Similar to 6,7-Dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline , Respiratory agents, PDE4 inhibitors
drotaverine (14009-24-6, 985-12-6)
Drotaverine (INN, also known as drotaverin) is an antispasmodic drug, used to enhance cervical dilation during childbirth. It is structurally related to papaverine, is a selective inhibitor of phosphodiesterase 4, and has no anticholinergic effects. It is available in Asian and Eastern European countries under several brand names.
Protein kinase inhibitor H-8 (84478-11-5)
H8 protein kinase inhibitor · N-(2-(methylamino)ethyl)-5-isoquinolinesulfonamide · H-8 protein kinase inhibitor
1,3,5-tris(3-isocyanato-4-methylphenyl)-1,3,5-triazinane-2,4,6-trione (26603-40-7, 8060-82-0)
brobenzoxaldine, broxyquinoline drug combination · Intestopan · Enteroquin
Imatinib, sold under the brand names Gleevec among others, is a medication used to treat cancer. Specifically, it is used for chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL) that is Philadelphia chromosome-positive (Ph+) and certain types of gastrointestinal stromal tumors (GIST), systemic mastocytosis, and myelodysplastic syndrome. It is taken by mouth.
N-(2-aminoethyl)-5-isoquinolinesulfonamide · H-9 · protein kinase C inhibitor H-9
MS 275 · MS-27-275 · N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide
Entinostat, also known as SNDX-275 and MS-275, is a benzamide histone deacetylase inhibitor undergoing clinical trials for treatment of various cancers. Entinostat inhibits class I HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM, respectively. Syndax pharmaceuticals currently holds the rights to Entinostat and recently received $26.6 million in funds to advance treatments of resistant cancers using epigenetic tools.
2-ACBDS · 2-amino-4-chloro-m-benzenedisulfonamide · 4-amino-6-chloro-1,3-benzenedisulfonamide
Thalomid · Celgene Brand of Thalidomide · Sedoval
Thalidomide, sold under the brand name Immunoprin, among others, is an immunomodulatory drug and the prototype of the thalidomide class of drugs. Today, thalidomide is used mainly as a treatment of certain cancers (multiple myeloma) and of a complication of leprosy. Thalidomide was first marketed in 1957 in West Germany under the trade-name Contergan.
4(3H)-quinazolinone · quinazolin-4-one
SP600125 · anthra(1,9-cd)pyrazol-6(2H)-one · NSC75890
1,9-Pyrazoloanthrone is a chemical compound that is a derivative of anthrone. It is used in biochemical studies as an inhbitor of c-Jun N-terminal kinases (JNKs). Derivatives of 1,9-pyrazoloanthrone have a variety of biological activities.
4-quinazolinamine · 15018-66-3