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Pyrazoles, matrixscientific.com, Drugs acting on the gastrointestinal system and metabolism, Opioids, Five-membered rings, Opioid antagonists

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Rimonabant (168273-06-1, 158681-13-1)  
Rimonabant (also known as SR141716; trade names Acomplia, Zimulti) was an anorectic antiobesity drug that was first approved in Europe in 2006 but was withdrawn worldwide in 2008 due to serious psychiatric side effects; it was never approved in the United States. Rimonabant is an inverse agonist for the cannabinoid receptor CB1 and was the first drug approved in that class.

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TENOCYCLIDINE (21500-98-1, 1867-65-8)  
Tenocyclidine (TCP) was discovered by a team at Parke Davis in the late 1950s. It is a dissociative anesthetic drug with psychostimulant and hallucinogenic effects. It is similar in effects to phencyclidine (PCP) but is considerably more potent.
15532-75-9 (15532-75-9)  
TFMPP  ·  1-(m-trifluoromethylphenyl)piperazine  ·  1-(3-trifluoromethylphenyl)piperazine
3-Trifluoromethylphenylpiperazine (TFMPP) is a recreational drug of the piperazine chemical class. Usually in combination with its analogue benzylpiperazine (BZP), it is sold as an alternative to the illicit drug MDMA ("Ecstasy") under the name "Legal X".
1-PHENYLPIPERAZINE (92-54-6)  
phenylpiperazine  ·  phenylpiperazine monohydrochloride  ·  phenylpiperazine dihydrobromide
1-Phenylpiperazine is a simple chemical compound featuring a phenyl group bound to a piperazine ring. The suffix ‘-piprazole’ is sometimes used in the names of drugs to indicate they belong to this class. A number of phenylpiperazine derivatives are drugs, including: Pharmaceuticals: Research chemicals: Designer drugs:
1-Phenylpiperazine hydrochloride (2210-93-7)  
phenylpiperazine  ·  1-phenylpiperazine  ·  phenylpiperazine monohydrochloride
Atevirdine (136816-75-6)  
Ateviridine is non-nucleoside reverse transcriptase inhibitor that has been studied for the treatment of HIV.
1-Phenylpiperazine dihydrochloride (4004-95-9)  
phenylpiperazine  ·  1-phenylpiperazine  ·  phenylpiperazine monohydrochloride
1-(3-Chlorophenyl)piperazine (6640-24-0)  
m-CPP  ·  1-(3-chlorophenyl)piperazine dihydrochloride  ·  m-chlorophenylpiperazine
meta-Chlorophenylpiperazine (mCPP) is a psychoactive drug of the phenylpiperazine class. It was initially developed in the late-1970s and used in scientific research before being sold as a designer drug in the mid-2000s. It has been detected in pills touted as legal alternatives to illicit stimulants in New Zealand and pills sold as "ecstasy" in Europe and the United States.
cloperastine (3703-76-2)  
1-(2-((4-chloro-alpha-phenylbenzyl)oxy)ethyl)piperidine  ·  cloperastine hydrochloride
Cloperastine (INN) or cloperastin, also known as cloperastine hydrochloride (JAN) (brand names Hustazol, Nitossil, Seki) and cloperastine fendizoate (or hybenzoate), is an antitussive and antihistamine that is marketed as a cough suppressant in Japan, Hong Kong, and in some European countries. It was first introduced in 1972 in Japan, and then in Italy in 1981. The precise mechanism of action of cloperastine is not fully clear, but several different biological activities have been identified for the drug, of which include: ligand of the σ1 receptor (Ki = 20 nM) (likely an agonist), GIRK channel blocker (described as "potent"), antihistamine (Ki = 3.8 nM for the H1 receptor), and anticholinergic.
Compound VII (98033-68-2)  
WIN 53338  ·  WIN-53338  ·  WIN53338
ACEFYLLINE PIPERAZINE (18833-13-1, 5690-66-4)  
acephylline piperazinate  ·  Minophylline  ·  Etaphylline
1-Benzylpiperidine (2905-56-8)  
N-benzylpiperidine  ·  1-benzylpiperidine hydrochloride
1-Methyl-3-phenylpiperazine (5271-27-2)  
931115-08-1  ·  (3S)-1-methyl-3-phenylpiperazine
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