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Pyrazoles, matrixscientific.com, Drugs acting on the gastrointestinal system and metabolism, Opioids, Five-membered rings, Psychoactive drugs, Six-membered rings, Pyrazolecarboxamides

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Rimonabant (168273-06-1, 158681-13-1)  
Rimonabant (also known as SR141716; trade names Acomplia, Zimulti) was an anorectic antiobesity drug that was first approved in Europe in 2006 but was withdrawn worldwide in 2008 due to serious psychiatric side effects; it was never approved in the United States. Rimonabant is an inverse agonist for the cannabinoid receptor CB1 and was the first drug approved in that class.

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TENOCYCLIDINE (21500-98-1, 1867-65-8)  
Tenocyclidine (TCP) was discovered by a team at Parke Davis in the late 1950s. It is a dissociative anesthetic drug with psychostimulant and hallucinogenic effects. It is similar in effects to phencyclidine (PCP) but is considerably more potent.
1-PHENYLPIPERAZINE (92-54-6)  
phenylpiperazine  ·  phenylpiperazine monohydrochloride  ·  phenylpiperazine dihydrobromide
1-Phenylpiperazine is a simple chemical compound featuring a phenyl group bound to a piperazine ring. The suffix ‘-piprazole’ is sometimes used in the names of drugs to indicate they belong to this class. A number of phenylpiperazine derivatives are drugs, including: Pharmaceuticals: Research chemicals: Designer drugs:
cloperastine (3703-76-2)  
1-(2-((4-chloro-alpha-phenylbenzyl)oxy)ethyl)piperidine  ·  cloperastine hydrochloride
Cloperastine (INN) or cloperastin, also known as cloperastine hydrochloride (JAN) (brand names Hustazol, Nitossil, Seki) and cloperastine fendizoate (or hybenzoate), is an antitussive and antihistamine that is marketed as a cough suppressant in Japan, Hong Kong, and in some European countries. It was first introduced in 1972 in Japan, and then in Italy in 1981. The precise mechanism of action of cloperastine is not fully clear, but several different biological activities have been identified for the drug, of which include: ligand of the σ1 receptor (Ki = 20 nM) (likely an agonist), GIRK channel blocker (described as "potent"), antihistamine (Ki = 3.8 nM for the H1 receptor), and anticholinergic.
15532-75-9 (15532-75-9)  
TFMPP  ·  1-(m-trifluoromethylphenyl)piperazine  ·  1-(3-trifluoromethylphenyl)piperazine
3-Trifluoromethylphenylpiperazine (TFMPP) is a recreational drug of the piperazine chemical class. Usually in combination with its analogue benzylpiperazine (BZP), it is sold as an alternative to the illicit drug MDMA ("Ecstasy") under the name "Legal X".
BUTYROPHENONE (495-40-9)  
Butyrophenone is a chemical compound; some of its derivatives (called commonly butyrophenones) are used to treat various psychiatric disorders such as schizophrenia, as well as acting as antiemetics. Examples of butyrophenones include: Haloperidol, the most widely used classical antipsychotic drug in this class Benperidol, the most potent commonly used antipsychotic ( 200 times more potent than chlorpromazine)
MMDA (13674-05-0)  
MMDA (3-methoxy-4,5-methylenedioxyamphetamine; 5-methoxy-MDA) is a psychedelic and entactogen drug of the amphetamine class. It is an analogue of lophophine, MDA, and MDMA. MMDA was described by Alexander Shulgin in his book PiHKAL.
ACEFYLLINE PIPERAZINE (18833-13-1, 5690-66-4)  
acephylline piperazinate  ·  Minophylline  ·  Etaphylline
1-Benzylpiperidine (2905-56-8)  
N-benzylpiperidine  ·  1-benzylpiperidine hydrochloride
2-HYDROXYPYRIDINE (72762-00-6, 37342-64-6, 142-08-5)  
2-pyridinone  ·  2-pyridone  ·  2-hydroxypyridine sodium salt
2-Pyridone is an organic compound with the formula C 5H 4NH(O). It is a colourless solid. It is well known to form hydrogen bonded dimers and it is also a classic case of a compound that exists as tautomers.
1-(4-Fluorophenyl)piperazine (2252-63-3)  
para-fluoro-phenylpiperazine  ·  p-fluoro-phenylpiperazine  ·  4-fluoro-phenylpiperazine
para-Fluorophenylpiperazine (pFPP, 4-FPP, 4-Fluorophenylpiperazine; Fluoperazine, Flipiperazine) is a piperazine derivative with mildly psychedelic and euphoriant effects. It has been sold as an ingredient in legal recreational drugs known as "Party pills", initially in New Zealand and subsequently in other countries around the world. pFPP has been found in vitro to act mainly as a 5-HT1A receptor agonist, with some additional affinity for the 5-HT2A and 5-HT2C receptors.
Phenethylamine (64-04-0)  
2-phenethylamine  ·  phenethylamine hydrobromide  ·  phenethylamine sulfate (2:1)
Phenethylamine (PEA), also known as β-phenylethylamine (β-PEA) and 2-phenylethan-1-amine, is an organic compound, natural monoamine alkaloid, and trace amine which acts as a central nervous system stimulant in humans. Phenylethylamine functions as a monoaminergic neuromodulator and, to a lesser extent, a neurotransmitter in the human central nervous system. It is biosynthesized from the amino acid L-phenylalanine by enzymatic decarboxylation via the enzyme aromatic L-amino acid decarboxylase.
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