (274-40-8)  
Indolizine (Chemical formula C8H7N) is a heterocyclic aromatic organic compound that is an isomer of indole. The saturated analog indolizidine forms the structural core of a variety of alkaloids such as swainsonine.
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Pyrazoles
Pyrazolecarboxamides
Iodoarenes
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