Cyclic compounds (17)
Five-membered rings (17)
Aromatic ketones (2)
Beta blockers (1)
COX-2 inhibitors (1)
Food Additives (1)
Sigma Aldrich (4)
AK Scientific (3)
Oakwood Chemical (3)
TCI Chemicals (1)
atorvastatin (134523-00-5, 110862-48-1, 134523-03-8)
Atorvastatin, marketed under the trade name Lipitor among others, is a member of the medication class known as statins, which are used primarily as a lipid-lowering agent and for prevention of events associated with cardiovascular disease. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body. Atorvastatin was first made in August 1985 at Warner-Lambert's Parke-Davis research facility in Ann Arbor, Michigan by a team led by Bruce Roth.
PYRROLE (16199-06-7, 30604-81-0, 109-97-7)
Pyrrole is a heterocyclic aromatic organic compound, a five-membered ring with the formula C4H4NH. It is a colorless volatile liquid that darkens readily upon exposure to air. Substituted derivatives are also called pyrroles, e.g., N-methylpyrrole, C4H4NCH3.
Chlorfenapyr is a pesticide, and specifically a pro-insecticide (meaning it is metabolized into an active insecticide after entering the host), derived from a class of microbially produced compounds known as halogenated pyrroles. The United States Environmental Protection Agency initially denied registration in 2000 for use on cotton primarily because of concerns that the insecticide was toxic to birds and because effective alternatives were available. However, it was registered by EPA in January, 2001 for use on non-food crops in greenhouses.
Tolectin · Tolmetin Sodium · McN-2559
Tolmetin is a nonsteroidal anti-inflammatory drug (NSAID) of the heterocyclic acetic acid derivative class. It is used primarily to reduce hormones that cause pain, swelling, tenderness, and stiffness in conditions such as osteoarthritis and rheumatoid arthritis, including juvenile rheumatoid arthritis. In the United States it is marketed as Tolectin and comes as a tablet or capsule.
Zomax · zomepirac sodium · zomepirac potassium
Zomepirac is an orally effective nonsteroidal anti-inflammatory drug (NSAID) that has antipyretic actions. It was developed by McNeil Pharmaceutical, approved by the FDA in 1980, and sold as the sodium salt zomepirac sodium, under the brand name Zomax. Due to its clinical effectiveness, it was preferred by doctors in many situations and obtained a large share of the analgesics market; however, it was subsequently withdrawn in March 1983 due to its tendency to cause serious anaphylaxis in an unpredictable subset of the patient population.
Ryanodine is a poisonous diterpenoid found in the South American plant Ryania speciosa (Salicaceae). It was originally used as an insecticide. The compound has extremely high affinity to the open-form ryanodine receptor, a group of calcium channels found in skeletal muscle, smooth muscle, and heart muscle cells.
Amtolmetin guacil (87344-06-7)
Amtolmetin guacil is a NSAID which is a prodrug of tolmetin sodium.
SB 206553 (158942-04-2)
SB-206553 is a drug which acts as a mixed antagonist for the 5-HT2B and 5-HT2C serotonin receptors. It has anxiolytic properties in animal studies and interacts with a range of other drugs. It has also been shown to act as a positive allosteric modulator of α7 nicotinic acetylcholine receptors.
Isamoltan (116861-00-8, 55050-95-8, 99740-06-4)
Isamoltane (CGP-361A) is a drug used in scientific research. It acts as an antagonist at the β-adrenergic, 5-HT1A, and 5-HT1B receptors. It has about five times the potency for the 5-HT1B receptor (21 nmol/l) over the 5-HT1A receptor (112 nmol/l).
diviminol · viminol, alphaS-(alphaR*(R*,R*))-isomer · 1-(1-(2-chlorobenzyl)-2-pyrrolyl)-2-(di-sec-butylamino)ethanol
Pamicogrel is a cyclooxygenase inhibitor that was under development for its anti-platelet-aggregation effects.
Aloracetam (INN) is a drug described as a nootropic which is closely related to, but technically not of (as it lacks a pyrrolidone ring), the racetam family of compounds. It was studied by Aventis for the treatment of Alzheimer's disease, but was never marketed.